Genetic variation in endocannabinoid signaling is associated with differential network‐level functional connectivity in youth
Sisk LM, Rapuano KM, Conley MI, Greene AS, Horien C, Rosenberg MD, Scheinost D, Constable RT, Glatt CE, Casey BJ, Gee DG. Genetic variation in endocannabinoid signaling is associated with differential network‐level functional connectivity in youth. Journal Of Neuroscience Research 2021, 100: 731-743. PMID: 34496065, PMCID: PMC8866205, DOI: 10.1002/jnr.24946.Peer-Reviewed Original ResearchConceptsEndocannabinoid signalingAllele carriersLower anxiety symptomsC385A polymorphismNetwork-level functional connectivityEnhanced endocannabinoid signalingLarge-scale resting-state brain networksAnxiety symptomsResting-state brain networksGenotype-associated differencesBrain networksFronto-amygdala connectivityFunctional connectionsCognitive Development StudyNetwork-level changesPotential protective factorsAdolescent Brain Cognitive Development (ABCD) studyEndocannabinoid systemNetwork-level differencesYounger ageFunctional connectivityProtective factorsNeural phenotypesAnxiety disordersNeural connectivityEmotion and Emotion Preferences in Daily Life: The Role of Anxiety
Vanderlind WM, Everaert J, Caballero C, Cohodes EM, Gee DG. Emotion and Emotion Preferences in Daily Life: The Role of Anxiety. Clinical Psychological Science 2021, 10: 109-126. PMID: 35174008, PMCID: PMC8845725, DOI: 10.1177/21677026211009500.Peer-Reviewed Original ResearchEmotion preferencesEcological momentary assessmentTrait anxietyLow-anxiety counterpartsSymptom severityAnxiety symptom severityMeasures of anxietyRole of anxietyState emotionsEmotion dysfunctionIndividual differencesSubsequent anxietySevere anxiety symptomsState anxietyAnxiety symptomsMomentary assessmentEmotionsAnxietyCurrent findingsNovel treatment targetsGreater preferenceCurrent studyTreatment targetsDifferent associationsDaily life