2023
Reply Long-Term Patient Outcomes After Femoropopliteal Peripheral Vascular Intervention in Patients With Intermittent Claudication
Altin S, Curtis J. Reply Long-Term Patient Outcomes After Femoropopliteal Peripheral Vascular Intervention in Patients With Intermittent Claudication. JACC Cardiovascular Interventions 2023, 16: 2336. PMID: 37758390, DOI: 10.1016/j.jcin.2023.08.027.Peer-Reviewed Original ResearchMeSH KeywordsFemoral ArteryHumansIntermittent ClaudicationPeripheral Arterial DiseasePopliteal ArteryRetrospective StudiesTreatment OutcomeVascular PatencyUse of telemedicine facilitated by trained telepresenters to manage advanced peripheral artery disease in rural areas
Breen T, Peake J, Keefe H, Moran J, Kunjukutty F, Pfau S, Altin S. Use of telemedicine facilitated by trained telepresenters to manage advanced peripheral artery disease in rural areas. Vascular Medicine 2023, 28: 239-240. PMID: 36628596, DOI: 10.1177/1358863x221148797.Peer-Reviewed Original Research
2022
Sex-Based Differences in Periprocedural Complications Following Lower Extremity Peripheral Vascular Intervention
Altin S, Gitto M, Secemsky E, Rao S, Hess C. Sex-Based Differences in Periprocedural Complications Following Lower Extremity Peripheral Vascular Intervention. Circulation Cardiovascular Interventions 2022, 15: e011768. PMID: 35938403, DOI: 10.1161/circinterventions.121.011768.Peer-Reviewed Original ResearchMeSH KeywordsFemaleHematomaHumansLower ExtremityMaleOdds RatioPeripheral Arterial DiseaseRetrospective StudiesRisk FactorsTreatment OutcomeConceptsLower extremity peripheral vascular interventionsPeripheral vascular interventionsSymptomatic peripheral artery diseasePeripheral artery diseasePeriprocedural complicationsArtery diseaseHigh riskHospital mortalityKnee amputationFemale sexVascular interventionsVascular Quality Initiative registryAccess site bleedingAccess site complicationsPercutaneous coronary interventionCoronary artery diseaseSex-based outcomesMultivariate logistic regressionWarrants further investigationSex-based differencesBaseline patientSite bleedingCoronary interventionSite complicationsContemporary cohortStatins and statin intensity in peripheral artery disease.
Sagris M, Katsaros I, Giannopoulos S, Rosenberg RD, Altin SE, Rallidis L, Mena-Hurtado C, Armstrong EJ, Kokkinidis DG. Statins and statin intensity in peripheral artery disease. Vasa 2022, 51: 198-211. PMID: 35673949, DOI: 10.1024/0301-1526/a001012.Peer-Reviewed Original ResearchMeSH KeywordsAmputation, SurgicalHumansHydroxymethylglutaryl-CoA Reductase InhibitorsLower ExtremityPeripheral Arterial DiseaseRisk FactorsTreatment OutcomeConceptsMajor adverse cardiovascular eventsPeripheral artery diseaseLow-intensity statinsLoss of patencyStatin useStatin doseIntensity statinsArtery diseaseFirst-line lipid-lowering therapyAdverse cardiovascular eventsAmputation-free survivalHigher statin doseLipid-lowering therapyMyocardial infarction rateRisk of amputationImpact of statinsStatin intensityCardiovascular eventsPAD patientsCardiovascular deathCardiovascular mortalityCause mortalityInfarction rateIschemia patientsStatin treatmentSex Differences in Peripheral Artery Disease
Pabon M, Cheng S, Altin S, Sethi S, Nelson M, Moreau K, Hamburg N, Hess C. Sex Differences in Peripheral Artery Disease. Circulation Research 2022, 130: 496-511. PMID: 35175843, PMCID: PMC8919803, DOI: 10.1161/circresaha.121.320702.Peer-Reviewed Original ResearchMeSH KeywordsAnkle Brachial IndexDiabetes MellitusExercise TherapyFemaleFibrinolytic AgentsHumansHypertensionMalePeripheral Arterial DiseaseSex CharacteristicsSex FactorsSmokingConceptsPeripheral artery diseaseArtery diseaseManagement of PADSuch sex-based differencesNontraditional risk factorsSex differencesLack of diagnosisSex-based differencesImportant sex differencesIschemic cardiovascularPAD prevalenceVascular stressorSubstantial morbidityClinical presentationClinical manifestationsRisk factorsPrevalent conditionLimb eventsOverall populationVascular substratesDiseaseSex variationWomenCurrent knowledgeManifestations
2020
