1990
The "microassembly" of integral membrane proteins: applications & implications.
Popot J, Engelman D, Zaccai G, de Vitry C. The "microassembly" of integral membrane proteins: applications & implications. Progress In Clinical And Biological Research 1990, 343: 237-62. PMID: 2198582.Peer-Reviewed Original ResearchConceptsIntegral membrane proteinsMembrane proteinsFunctional integral membrane proteinsMost integral membrane proteinsSingle transmembrane alpha-helixInner membrane complexTransmembrane alpha-helixAutonomous folding domainsInner membraneIntegral subunitThree-dimensional structureTransmembrane regionSequence dataMembrane complexAlpha-helixExtensive rearrangementTertiary structureProteinPolypeptideLipid phasePossible roleOrganellesBiosynthesisSubunitsLocal interactions
1988
Bacteriorhodopsin in and out of Shape: Experimental Evidence in Favor of a Two-Stage Mechanism for Integral Membrane Protein Folding
Popot J, Engelman D. Bacteriorhodopsin in and out of Shape: Experimental Evidence in Favor of a Two-Stage Mechanism for Integral Membrane Protein Folding. Jerusalem Symposia 1988, 21: 381-398. DOI: 10.1007/978-94-009-3075-9_25.Peer-Reviewed Original ResearchIntegral membrane proteinsMembrane proteinsHelical integral membrane proteinsIntegral membrane protein foldingIntegral membrane protein bacteriorhodopsinMembrane protein foldingTransmembrane α-helicesMembrane protein bacteriorhodopsinTransmembrane helicesProtein foldingRenaturation experimentsVesicle fusionExtensive rearrangementNative proteinPolypeptide chainΑ-helixSequence segmentsLipid vesiclesProtein bacteriorhodopsinProteolytic fragmentsProteinFoldingHelixLipid phaseBacteriorhodopsin