Featured Publications
Leveraging the science of stress to promote resilience and optimize mental health interventions during adolescence
Gee DG, Sisk LM, Cohodes EM, Bryce NV. Leveraging the science of stress to promote resilience and optimize mental health interventions during adolescence. Nature Communications 2022, 13: 5693. PMID: 36171218, PMCID: PMC9519553, DOI: 10.1038/s41467-022-33416-4.Peer-Reviewed Original Research
2024
Changes in Frontoamygdala Circuitry Associated With a Parent-Focused Intervention for Pediatric Anxiety Disorders
Gee D, Gunther K, Petrie D, Kitt E, Keding T, Broussard A, Zacharek S, Nardini C, Hommel G, Martino A, Anderson T, Spencer H, Odriozola P, Marin C, Silverman W, Lebowitz E. Changes in Frontoamygdala Circuitry Associated With a Parent-Focused Intervention for Pediatric Anxiety Disorders. Biological Psychiatry 2024, 95: s44. DOI: 10.1016/j.biopsych.2024.02.110.Peer-Reviewed Original Research
2021
Influences of Caregiving on Development: A Sensitive Period for Biological Embedding of Predictability and Safety Cues
Gee DG, Cohodes EM. Influences of Caregiving on Development: A Sensitive Period for Biological Embedding of Predictability and Safety Cues. Current Directions In Psychological Science 2021, 30: 376-383. PMID: 34675455, PMCID: PMC8528226, DOI: 10.1177/09637214211015673.Peer-Reviewed Original ResearchCorticolimbic circuitryEmotional reactivitySensitive periodCaregiver influenceExternal regulationChildren's emotional reactivityEarly sensitive periodPeriod of plasticityEarly life adversitySafety cuesEmotion regulationNeurobiological mechanismsCaregiving experiencesLife adversityIntervention effortsCaregiver behaviorBehavioral developmentAffective behaviorBiological embeddingHuman researchPowerful influenceAdversityCaregiver inputCaregiversCircuitry
2020
Caregiving influences on emotional learning and regulation: applying a sensitive period model
Gee DG. Caregiving influences on emotional learning and regulation: applying a sensitive period model. Current Opinion In Behavioral Sciences 2020, 36: 177-184. PMID: 33718534, PMCID: PMC7945765, DOI: 10.1016/j.cobeha.2020.11.003.Peer-Reviewed Original ResearchEmotional learningSensitive period modelCorticolimbic circuitrySensitive periodCross-species evidenceExperience-dependent mechanismsEmotional developmentDevelopmental differencesEarly adversityDifferential associationsAdversityLearningConceptual modelDevelopmental timingExperienceSpecific ageAdolescenceCircuitryMaltreatmentChildhoodInfancyAssociationEvidenceCentral roleDifferencesInfluences of early‐life stress on frontolimbic circuitry: Harnessing a dimensional approach to elucidate the effects of heterogeneity in stress exposure
Cohodes EM, Kitt ER, Baskin‐Sommers A, Gee DG. Influences of early‐life stress on frontolimbic circuitry: Harnessing a dimensional approach to elucidate the effects of heterogeneity in stress exposure. Developmental Psychobiology 2020, 63: 153-172. PMID: 32227350, DOI: 10.1002/dev.21969.Peer-Reviewed Original ResearchConceptsEarly life stressFrontolimbic circuitryStress exposurePhysical health problemsEffects of stressCircuit maturationGlucocorticoid receptorHealth problemsMajority of studiesMental healthExposure influencePsychobiological effectsDimensional approachEarly experienceDifferential outcomesOutcomesSubsequent vulnerabilityRiskVast heterogeneityExposureInnervationCircuitryBrainSeverityCaregivers
2017
Development of the emotional brain
Casey BJ, Heller AS, Gee DG, Cohen AO. Development of the emotional brain. Neuroscience Letters 2017, 693: 29-34. PMID: 29197573, PMCID: PMC5984129, DOI: 10.1016/j.neulet.2017.11.055.Peer-Reviewed Original ResearchConceptsEmotion reactivityEmotional brainCognitive control circuitryNeurobiological accountsEmotional developmentRecent imaging studiesSelf-RegulationSocial situationsNeural circuitryYoung adulthoodAdolescenceImaging studiesHierarchical changesCircuitryDynamic reorganizationSubcorticoBrainCascade of changesAdulthoodLimbicControl circuitrySituationInstantiationDevelopment
2014
Maternal Buffering of Human Amygdala-Prefrontal Circuitry During Childhood but Not During Adolescence
Gee DG, Gabard-Durnam L, Telzer EH, Humphreys KL, Goff B, Shapiro M, Flannery J, Lumian DS, Fareri DS, Caldera C, Tottenham N. Maternal Buffering of Human Amygdala-Prefrontal Circuitry During Childhood but Not During Adolescence. Psychological Science 2014, 25: 2067-2078. PMID: 25280904, PMCID: PMC4377225, DOI: 10.1177/0956797614550878.Peer-Reviewed Original ResearchConceptsAmygdala-prefrontal circuitryMaternal bufferingMaternal stimuliAmygdala-prefrontal connectivityMature connectivityAmygdala reactivityPotential mechanismsMaternal modulationChildhoodMother-child relationshipNeural mechanismsSensitive periodChildrenCaregiversMaternal influenceRegulatory influenceAdolescenceStimuliBehavioral regulationNeurocircuitryCircuitry