Genotoxic and Anti-Genotoxic Effects of Vanillic Acid Against Mitomycin C-Induced Genomic Damage in Human Lymphocytes In Vitro
Erdem M, Cinkilic N, Vatan O, Yilmaz D, Bagdas D, Bilaloglu R. Genotoxic and Anti-Genotoxic Effects of Vanillic Acid Against Mitomycin C-Induced Genomic Damage in Human Lymphocytes In Vitro. Asian Pacific Journal Of Cancer Prevention 2012, 13: 4993-4998. PMID: 23244097, DOI: 10.7314/apjcp.2012.13.10.4993.Peer-Reviewed Original ResearchConceptsAnti-genotoxic effectsMitomycin CHuman blood lymphocyte culturesCytokinesis-block micronucleus testBlood lymphocyte culturesLow doseHigh doseLymphocyte culturesHuman lymphocytesMicronucleus testAlkaline cometDoseGenotoxic damageGenotoxic effectsStrong antioxidantNegative controlOxidative damageGenomic damageVanillic acidChromosome levelPresent studyRates of DNADNA damageDamageSimilar results