1984
Role of aldosterone in the mechanism of potassium adaptation in the initial collecting tubule
Hirsch D, Kashgarian M, Boulpaep E, Hayslett J. Role of aldosterone in the mechanism of potassium adaptation in the initial collecting tubule. Kidney International 1984, 26: 798-807. PMID: 6099857, DOI: 10.1038/ki.1984.221.Peer-Reviewed Original ResearchConceptsInitial collecting tubuleCollecting tubuleDistal convolutionAldosterone levelsPotassium adaptationChronic potassium loadingMineralocorticoid-sensitive tissuesRole of aldosteronePlasma aldosterone levelsAction of aldosteroneIntact adrenal glandsPotassium loadingPhysiological plasma levelsChronic hyperaldosteronismTransepithelial potential differenceChronic administrationEpithelial changesAdrenal glandPlasma levelsDietary potassium loadingBasal valuesAldosteroneTubule cellsNephron segmentsTarget tissues
1978
Factors influencing transepithelial potential difference in mammalian distal tubule
Hayslett J, Boulpaep E, Giebisch G. Factors influencing transepithelial potential difference in mammalian distal tubule. American Journal Of Physiology 1978, 234: f182-f191. PMID: 629352, DOI: 10.1152/ajprenal.1978.234.3.f182.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsBiological Transport, ActiveChloridesElectrolytesElectrophysiologyEpitheliumKidney TubulesKidney Tubules, DistalMaleMembrane PotentialsPotassiumRatsSodium
1977
Electrical characteristics of the mammalian distal tubule: Comparison of Ling-Gerard and macroelectrodes
Hayslett J, Boulpaep E, Kashgarian M, Giebisch G. Electrical characteristics of the mammalian distal tubule: Comparison of Ling-Gerard and macroelectrodes. Kidney International 1977, 12: 324-331. PMID: 604621, DOI: 10.1038/ki.1977.119.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsElectricityElectrodesFemaleKidney TubulesKidney Tubules, DistalMaleMicroelectrodesNephronsRats
1976
Electrical phenomena in the nephron
Boulpaep E. Electrical phenomena in the nephron. Kidney International 1976, 9: 88-102. PMID: 940266, DOI: 10.1038/ki.1976.14.Peer-Reviewed Original ResearchConceptsSingle barrierAvailable experimental dataIon movementElectrical conductanceElectrical phenomenaSingle cell membraneSingle membrane levelElectric currentElectrical propertiesPotential differenceExperimental dataDiffusion barrierDistinctive physical propertiesElectrical characteristicsPhysical propertiesIndividual cell membranesDiffusion boundariesElectrical behaviorPotential gradientMembrane approachConjugate forcesBiological membranesElectrochemical potential gradientTransport processesMicroscopic level