1995
Intragenic Domains of Strand-specific Repair inEscherichia coli
Kunala S, Brash D. Intragenic Domains of Strand-specific Repair inEscherichia coli. Journal Of Molecular Biology 1995, 246: 264-272. PMID: 7869378, DOI: 10.1006/jmbi.1994.0082.Peer-Reviewed Original ResearchConceptsTranscription-repair coupling factorTranscription start siteStart siteEscherichia coli genesUV-induced cyclobutane pyrimidine dimersStrand-specific repairMfd mutationExcision repair mechanismChromatin domainsIntragenic domainsGenomic organizationMfd geneColi geneCyclobutane pyrimidine dimersLacZ transcriptionDNA repairInEscherichia coliDownstream domainIndividual nucleotidesRepair mechanismsGenesTranscriptionRepair systemDNA strandsInduced levels
1992
Excision repair at individual bases of the Escherichia coli lacI gene: relation to mutation hot spots and transcription coupling activity.
Kunala S, Brash DE. Excision repair at individual bases of the Escherichia coli lacI gene: relation to mutation hot spots and transcription coupling activity. Proceedings Of The National Academy Of Sciences Of The United States Of America 1992, 89: 11031-11035. PMID: 1438309, PMCID: PMC50477, DOI: 10.1073/pnas.89.22.11031.Peer-Reviewed Original ResearchConceptsTranscribed strandMutation hot spotsChromosomal DNAExcision repairIndividual nucleotidesEscherichia coli chromosomeExcision repair systemColi chromosomeMfd geneDistribution of mutationsGene fragmentsDNA fragmentsEnzymatic incisionCell extractsLacI geneUV-induced mutationsSite of labelingEscherichia coliRepair systemSpecific gene fragmentsUV photoproductsGenesBase variationsMutationsNucleotides
1989
Ultraviolet photoproducts at the ochre suppressor mutation site in the gln U gene of Escherichia coli: Relevance to “mutation frequency decline”
Garvey N, Witkin E, Brash D. Ultraviolet photoproducts at the ochre suppressor mutation site in the gln U gene of Escherichia coli: Relevance to “mutation frequency decline”. Molecular Genetics And Genomics 1989, 219: 359-364. PMID: 2695824, DOI: 10.1007/bf00259607.Peer-Reviewed Original Research
1988
UV MUTAGENIC PHOTOPRODUCTS IN Escherichia coli AND HUMAN CELLS: A MOLECULAR GENETICS PERSPECTIVE ON HUMAN SKIN CANCER*
Brash D. UV MUTAGENIC PHOTOPRODUCTS IN Escherichia coli AND HUMAN CELLS: A MOLECULAR GENETICS PERSPECTIVE ON HUMAN SKIN CANCER*. Photochemistry And Photobiology 1988, 48: 59-66. PMID: 3064116, DOI: 10.1111/j.1751-1097.1988.tb02786.x.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus Statements
1986
The C-C (6-4) UV photoproduct is mutagenic in Escherichia coli.
Glickman BW, Schaaper RM, Haseltine WA, Dunn RL, Brash DE. The C-C (6-4) UV photoproduct is mutagenic in Escherichia coli. Proceedings Of The National Academy Of Sciences Of The United States Of America 1986, 83: 6945-6949. PMID: 3529093, PMCID: PMC386627, DOI: 10.1073/pnas.83.18.6945.Peer-Reviewed Original ResearchSubstrate range of the 40,000-dalton DNA-photoreactivating enzyme from Escherichia coli.
Sutherland B, Oliveira O, Ciarrocchi G, Brash D, Haseltine W, Lewis R, Hanawalt P. Substrate range of the 40,000-dalton DNA-photoreactivating enzyme from Escherichia coli. Biochemistry 1986, 25: 681-7. PMID: 3513832, DOI: 10.1021/bi00351a026.Peer-Reviewed Original Research
1985
Escherichia coli DNA photolyase reverses cyclobutane pyrimidine dimers but not pyrimidine-pyrimidone (6-4) photoproducts.
Brash DE, Franklin WA, Sancar GB, Sancar A, Haseltine WA. Escherichia coli DNA photolyase reverses cyclobutane pyrimidine dimers but not pyrimidine-pyrimidone (6-4) photoproducts. Journal Of Biological Chemistry 1985, 260: 11438-11441. PMID: 3900062, DOI: 10.1016/s0021-9258(17)39046-4.Peer-Reviewed Original ResearchPhotoreactivation of Escherichia coli reverses umuC induction by UV light
Brash DE, Haseltine WA. Photoreactivation of Escherichia coli reverses umuC induction by UV light. Journal Of Bacteriology 1985, 163: 460-463. PMID: 2991189, PMCID: PMC219144, DOI: 10.1128/jb.163.2.460-463.1985.Peer-Reviewed Original Research
1982
UV-induced mutation hotspots occur at DNA damage hotspots
Brash D, Haseltine W. UV-induced mutation hotspots occur at DNA damage hotspots. Nature 1982, 298: 189-192. PMID: 7045692, DOI: 10.1038/298189a0.Peer-Reviewed Original Research