2021
Functional Connectivity for the Language Network in the Developing Brain: 30 Weeks of Gestation to 30 Months of Age
Scheinost D, Chang J, Lacadie C, Brennan-Wydra E, Constable RT, Chawarska K, Ment LR. Functional Connectivity for the Language Network in the Developing Brain: 30 Weeks of Gestation to 30 Months of Age. Cerebral Cortex 2021, 32: 3289-3301. PMID: 34875024, PMCID: PMC9340393, DOI: 10.1093/cercor/bhab415.Peer-Reviewed Original ResearchConceptsWeeks of gestationFirst postnatal monthMonths of agePostnatal monthFunctional connectivityWernicke's areaWeeks postmenstrual ageLanguage networkResting-state fMRI dataPostmenstrual ageFetal onsetInterhemispheric connectionsIntrahemispheric connectionsPrimary analysisOlder infantsNeurobehavioral disordersSecondary analysisGestationCross-sectional dataMonthsBrocaUnique participantsWeeksSignificant increaseFunctional connections
2016
Functional magnetic resonance connectivity studies in infants born preterm: suggestions of proximate and long‐lasting changes in language organization
Kwon SH, Scheinost D, Vohr B, Lacadie C, Schneider K, Dai F, Sze G, Constable RT, Ment LR. Functional magnetic resonance connectivity studies in infants born preterm: suggestions of proximate and long‐lasting changes in language organization. Developmental Medicine & Child Neurology 2016, 58: 28-34. PMID: 27027605, PMCID: PMC6426123, DOI: 10.1111/dmcn.13043.Peer-Reviewed Original ResearchLanguage at rest: A longitudinal study of intrinsic functional connectivity in preterm children
Rowlands MA, Scheinost D, Lacadie C, Vohr B, Li F, Schneider KC, Constable R, Ment LR. Language at rest: A longitudinal study of intrinsic functional connectivity in preterm children. NeuroImage Clinical 2016, 11: 149-157. PMID: 26937383, PMCID: PMC4753807, DOI: 10.1016/j.nicl.2016.01.016.Peer-Reviewed Original ResearchConceptsLeft occipito-temporal cortexOccipito-temporal cortexVerbal IQPerformance IQLanguage deficitsSignificant connectivity reductionsPreterm childrenIntrinsic functional connectivityFull IQFunctional connectivity networksFunctional connectivityIQAge 8PT childrenConnectivity reductionLong-range connectionsWorse performanceLinear mixed effects modelsLongitudinal studyConnectivity networksAge 16PT subjectsTS childrenCortical connectivityTerm children
2014
Cerebral Lateralization is Protective in the Very Prematurely Born
Scheinost D, Lacadie C, Vohr BR, Schneider KC, Papademetris X, Constable RT, Ment LR. Cerebral Lateralization is Protective in the Very Prematurely Born. Cerebral Cortex 2014, 25: 1858-1866. PMID: 24451659, PMCID: PMC4459290, DOI: 10.1093/cercor/bht430.Peer-Reviewed Original ResearchConceptsVery preterm participantsPreterm participantsCerebral lateralizationFunctional connectivityPreterm birth altersSevere brain injuryPreterm brainBrain injuryBirth altersTemporal lobeTerm controlsVoxel-based measureDevelopmental delayRight hemisphere lateralizationTerm participantsLateralizationYoung adulthoodSignificant decreaseCerebral asymmetryFurther studiesHemisphere lateralizationLanguage scoresBrainParticipantsAlterations
2012
A left cerebellar pathway mediates language in prematurely-born young adults
Constable RT, Vohr BR, Scheinost D, Benjamin JR, Fulbright RK, Lacadie C, Schneider KC, Katz KH, Zhang H, Papademetris X, Ment LR. A left cerebellar pathway mediates language in prematurely-born young adults. NeuroImage 2012, 64: 371-378. PMID: 22982585, PMCID: PMC3508203, DOI: 10.1016/j.neuroimage.2012.09.008.Peer-Reviewed Original ResearchConceptsPT subjectsTerm controlsInferior frontal gyrusFunctional MRIFunctional connectivityResting-state functional MRIYoung adultsCognitive outcomesSeed-based connectivity analysisAge 20 yearsSeed-based analysisAlternative neural pathwaysControl young adultsPreterm subjectsCerebellar connectivityNeural pathwaysCerebellar pathwaysIndex scoreNineteen ptsGray matterMaternal educationQuadrangular lobuleDevelopmental delayPT brainSignificant positive correlation