Molecular and behavioral mechanisms mediating paclitaxel‐induced changes in affect‐like behavior in mice
Meade J, Toma W, Alkhlaif Y, Bagdas D, Obeng S, Selley D, Damaj M. Molecular and behavioral mechanisms mediating paclitaxel‐induced changes in affect‐like behavior in mice. The FASEB Journal 2019, 33: 807.1-807.1. DOI: 10.1096/fasebj.2019.33.1_supplement.807.1.Peer-Reviewed Original ResearchKappa-opioid receptorsPaclitaxel-induced changesDepression-like behaviorInjection of vehicleNucleus accumbensSucrose preferenceRole of KORSelective KOR antagonist norbinaltorphimineDopamine D 2 receptorsKOR antagonist norbinaltorphimineTreatment-resistant depressionFemale C57BL/6J miceQuality of lifeFull-text articlesBaby boomer populationCancer survivorsAntagonist norbinaltorphimineC57BL/6J miceOpioid receptorsCancer ageKOR agonistsNeurochemical targetsTherapeutic interventionsPalatable foodProdynorphin mRNA