Effects of Adrenomedullin and Glucagon-like Peptide on Distal Flap Necrosis and Vascularity: The Role of Receptor Systems and Nitric Oxide.
Cam B, Bagdas D, Ozyigit M, Sagdilek E, Buyukcoskun N, Ozluk K. Effects of Adrenomedullin and Glucagon-like Peptide on Distal Flap Necrosis and Vascularity: The Role of Receptor Systems and Nitric Oxide. WOUNDS A Compendium Of Clinical Research And Practice 2017, 29: 163-167. PMID: 28355142.Peer-Reviewed Original ResearchMeSH KeywordsAdrenomedullinAnimalsAntioxidantsCalcitonin Gene-Related PeptideDisease Models, AnimalEpigastric ArteriesFemaleGlucagon-Like Peptide ReceptorsGlucagon-Like PeptidesGraft SurvivalImmunohistochemistryNecrosisNitric OxideRatsRats, WistarReceptors, Calcitonin Gene-Related PeptideSurgical FlapsWound HealingWounds and InjuriesConceptsGlucagon-like peptide-1Superficial inferior epigastric arteryEffects of adrenomedullinFlap healingNitric oxideFlap necrosisReceptor antagonistNecrosis areaGLP-1 receptor antagonistCalcitonin gene-related peptide receptorAdult female Wistar ratsGene-related peptide receptorBeneficial effectsADM receptor antagonistAdministration of adrenomedullinPostoperative day 7Inferior epigastric arteryGLP-1 receptorDistal flap necrosisFemale Wistar ratsGlucagon-like peptideMajor complicationsCGRP receptorsEpigastric arteryWistar rats