2023
Characteristics of trichotillomania and excoriation disorder across the lifespan
Lin A, Farhat L, Flores J, Levine J, Fernandez T, Bloch M, Olfson E. Characteristics of trichotillomania and excoriation disorder across the lifespan. Psychiatry Research 2023, 322: 115120. PMID: 36842397, PMCID: PMC10023474, DOI: 10.1016/j.psychres.2023.115120.Peer-Reviewed Original ResearchConceptsExcoriation disorderClinical characteristicsSkin-picking severityAttention-deficit/hyperactivity disorderCo-occurring conditionsBody-focused repetitive behaviorsObsessive-compulsive disorderSeverity scoreCurrent symptomsSignificant positive correlationTrichotillomaniaHyperactivity disorderDisordersSelf-reported anxietyAge 4High rateSubtypesSelf-report measuresSeverityCross-sectional survey responsesRepetitive behaviorsAdulthoodPositive correlation
2016
CYP2A6 metabolism in the development of smoking behaviors in young adults
Olfson E, Bloom J, Bertelsen S, Budde JP, Breslau N, Brooks A, Culverhouse R, Chan G, Chen L, Chorlian D, Dick DM, Edenberg HJ, Hartz S, Hatsukami D, Hesselbrock VM, Johnson EO, Kramer JR, Kuperman S, Meyers JL, Nurnberger J, Porjesz B, Saccone NL, Schuckit MA, Stitzel J, Tischfield JA, Rice JP, Goate A, Bierut LJ. CYP2A6 metabolism in the development of smoking behaviors in young adults. Addiction Biology 2016, 23: 437-447. PMID: 28032407, PMCID: PMC5491369, DOI: 10.1111/adb.12477.Peer-Reviewed Original ResearchConceptsNicotine dependenceSlow metabolizersDaily smokersYoung adultsSmoking behaviorCYP2A6 variationNicotine metabolismRole of CYP2A6Adult daily smokersDevelopment of dependenceCollaborative Genetics StudyGenetics of AlcoholismSmoking milestonesCytochrome P450 2A6Young adult daily smokersNormal metabolizersCollaborative studyDaily smokingFirst cigaretteSecondary analysisCYP2A6 variantsMetabolizersYoung adulthoodP450 2A6Conflicting resultsThe significant impact of education, poverty, and race on Internet-based research participant engagement
Hartz SM, Quan T, Ibiebele A, Fisher SL, Olfson E, Salyer P, Bierut LJ. The significant impact of education, poverty, and race on Internet-based research participant engagement. Genetics In Medicine 2016, 19: 240-243. PMID: 27467456, PMCID: PMC5274598, DOI: 10.1038/gim.2016.91.Peer-Reviewed Original ResearchImplications of Personal Genomic Testing for Health Behaviors: The Case of Smoking
Olfson E, Hartz S, Carere DA, Green RC, Roberts JS, Bierut LJ, Group F. Implications of Personal Genomic Testing for Health Behaviors: The Case of Smoking. Nicotine & Tobacco Research 2016, 18: 2273-2277. PMID: 27613923, PMCID: PMC5103936, DOI: 10.1093/ntr/ntw168.Peer-Reviewed Original ResearchConceptsCurrent smokersSmoking-related diseasesPersonal genomic testingGenetic risk resultsFormer smokersGenomic testingLung cancerConsumer genomic testingGenetic riskSmoking behaviorHealth behaviorsFalse reassuranceUnhealthy behaviorsBaseline current smokersSame smoking statusConsumer personal genomic testingSmoking-related illnessesHigher quit ratesGenomic test resultsCase of smokingBehavior 6 monthsSmoking statusHeart diseaseQuit ratesGenomic testing results
2015
When Does Choice of Accuracy Measure Alter Imputation Accuracy Assessments?
Ramnarine S, Zhang J, Chen LS, Culverhouse R, Duan W, Hancock DB, Hartz SM, Johnson EO, Olfson E, Schwantes-An TH, Saccone NL. When Does Choice of Accuracy Measure Alter Imputation Accuracy Assessments? PLOS ONE 2015, 10: e0137601. PMID: 26458263, PMCID: PMC4601794, DOI: 10.1371/journal.pone.0137601.Peer-Reviewed Original ResearchRare, low frequency and common coding variants in CHRNA5 and their contribution to nicotine dependence in European and African Americans
Olfson E, Saccone NL, Johnson EO, Chen LS, Culverhouse R, Doheny K, Foltz SM, Fox L, Gogarten SM, Hartz S, Hetrick K, Laurie CC, Marosy B, Amin N, Arnett D, Barr RG, Bartz TM, Bertelsen S, Borecki IB, Brown MR, Chasman DI, van Duijn CM, Feitosa MF, Fox ER, Franceschini N, Franco OH, Grove ML, Guo X, Hofman A, Kardia SL, Morrison AC, Musani SK, Psaty BM, Rao DC, Reiner AP, Rice K, Ridker PM, Rose LM, Schick UM, Schwander K, Uitterlinden AG, Vojinovic D, Wang JC, Ware EB, Wilson G, Yao J, Zhao W, Breslau N, Hatsukami D, Stitzel JA, Rice J, Goate A, Bierut LJ. Rare, low frequency and common coding variants in CHRNA5 and their contribution to nicotine dependence in European and African Americans. Molecular Psychiatry 2015, 21: 601-607. PMID: 26239294, PMCID: PMC4740321, DOI: 10.1038/mp.2015.105.Peer-Reviewed Original Research
2012
Convergence of Genome‐Wide Association and Candidate Gene Studies for Alcoholism
Olfson E, Bierut LJ. Convergence of Genome‐Wide Association and Candidate Gene Studies for Alcoholism. Alcohol Clinical And Experimental Research 2012, 36: 2086-2094. PMID: 22978509, PMCID: PMC3521088, DOI: 10.1111/j.1530-0277.2012.01843.x.Peer-Reviewed Original Research