2005
The PhoP/PhoQ system controls the intramacrophage type three secretion system of Salmonella enterica
Bijlsma JJ, Groisman EA. The PhoP/PhoQ system controls the intramacrophage type three secretion system of Salmonella enterica. Molecular Microbiology 2005, 57: 85-96. PMID: 15948951, DOI: 10.1111/j.1365-2958.2005.04668.x.Peer-Reviewed Original ResearchConceptsSPI-2 pathogenicity islandPhoP/PhoQ systemType three secretion systemThree secretion systemPhoP proteinSecretion systemSsa genesPathogenicity islandTwo-component regulatory systemResponse regulator SsrBPhoP/PhoQRegulatory systemTwo-component systemSalmonella entericaEukaryotic cellsChromatin immunoprecipitationCentral roleDifferent regulatory systemsSalmonella virulenceUntranslated regionDistinct signalsPhoPGenesEffectorsProtein
2001
Salmonella enterica Serovar Typhimurium Response Involved in Attenuation of Pathogen Intracellular Proliferation
Cano D, Martı́nez-Moya M, Pucciarelli M, Groisman E, Casadesús J, Portillo F. Salmonella enterica Serovar Typhimurium Response Involved in Attenuation of Pathogen Intracellular Proliferation. Infection And Immunity 2001, 69: 6463-6474. PMID: 11553591, PMCID: PMC98782, DOI: 10.1128/iai.69.10.6463-6474.2001.Peer-Reviewed Original ResearchConceptsIntracellular growth rateIntracellular bacterial viabilityIntracellular proliferation rateNormal rat kidney fibroblastsBacterial overgrowthNonphagocytic host cellsRat kidney fibroblastsNormal fibroblast cellsIntracellular bacterial proliferationMacrophage cellsIntracellular proliferationIntracellular bacteriaKidney fibroblastsVirulence genesFunction mutationsProliferation rateHost cellsBacterial proliferationSerovar TyphimuriumPhoP-PhoQ systemS. entericaProliferationCellsSalmonella enterica