2023
Impact of New‐Onset Conduction Disturbances following Transcatheter Aortic Valve Replacement on Outcomes: A Single‐Center Study
See C, Wang Y, Huang H, Parise H, Yang Y, Tirziu D, Francese D, Papoutsidakis N, Bader E, Kaple R, Cleman M, Lansky A, Forrest J. Impact of New‐Onset Conduction Disturbances following Transcatheter Aortic Valve Replacement on Outcomes: A Single‐Center Study. Journal Of Interventional Cardiology 2023, 2023: 5390338. PMID: 37292113, PMCID: PMC10247319, DOI: 10.1155/2023/5390338.Peer-Reviewed Original ResearchConceptsTranscatheter aortic valve replacementNew-onset conduction disturbancesAortic valve replacementPersistent conduction disturbancesConduction disturbancesValve replacementSurgical aortic valve replacementSingle-center retrospective analysisYale-New Haven HospitalSingle-center studyCause mortality ratesCause mortality riskLong-term outcomesNew Haven HospitalPeriprocedural factorsAortic stenosisConsecutive patientsTAVR proceduresTerm outcomesRetrospective analysisMortality riskMortality ratePatientsOutcomesPatient's ECG
2020
COVID-19 and Thrombotic or Thromboembolic Disease: Implications for Prevention, Antithrombotic Therapy, and Follow-Up JACC State-of-the-Art Review
Bikdeli B, Madhavan MV, Jimenez D, Chuich T, Dreyfus I, Driggin E, Der Nigoghossian C, Ageno W, Madjid M, Guo Y, Tang LV, Hu Y, Giri J, Cushman M, Quéré I, Dimakakos EP, Gibson CM, Lippi G, Favaloro EJ, Fareed J, Caprini JA, Tafur AJ, Burton JR, Francese DP, Wang EY, Falanga A, McLintock C, Hunt BJ, Spyropoulos AC, Barnes GD, Eikelboom JW, Weinberg I, Schulman S, Carrier M, Piazza G, Beckman JA, Steg PG, Stone GW, Rosenkranz S, Goldhaber SZ, Parikh SA, Monreal M, Krumholz HM, Konstantinides SV, Weitz JI, Lip GYH, Global COVID-19 Thrombosis Collaborative Group E. COVID-19 and Thrombotic or Thromboembolic Disease: Implications for Prevention, Antithrombotic Therapy, and Follow-Up JACC State-of-the-Art Review. Journal Of The American College Of Cardiology 2020, 75: 2950-2973. PMID: 32311448, PMCID: PMC7164881, DOI: 10.1016/j.jacc.2020.04.031.Peer-Reviewed Original ResearchConceptsAntithrombotic therapyThrombotic diseaseCOVID-19Outcomes of patientsViral respiratory illnessEndothelial dysfunctionArterial thrombosisThromboembolic diseaseExcessive inflammationRespiratory illnessLaboratory monitoringJACC StateArterial circulationPlatelet activationPatientsCoronavirus diseaseDiseaseTherapyCOVID-19 pandemicPreventionCurrent understandingThromboticThrombosisInflammationDysfunction
2017
Impact of Chronic Total Occlusions on Revascularization Scores and Outcome Prediction.
Redfors B, Palmerini T, Caixeta A, Ayele GM, Francese DP, Mehran R, Brilakis ES, Kirtane AJ, Karmpaliotis D, Stone GW, Généreux P. Impact of Chronic Total Occlusions on Revascularization Scores and Outcome Prediction. Journal Of Invasive Cardiology 2017, 29: 123-131. PMID: 28296639.Peer-Reviewed Original ResearchConceptsSYNTAX scoreChronic total occlusionNon-CTO lesionsCTO lesionsTotal occlusionUrgent Intervention Triage Strategy (ACUITY) trialComplex coronary artery diseaseMajor adverse cardiac eventsMedian SYNTAX scoreOverall SYNTAX scoreAdverse cardiac eventsCoronary artery diseaseAcute CatheterizationAngiographic substudyRevascularization scoresCardiac eventsRevascularization strategyArtery diseaseStrategy trialPatientsTraditional SSLesionsOutcome predictionRisk predictionSubstantial proportion
2016
Dedicated Bifurcation Stent for the Treatment of Bifurcation Lesions Involving Large Side Branches Outcomes From the Tryton Confirmatory Study
Généreux P, Kumsars I, Schneider JE, Lesiak M, Redfors B, Cornelis K, Selmon MR, Dens J, Hoye A, Metzger DC, Muyldermans L, Slagboom T, Francese DP, Ayele GM, Laak LL, Bartorelli AL, Cutlip DE, Kaplan AV, Leon MB. Dedicated Bifurcation Stent for the Treatment of Bifurcation Lesions Involving Large Side Branches Outcomes From the Tryton Confirmatory Study. JACC Cardiovascular Interventions 2016, 9: 1338-1346. PMID: 27388820, DOI: 10.1016/j.jcin.2016.03.042.Peer-Reviewed Original ResearchMeSH KeywordsAgedAngioplasty, Balloon, CoronaryBiomarkersChromium AlloysCoronary AngiographyCoronary Artery DiseaseCoronary StenosisCoronary VesselsCreatine Kinase, MB FormEuropeFemaleHumansMaleMiddle AgedMyocardial InfarctionProspective StudiesProsthesis DesignRisk FactorsStentsTime FactorsTreatment OutcomeUnited StatesConceptsTryton Side Branch StentPeriprocedural myocardial infarctionSide Branch StentPivotal RCTsLarge side branchesPrimary endpointMyocardial infarctionBranch StentConfirmatory studiesBifurcation lesionsSide branchesProvisional side branchDedicated bifurcation stentsStent armOnly patientsAngiographic parametersCoronary artery bifurcationsPatientsRCTsSmall side branchesInfarctionOverall trialBifurcation stentsArtery bifurcationPre-defined performance goal
2015
Reasonable incomplete revascularisation after percutaneous coronary intervention: the SYNTAX Revascularisation Index.
Généreux P, Campos CM, Yadav M, Palmerini T, Caixeta A, Xu K, Francese DP, Dangas GD, Mehran R, Leon MB, Serruys PW, Stone GW. Reasonable incomplete revascularisation after percutaneous coronary intervention: the SYNTAX Revascularisation Index. EuroIntervention 2015, 11: 634-42. PMID: 25308300, DOI: 10.4244/eijy14m10_05.Peer-Reviewed Original ResearchMeSH KeywordsAgedArea Under CurveChi-Square DistributionCoronary AngiographyCoronary Artery DiseaseDecision Support TechniquesFemaleHumansKaplan-Meier EstimateMaleMiddle AgedMultivariate AnalysisMyocardial InfarctionPercutaneous Coronary InterventionPredictive Value of TestsProportional Hazards ModelsProspective StudiesRisk AssessmentRisk FactorsROC CurveTime FactorsTreatment OutcomeConceptsResidual SYNTAX scorePercutaneous coronary interventionBaseline SYNTAX scoreOne-year mortalityCoronary artery diseaseCAD burdenIncomplete revascularisationSYNTAX scoreCoronary interventionOne-year adverse outcomesResidual coronary artery diseaseNew prognostic instrumentPrediction of deathAngiograms of patientsBetter prognostic accuracyDegree of revascularisationACUITY trialArtery diseaseIndependent predictorsMultivariable analysisAdverse outcomesWorse outcomesPrognostic accuracyPrognostic instrumentPatients