2019
Prolonged Response to Pembrolizumab in Spindle Cell Squamous Cell Carcinoma Metastatic to the Central Nervous System
Liu Y, Fitzgerald B, Perry E, Pathak A, Chao HH. Prolonged Response to Pembrolizumab in Spindle Cell Squamous Cell Carcinoma Metastatic to the Central Nervous System. Journal Of Investigative Medicine High Impact Case Reports 2019, 7: 2324709619850216. PMID: 31132886, PMCID: PMC6540500, DOI: 10.1177/2324709619850216.Peer-Reviewed Case Reports and Technical NotesConceptsSquamous cell carcinomaSpindle cell squamous cell carcinomaCutaneous squamous cell carcinomaCell carcinomaCentral nervous systemNeurological deficitsAdvanced diseaseAnti-PD-1 monoclonal antibody treatmentNervous systemAnti-PD-1 therapyCentral nervous system metastasesProgressive left-sided weaknessSquamous cell carcinoma metastaticLeft-sided weaknessNervous system metastasesProgressive neurological deficitsProgression-free survivalDurable clinical responsesMonoclonal antibody treatmentRare spindle-cell variantSpindle cell variantDurability of effectDrug Administration approvalRadiation therapy optionsCarcinoma metastatic
2010
Clinical significance of neurological soft signs in schizophrenia: Factor analysis of the Neurological Evaluation Scale
Sewell RA, Perry EB, Karper LP, Bell MD, Lysaker P, Goulet JL, Brenner L, Erdos J, d'Souza DC, Seibyl JP, Krystal JH. Clinical significance of neurological soft signs in schizophrenia: Factor analysis of the Neurological Evaluation Scale. Schizophrenia Research 2010, 124: 1-12. PMID: 20855185, DOI: 10.1016/j.schres.2010.08.036.Peer-Reviewed Original ResearchConceptsNeurological Evaluation ScaleAbnormal Involuntary Movement ScaleDigit Symbol Substitution TaskWisconsin Card Sorting TestNeurologic deficitsClinical significanceExtrapyramidal Symptom Rating ScaleMore extrapyramidal symptomsBarnes Akathisia ScaleDetailed clinical assessmentNeurological soft signsSymptom Rating ScaleNegative Syndrome ScaleHigher AIMS scoresEvaluation ScaleNeurological deficitsExtrapyramidal symptomsClinical correlatesDeficit syndrome schizophreniaClinical evaluationClinical assessmentAIMS scoresLower PANSSMovement ScaleSoft signs