2001
Cellular trafficking in trypanosomatids: a new target for therapies?
Costa-Pinto D, Trindade L, McMahon-Pratt D, Traub-Cseko Y. Cellular trafficking in trypanosomatids: a new target for therapies? International Journal For Parasitology 2001, 31: 537-544. PMID: 11334939, DOI: 10.1016/s0020-7519(01)00145-x.Peer-Reviewed Original ResearchConceptsPathogenic trypanosomatidsTrafficking mechanismsLysosomal targetingCellular trafficking mechanismsPlethora of diseasesCellular traffickingTrypanosomatidsTargeting mechanismCysteine proteinasesBiological aspectsNew targetsCurrent knowledgeEfficient vaccineDisease controlTherapyBasic mechanismsTraffickingMechanismTargetParasitesVaccineProteinasesDiseaseTargeting
1990
Evolution of nuclear DNA and the occurrence of sequences related to new small chromosomal DNAs in the trypanosomatid genus Endotrypanum
de C.S. Lopes A, Iovannisci D, Petrillo-Peixoto M, McMahon-Pratt D, Beverley S. Evolution of nuclear DNA and the occurrence of sequences related to new small chromosomal DNAs in the trypanosomatid genus Endotrypanum. Molecular And Biochemical Parasitology 1990, 40: 151-161. PMID: 2362601, DOI: 10.1016/0166-6851(90)90037-m.Peer-Reviewed Original ResearchConceptsHybridization probesMolecular karyotype analysisMolecular evolutionary treeComplex hybridization patternDNA restriction fragment patternsRestriction fragment patternsEvolutionary relatednessSequence divergenceDisjunct distributionEvolutionary treeTrypanosomatid parasitesGenus EndotrypanumNuclear DNAChromosomal DNAHybridization patternsRelated sequencesRestriction enzymesChromosomesEndotrypanumFragment patternsKaryotype analysisOccurrence of sequencesDNAGroup B isolatesVirus-like particles