2021
Functional connectivity during frustration: a preliminary study of predictive modeling of irritability in youth
Scheinost D, Dadashkarimi J, Finn ES, Wambach CG, MacGillivray C, Roule AL, Niendam TA, Pine DS, Brotman MA, Leibenluft E, Tseng WL. Functional connectivity during frustration: a preliminary study of predictive modeling of irritability in youth. Neuropsychopharmacology 2021, 46: 1300-1306. PMID: 33479511, PMCID: PMC8134471, DOI: 10.1038/s41386-020-00954-8.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAttention Deficit and Disruptive Behavior DisordersAttention Deficit Disorder with HyperactivityChildFrustrationHumansIrritable MoodMood DisordersConceptsFunctional connectivityAttention-deficit/hyperactivity disorderCognitive flexibility taskDisruptive mood dysregulation disorderAffective Reactivity IndexLevels of irritabilityPreliminary fMRI studyCognitive flexibilityFlexibility taskIndividual differencesTransdiagnostic sampleFrontal networkFMRI studyHyperactivity disorderTask difficultyNeural mechanismsParent reportAnxiety symptomsSalience networkAnxiety disordersFrustrative nonrewardDimensional measuresPreliminary evidenceReactivity indexChild psychiatry
2020
Transdiagnostic, Connectome-Based Prediction of Memory Constructs Across Psychiatric Disorders
Barron DS, Gao S, Dadashkarimi J, Greene AS, Spann MN, Noble S, Lake EMR, Krystal JH, Constable RT, Scheinost D. Transdiagnostic, Connectome-Based Prediction of Memory Constructs Across Psychiatric Disorders. Cerebral Cortex 2020, 31: 2523-2533. PMID: 33345271, PMCID: PMC8023861, DOI: 10.1093/cercor/bhaa371.Peer-Reviewed Original ResearchMeSH KeywordsAdultAssociationAttention Deficit Disorder with HyperactivityBipolar DisorderBrainConnectomeFemaleFunctional NeuroimagingHumansMagnetic Resonance ImagingMaleMemoryMemory, Short-TermMental DisordersSchizophreniaSpatial MemoryYoung AdultConceptsMacroscale brain networksIndividual differencesBrain networksMemory deficitsFunctional connectivityAttention deficit hyper-activity disorderTask-based functional MRI dataLong-term memoryWhole-brain functional connectivityDiagnostic groupsWhole-brain patternsDefault mode networkFunctional MRI dataHuman Connectome ProjectPsychiatric disordersMemory constructsMemory performanceTransdiagnostic sampleBrain correlatesMode networkFunctional connectomeConnectome ProjectLimbic networkHealthy participantsMemory
2019
The Functional Brain Organization of an Individual Allows Prediction of Measures of Social Abilities Transdiagnostically in Autism and Attention-Deficit/Hyperactivity Disorder
Lake EMR, Finn ES, Noble SM, Vanderwal T, Shen X, Rosenberg MD, Spann MN, Chun MM, Scheinost D, Constable RT. The Functional Brain Organization of an Individual Allows Prediction of Measures of Social Abilities Transdiagnostically in Autism and Attention-Deficit/Hyperactivity Disorder. Biological Psychiatry 2019, 86: 315-326. PMID: 31010580, PMCID: PMC7311928, DOI: 10.1016/j.biopsych.2019.02.019.Peer-Reviewed Original ResearchMeSH KeywordsAttention Deficit Disorder with HyperactivityAutism Spectrum DisorderCerebral CortexConnectomeFemaleHumansLinear ModelsMagnetic Resonance ImagingMaleNerve NetSocial SkillsConceptsAttention-deficit/hyperactivity disorderAutism spectrum disorderSpectrum disorderFunctional connectivity profilesHyperactivity disorderBrain organizationAutism Brain Imaging Data ExchangeConnectome-based predictive modelingAutism Diagnostic Observation ScheduleAutism spectrum disorder traitsAutism spectrum disorder severitySocial Responsiveness Scale scoresADHD Rating Scale scoresFunctional magnetic resonance imagingBrain-behavior associationsSocial Responsiveness ScaleResting-state functional magnetic resonanceFunctional brain organizationFunctional magnetic resonanceADHD traitsNeurofunctional basisADHD symptomsSplit-half analysisResponsiveness ScaleSocial abilities
2017
Connectome-based predictive modeling of attention: Comparing different functional connectivity features and prediction methods across datasets
Yoo K, Rosenberg MD, Hsu WT, Zhang S, Li CR, Scheinost D, Constable RT, Chun MM. Connectome-based predictive modeling of attention: Comparing different functional connectivity features and prediction methods across datasets. NeuroImage 2017, 167: 11-22. PMID: 29122720, PMCID: PMC5845789, DOI: 10.1016/j.neuroimage.2017.11.010.Peer-Reviewed Original ResearchAdultAttentionAttention Deficit Disorder with HyperactivityBrainConnectomeDatasets as TopicExecutive FunctionHumansMagnetic Resonance ImagingModels, StatisticalPsychomotor PerformanceReproducibility of ResultsYoung Adult
2016
Does prenatal stress alter the developing connectome?
Scheinost D, Sinha R, Cross SN, Kwon SH, Sze G, Constable RT, Ment LR. Does prenatal stress alter the developing connectome? Pediatric Research 2016, 81: 214-226. PMID: 27673421, PMCID: PMC5313513, DOI: 10.1038/pr.2016.197.Peer-Reviewed Original ResearchMeSH KeywordsAnxietyAttention Deficit Disorder with HyperactivityAutism Spectrum DisorderBrainConnectomeDepressive Disorder, MajorFemaleFetal DiseasesHumansMagnetic Resonance ImagingMaleNerve NetNeural PathwaysPregnancyPregnancy ComplicationsRisk FactorsStress, PsychologicalConceptsAttention deficit hyperactivity disorderDeficit hyperactivity disorderStress-related symptomsPrenatal exposureRisk factorsMajor depressionFetal brainMaternal stressPrenatal stressNeural elementsNeurobehavioral disordersFunctional connectivityHyperactivity disorderHuman neurodevelopmentDisordersAutism spectrum disorderFunctional networksConnectomeSpectrum disorderHuman connectomePregnancySymptomsNeurodevelopmentSchizophreniaBrain
2015
A neuromarker of sustained attention from whole-brain functional connectivity
Rosenberg MD, Finn ES, Scheinost D, Papademetris X, Shen X, Constable RT, Chun MM. A neuromarker of sustained attention from whole-brain functional connectivity. Nature Neuroscience 2015, 19: 165-171. PMID: 26595653, PMCID: PMC4696892, DOI: 10.1038/nn.4179.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultAttentionAttention Deficit Disorder with HyperactivityBiomarkersBrainChildConnectomeFemaleHumansInhibition, PsychologicalMagnetic Resonance ImagingMaleModels, NeurologicalNerve NetPsychomotor PerformanceReproducibility of ResultsYoung Adult