2017
Impact of Chronic Total Occlusions on Revascularization Scores and Outcome Prediction.
Redfors B, Palmerini T, Caixeta A, Ayele GM, Francese DP, Mehran R, Brilakis ES, Kirtane AJ, Karmpaliotis D, Stone GW, Généreux P. Impact of Chronic Total Occlusions on Revascularization Scores and Outcome Prediction. Journal Of Invasive Cardiology 2017, 29: 123-131. PMID: 28296639.Peer-Reviewed Original ResearchConceptsSYNTAX scoreChronic total occlusionNon-CTO lesionsCTO lesionsTotal occlusionUrgent Intervention Triage Strategy (ACUITY) trialComplex coronary artery diseaseMajor adverse cardiac eventsMedian SYNTAX scoreOverall SYNTAX scoreAdverse cardiac eventsCoronary artery diseaseAcute CatheterizationAngiographic substudyRevascularization scoresCardiac eventsRevascularization strategyArtery diseaseStrategy trialPatientsTraditional SSLesionsOutcome predictionRisk predictionSubstantial proportion
2015
Risk stratification of patients undergoing medical therapy after coronary angiography
Bettinger N, Palmerini T, Caixeta A, Dressler O, Litherland C, Francese DP, Giustino G, Mehran R, Leon MB, Stone GW, Généreux P. Risk stratification of patients undergoing medical therapy after coronary angiography. European Heart Journal 2015, 37: 3103-3110. PMID: 26685136, DOI: 10.1093/eurheartj/ehv674.Peer-Reviewed Original ResearchConceptsMajor adverse cardiac eventsCoronary artery diseaseSYNTAX scoreMedical therapyNSTE-ACSRisk stratificationSegment elevation acute coronary syndromesElevation acute coronary syndromeAdverse ischemic eventsMean SYNTAX scoreAdverse cardiac eventsAcute coronary syndromeBetter prognostic accuracyReceiver operator characteristic analysisImportant clinical implicationsStrongest predictorOperator characteristic analysisACUITY trialCoronary syndromeInitial angiogramCardiac eventsIschemic eventsPrognostic impactArtery diseaseCoronary angiographyReasonable incomplete revascularisation after percutaneous coronary intervention: the SYNTAX Revascularisation Index.
Généreux P, Campos CM, Yadav M, Palmerini T, Caixeta A, Xu K, Francese DP, Dangas GD, Mehran R, Leon MB, Serruys PW, Stone GW. Reasonable incomplete revascularisation after percutaneous coronary intervention: the SYNTAX Revascularisation Index. EuroIntervention 2015, 11: 634-42. PMID: 25308300, DOI: 10.4244/eijy14m10_05.Peer-Reviewed Original ResearchMeSH KeywordsAgedArea Under CurveChi-Square DistributionCoronary AngiographyCoronary Artery DiseaseDecision Support TechniquesFemaleHumansKaplan-Meier EstimateMaleMiddle AgedMultivariate AnalysisMyocardial InfarctionPercutaneous Coronary InterventionPredictive Value of TestsProportional Hazards ModelsProspective StudiesRisk AssessmentRisk FactorsROC CurveTime FactorsTreatment OutcomeConceptsResidual SYNTAX scorePercutaneous coronary interventionBaseline SYNTAX scoreOne-year mortalityCoronary artery diseaseCAD burdenIncomplete revascularisationSYNTAX scoreCoronary interventionOne-year adverse outcomesResidual coronary artery diseaseNew prognostic instrumentPrediction of deathAngiograms of patientsBetter prognostic accuracyDegree of revascularisationACUITY trialArtery diseaseIndependent predictorsMultivariable analysisAdverse outcomesWorse outcomesPrognostic accuracyPrognostic instrumentPatientsThe association between the extent of coronary artery disease and major bleeding events after percutaneous coronary intervention: from the ACUITY trial.
Madhavan MV, Généreux P, Palmerini T, Caixeta A, Xu K, McAndrew TC, Francese DP, Kirtane AJ, Mehran R, Stone GW. The association between the extent of coronary artery disease and major bleeding events after percutaneous coronary intervention: from the ACUITY trial. Journal Of Invasive Cardiology 2015, 27: 203-11. PMID: 25840404.Peer-Reviewed Original ResearchMeSH KeywordsAcute Coronary SyndromeAgedCoronary AngiographyCoronary Artery BypassCoronary Artery DiseaseFemaleHumansMaleMiddle AgedMulticenter Studies as TopicMultivariate AnalysisPercutaneous Coronary InterventionPostoperative HemorrhageProportional Hazards ModelsProspective StudiesRandomized Controlled Trials as TopicRisk FactorsConceptsNon-ST segment elevation acute coronary syndromesPercutaneous coronary interventionCoronary artery diseaseExtent of CADMajor bleeding ratesSYNTAX scoreACUITY trialMajor bleedingCoronary interventionArtery diseaseBleeding rateSegment elevation acute coronary syndromesSeverity of CADElevation acute coronary syndromeSevere coronary artery diseaseAdverse ischemic eventsMajor bleeding eventsAcute coronary syndromeCommon risk factorsRecurrent adverse eventsBleeding eventsPCI cohortSS tertilesCoronary syndromeHemorrhagic events