2022
Cardiometabolic disorders, inflammation and the incidence of non-alcoholic fatty liver disease: A longitudinal study comparing lean and non-lean individuals
Aneni E, Saeed G, Bittencourt M, Cainzos-Achirica M, Osondu C, Budoff M, Parise E, Santos R, Nasir K. Cardiometabolic disorders, inflammation and the incidence of non-alcoholic fatty liver disease: A longitudinal study comparing lean and non-lean individuals. PLOS ONE 2022, 17: e0266505. PMID: 35385529, PMCID: PMC8985996, DOI: 10.1371/journal.pone.0266505.Peer-Reviewed Original ResearchConceptsNon-alcoholic fatty liver diseaseRisk of NAFLDElevated blood glucoseElevated blood pressureFatty liver diseaseBlood glucoseLean individualsBlood pressureCardiometabolic disordersPhysical inactivityWaist circumferenceLiver diseaseDevelopment of NAFLDHigh-sensitivity C-reactive proteinCardiovascular disease risk stratificationSensitivity C-reactive proteinCardiometabolic risk factorsAlcohol Use Disorders Identification TestC-reactive proteinMain exposure variableDisease risk stratificationHospital Israelita Albert EinsteinDisorders Identification TestAppropriate preventive measuresAtherogenic dyslipidemia
2015
Elevated serum uric acid is associated with vascular inflammation but not coronary artery calcification in the healthy octogenarians: the Brazilian study on healthy aging
Malik R, Aneni EC, Shahrayar S, Freitas WM, Ali SS, Veledar E, Latif MA, Aziz M, Ahmed R, Khan SA, Joseph J, Feiz H, Sposito A, Nasir K. Elevated serum uric acid is associated with vascular inflammation but not coronary artery calcification in the healthy octogenarians: the Brazilian study on healthy aging. Aging Clinical And Experimental Research 2015, 28: 359-362. PMID: 26084248, DOI: 10.1007/s40520-015-0395-3.Peer-Reviewed Original ResearchConceptsSerum uric acidElevated hs-CRPCoronary artery calcificationHs-CRPSUA tertilesCardiovascular diseaseCoronary atherosclerosisHealthy octogenariansArtery calcificationVascular inflammationAssociation of SUATertiles of SUAElevated serum uric acidSensitive C-reactive proteinMedian hs-CRPClinical cardiovascular diseaseHigher SUA levelsC-reactive proteinSubclinical cardiovascular diseaseUric acidCAC burdenCAC presenceSUA levelsOverall prevalenceElderly population