1998
Transcellular Chloride Pathways in Ambystoma Proximal Tubule
Abdulnour-Nakhoul S, Boulpaep E. Transcellular Chloride Pathways in Ambystoma Proximal Tubule. The Journal Of Membrane Biology 1998, 166: 15-35. PMID: 9784583, DOI: 10.1007/s002329900444.Peer-Reviewed Original ResearchConceptsProximal tubulesChloride channel blockerContribution of transportersAmbystoma proximal tubuleTransepithelial potential differenceDisulfonic stilbeneCl-HCO3 exchangeFree RingerLines of evidenceTubulesBasolateral cell membraneLumenNa-independent ClMembrane potentialBasolateral membraneApical membrane potentialAiClBlockers
1984
Role of aldosterone in the mechanism of potassium adaptation in the initial collecting tubule
Hirsch D, Kashgarian M, Boulpaep E, Hayslett J. Role of aldosterone in the mechanism of potassium adaptation in the initial collecting tubule. Kidney International 1984, 26: 798-807. PMID: 6099857, DOI: 10.1038/ki.1984.221.Peer-Reviewed Original ResearchConceptsInitial collecting tubuleCollecting tubuleDistal convolutionAldosterone levelsPotassium adaptationChronic potassium loadingMineralocorticoid-sensitive tissuesRole of aldosteronePlasma aldosterone levelsAction of aldosteroneIntact adrenal glandsPotassium loadingPhysiological plasma levelsChronic hyperaldosteronismTransepithelial potential differenceChronic administrationEpithelial changesAdrenal glandPlasma levelsDietary potassium loadingBasal valuesAldosteroneTubule cellsNephron segmentsTarget tissues
1983
Rheogenic transport in the renal proximal tubule.
Sackin H, Boulpaep E. Rheogenic transport in the renal proximal tubule. The Journal Of General Physiology 1983, 82: 819-851. PMID: 6319539, PMCID: PMC2228722, DOI: 10.1085/jgp.82.6.819.Peer-Reviewed Original Research
1980
Organic substrate effects on and heterogeneity of Necturus proximal tubule function
Forster J, Steels P, Boulpaep E. Organic substrate effects on and heterogeneity of Necturus proximal tubule function. Kidney International 1980, 17: 479-490. PMID: 6771454, DOI: 10.1038/ki.1980.56.Peer-Reviewed Original ResearchConceptsProximal tubulesFluid absorptionProximal tubule functionPeritubular membrane potential differenceNet fluid absorptionTransepithelial potential differenceEntry of sodium
1979
Effect of amiloride on the apical cell membrane cation channels of a sodium-absorbing, potassium-secreting renal epithelium
O'Neil R, Boulpaep E. Effect of amiloride on the apical cell membrane cation channels of a sodium-absorbing, potassium-secreting renal epithelium. The Journal Of Membrane Biology 1979, 50: 365-387. PMID: 513119, DOI: 10.1007/bf01868898.Peer-Reviewed Original ResearchConceptsLumen-negative transepithelial potential differenceActive Na absorptionApical cell membraneEffects of amilorideEquivalent short-circuit currentTransepithelial potential differenceNa absorptionMaximum inhibitory concentrationAmilorideDiuretic amilorideCation channelsCell membraneNa channelsInhibitory concentrationRenal epitheliumMembrane cation channelsRemoval of NaAbsence of NaTight junctionsPerfusateK permeabilityTubulesLumen
1978
Factors influencing transepithelial potential difference in mammalian distal tubule
Hayslett J, Boulpaep E, Giebisch G. Factors influencing transepithelial potential difference in mammalian distal tubule. American Journal Of Physiology 1978, 234: f182-f191. PMID: 629352, DOI: 10.1152/ajprenal.1978.234.3.f182.Peer-Reviewed Original Research
1977
Electrical characteristics of the mammalian distal tubule: Comparison of Ling-Gerard and macroelectrodes
Hayslett J, Boulpaep E, Kashgarian M, Giebisch G. Electrical characteristics of the mammalian distal tubule: Comparison of Ling-Gerard and macroelectrodes. Kidney International 1977, 12: 324-331. PMID: 604621, DOI: 10.1038/ki.1977.119.Peer-Reviewed Original Research