Predictors of Underutilization of Medical Therapy in Patients Undergoing Endovascular Revascularization for Peripheral Artery Disease
Altin S, Castro-Dominguez Y, Kennedy K, Orion K, Lanksy A, Abbott J, Aronow H. Predictors of Underutilization of Medical Therapy in Patients Undergoing Endovascular Revascularization for Peripheral Artery Disease. JACC Cardiovascular Interventions 2020, 13: 2911-2918. PMID: 33357529, DOI: 10.1016/j.jcin.2020.08.036.Peer-Reviewed Original ResearchMeSH KeywordsAngiotensin-Converting Enzyme InhibitorsCoronary Artery DiseaseFemaleHumansPeripheral Arterial DiseasePlatelet Aggregation InhibitorsRetrospective StudiesRisk FactorsTreatment OutcomeConceptsGuideline-directed medical therapyGDMT prescriptionPeripheral artery diseaseAntiplatelet agentsArtery diseaseLower extremity peripheral vascular interventionsAngiotensin receptor blocker useSymptomatic peripheral artery diseaseTraditional atherosclerotic risk factorsChronic limb-threatening ischemiaEnd-stage renal diseaseAtherosclerotic disease burdenDischarge prescription ratesGuideline-recommended therapiesAngiotensin receptor blockersAtherosclerotic risk factorsReceptor blocker useVascular Study GroupLimb-threatening ischemiaPeripheral vascular interventionsVascular Quality InitiativeCongestive heart failureCoronary artery diseaseMultivariate logistic regressionBlocker useSeasonal variation in U.S. hospitalizations for chronic limb‐threatening ischemia
Altin SE, Kim YG, Aronow HD, Armstrong EJ, Goldsweig AM, Dardik A, Lanksy AJ, Mena‐Hurtado C, Abbott JD. Seasonal variation in U.S. hospitalizations for chronic limb‐threatening ischemia. Catheterization And Cardiovascular Interventions 2020, 96: 1473-1480. PMID: 32902126, DOI: 10.1002/ccd.29261.Peer-Reviewed Original ResearchConceptsCritical limb-threatening ischemiaLimb-threatening ischemiaNational Inpatient SampleMinor amputationChronic limb-threatening ischemiaUtilization Project National Inpatient SampleProvider education effortsCoronary artery diseaseAmputation rateHospital mortalityImportant comorbidityDiabetic statusOverall cohortSecondary outcomesArtery diseaseHospital admissionPrimary outcomeHospitalization incidenceU.S. hospitalizationsDiagnosis codesInpatient SampleHigher oddsAdmission seasonHealthcare costsMortality rateUtility of Intravascular Ultrasound in Peripheral Vascular Interventions: Systematic Review and Meta-Analysis
Sheikh AB, Anantha-Narayanan M, Smolderen KG, Jelani QU, Nagpal S, Schneider M, Llanos F, Ionescu C, Regan C, Attaran R, Altin SE, Mena-Hurtado C. Utility of Intravascular Ultrasound in Peripheral Vascular Interventions: Systematic Review and Meta-Analysis. Vascular And Endovascular Surgery 2020, 54: 413-422. PMID: 32338163, DOI: 10.1177/1538574420920998.Peer-Reviewed Original ResearchConceptsPeripheral vascular interventionsPeriprocedural adverse eventsVascular complicationsAdverse eventsIntravascular ultrasoundPrimary patencyCause mortalityTechnical successMyocardial infarctionObservational studyVascular interventionsEnd pointSimilar patency ratesSimilar primary patencyPrimary end pointRate of reinterventionSecondary end pointsPeripheral arterial diseaseImproved clinical outcomesIVUS groupAmputation rateArterial diseaseClinical outcomesPatency ratesLower risk
2018
Making sense of endovascular therapies for femoropopliteal disease
Altin S, Abbott J. Making sense of endovascular therapies for femoropopliteal disease. Catheterization And Cardiovascular Interventions 2018, 91: 1329-1330. PMID: 29894589, DOI: 10.1002/ccd.27651.Peer-Reviewed Original ResearchMeSH KeywordsAngioplasty, BalloonFemoral ArteryHumansNetwork Meta-AnalysisPeripheral Arterial DiseasePopliteal ArteryTreatment OutcomeVascular PatencyConceptsTarget lesion revascularizationSubgroup of patientsRisk of restenosisLesion revascularizationEndovascular strategiesFemoropopliteal diseaseEndovascular therapyRevascularization approachEndovascular interventionLower riskSupport drugsLesion typeWarrants investigationBiomechanical forcesCommon targetRiskRevascularizationPatientsArteryRestenosisTherapyDisease