2023
Leveraging the developmental neuroscience of caregiving to promote resilience among youth exposed to adversity
Gee D, Cohodes E. Leveraging the developmental neuroscience of caregiving to promote resilience among youth exposed to adversity. Development And Psychopathology 2023, 35: 2168-2185. PMID: 37929292, PMCID: PMC10872788, DOI: 10.1017/s0954579423001128.Peer-Reviewed Original ResearchCorticolimbic circuitryEmotional functioningYouth emotional functioningEmergence of psychopathologyFavorable mental health outcomesMental health outcomesYouth mental healthEmotion regulationDevelopmental neuroscienceLine of researchNeural mechanismsEarly attachmentEmotional learningEarly adversityFoster resilienceStress reactivityAdversitySensitive periodMental healthClinical interventionsResilienceFunctioningClinical implicationsYouthMajor risk factor
2021
Influences of Caregiving on Development: A Sensitive Period for Biological Embedding of Predictability and Safety Cues
Gee DG, Cohodes EM. Influences of Caregiving on Development: A Sensitive Period for Biological Embedding of Predictability and Safety Cues. Current Directions In Psychological Science 2021, 30: 376-383. PMID: 34675455, PMCID: PMC8528226, DOI: 10.1177/09637214211015673.Peer-Reviewed Original ResearchCorticolimbic circuitryEmotional reactivitySensitive periodCaregiver influenceExternal regulationChildren's emotional reactivityEarly sensitive periodPeriod of plasticityEarly life adversitySafety cuesEmotion regulationNeurobiological mechanismsCaregiving experiencesLife adversityIntervention effortsCaregiver behaviorBehavioral developmentAffective behaviorBiological embeddingHuman researchPowerful influenceAdversityCaregiver inputCaregiversCircuitry
2020
Caregiving influences on emotional learning and regulation: applying a sensitive period model
Gee DG. Caregiving influences on emotional learning and regulation: applying a sensitive period model. Current Opinion In Behavioral Sciences 2020, 36: 177-184. PMID: 33718534, PMCID: PMC7945765, DOI: 10.1016/j.cobeha.2020.11.003.Peer-Reviewed Original ResearchEmotional learningSensitive period modelCorticolimbic circuitrySensitive periodCross-species evidenceExperience-dependent mechanismsEmotional developmentDevelopmental differencesEarly adversityDifferential associationsAdversityLearningConceptual modelDevelopmental timingExperienceSpecific ageAdolescenceCircuitryMaltreatmentChildhoodInfancyAssociationEvidenceCentral roleDifferences
2016
Stimulus-Elicited Connectivity Influences Resting-State Connectivity Years Later in Human Development: A Prospective Study
Gabard-Durnam LJ, Gee DG, Goff B, Flannery J, Telzer E, Humphreys KL, Lumian DS, Fareri DS, Caldera C, Tottenham N. Stimulus-Elicited Connectivity Influences Resting-State Connectivity Years Later in Human Development: A Prospective Study. Journal Of Neuroscience 2016, 36: 4771-4784. PMID: 27122035, PMCID: PMC4846673, DOI: 10.1523/jneurosci.0598-16.2016.Peer-Reviewed Original ResearchConceptsMedial prefrontal cortexFunctional connectivityAmygdala-medial prefrontal cortex circuitInferior frontal gyrusResting-state functional networksFunctional architectureResting-state connectivityAmygdala functional connectivityFunctional network architecturePrefrontal cortex circuitAmygdala-mPFC circuitResting-state networksFunctional connectionsEmotional stimuliCourse of developmentFrontal gyrusAge-related changesPrefrontal cortexMotivate future investigationsCortex circuitPredictive associationsSensitive periodFunctional networksDevelopmental periodBrain function
2015
The impact of developmental timing for stress and recovery
Gee DG, Casey BJ. The impact of developmental timing for stress and recovery. Neurobiology Of Stress 2015, 1: 184-194. PMID: 25798454, PMCID: PMC4363736, DOI: 10.1016/j.ynstr.2015.02.001.Peer-Reviewed Original ResearchEarly life stressTranslational developmental neuroscienceStressful life eventsContext of implicationsImpact of stressDevelopmental neuroscienceStudy of stressResilience factorsEffects of stressLife eventsNeurobiological effectsPositive outcomesSensitive periodBrain changesNovel interventionsBrain developmentAdverse consequencesTiming of stressDevelopmental timingResilienceEarly identificationFunctional outcomeNeurosciencePsychopathologyBrain
2014
Maternal Buffering of Human Amygdala-Prefrontal Circuitry During Childhood but Not During Adolescence
Gee DG, Gabard-Durnam L, Telzer EH, Humphreys KL, Goff B, Shapiro M, Flannery J, Lumian DS, Fareri DS, Caldera C, Tottenham N. Maternal Buffering of Human Amygdala-Prefrontal Circuitry During Childhood but Not During Adolescence. Psychological Science 2014, 25: 2067-2078. PMID: 25280904, PMCID: PMC4377225, DOI: 10.1177/0956797614550878.Peer-Reviewed Original ResearchConceptsAmygdala-prefrontal circuitryMaternal bufferingMaternal stimuliAmygdala-prefrontal connectivityMature connectivityAmygdala reactivityPotential mechanismsMaternal modulationChildhoodMother-child relationshipNeural mechanismsSensitive periodChildrenCaregiversMaternal influenceRegulatory influenceAdolescenceStimuliBehavioral regulationNeurocircuitryCircuitry