2024
Biomarker Panels for Predicting Progression of Kidney Disease in Acute Kidney Injury Survivors.
Menez S, Kerr K, Cheng S, Hu D, Thiessen-Philbrook H, Moledina D, Mansour S, Go A, Ikizler T, Kaufman J, Kimmel P, Himmelfarb J, Coca S, Parikh C. Biomarker Panels for Predicting Progression of Kidney Disease in Acute Kidney Injury Survivors. Clinical Journal Of The American Society Of Nephrology 2024 PMID: 39671257, DOI: 10.2215/cjn.0000000622.Peer-Reviewed Original ResearchAcute kidney injurySoluble tumor necrosis factor receptor 1End-stage kidney diseaseChronic kidney diseaseKidney diseaseFollow-upPost-AKI careDevelopment of end-stage kidney diseaseKidney-specific outcomesYears of follow-upCombination of clinical variablesReceiver-operating characteristic curveTumor necrosis factor receptor 1Progression of kidney diseaseSequelae of acute kidney injuryAdverse kidney eventsAge of study participantsAcute kidney injury survivorsDiuretic useEGFR declineKidney disease riskKidney eventsAKI patientsKidney injuryPost-discharge follow-up
2021
Urinary EGF and MCP-1 and risk of CKD after cardiac surgery
Menez S, Ju W, Menon R, Moledina DG, Thiessen Philbrook H, McArthur E, Jia Y, Obeid W, Mansour SG, Koyner JL, Shlipak MG, Coca SG, Garg AX, Bomback AS, Kellum JA, Kretzler M, Parikh CR, . Urinary EGF and MCP-1 and risk of CKD after cardiac surgery. JCI Insight 2021, 6: e147464. PMID: 33974569, PMCID: PMC8262289, DOI: 10.1172/jci.insight.147464.Peer-Reviewed Original ResearchMeSH KeywordsAcute Kidney InjuryAgedAged, 80 and overCardiac Surgical ProceduresChemokine CCL2Disease ProgressionEpidermal Growth FactorFemaleGene Expression ProfilingHumansIncidenceMalePostoperative ComplicationsProportional Hazards ModelsRenal Insufficiency, ChronicRNA, MessengerRNA-SeqSingle-Cell AnalysisConceptsAcute kidney injuryCardiac surgeryMCP-1CKD outcomesUrinary EGFLong-term kidney outcomesChronic kidney disease riskTRIBE-AKI (Translational Research Investigating Biomarker Endpoints for Acute Kidney Injury) ConsortiumKidney disease riskMCP-1 levelsRisk of CKDAmerican Heart AssociationPostoperative urine samplesHealth Research InstituteLong-term careCKD incidenceKidney outcomesKidney injuryKidney Precision Medicine ProjectComposite outcomeTubular damageHeart AssociationCCL2 expressionGlomerular functionKidney Center