2011
Glycine Transporter Inhibitor Attenuates the Psychotomimetic Effects of Ketamine in Healthy Males: Preliminary Evidence
D'Souza DC, Singh N, Elander J, Carbuto M, Pittman B, de Haes J, Sjogren M, Peeters P, Ranganathan M, Schipper J. Glycine Transporter Inhibitor Attenuates the Psychotomimetic Effects of Ketamine in Healthy Males: Preliminary Evidence. Neuropsychopharmacology 2011, 37: 1036-1046. PMID: 22113087, PMCID: PMC3280648, DOI: 10.1038/npp.2011.295.Peer-Reviewed Original Research
2001
Comment on “ketamine has equal affinity for NMDA receptors and the high-affinity state of the dopamine D2 receptor”
Krystal J, D’Souza D. Comment on “ketamine has equal affinity for NMDA receptors and the high-affinity state of the dopamine D2 receptor”. Biological Psychiatry 2001, 50: 555. PMID: 11600110, DOI: 10.1016/s0006-3223(01)01258-6.Peer-Reviewed Original Research
2000
Dissociation of ketamine effects on rule acquisition and rule implementation: possible relevance to NMDA receptor contributions to executive cognitive functions
Krystal J, Bennett A, Abi-Saab D, Belger A, Karper L, D’Souza D, Lipschitz D, Abi-Dargham A, Charney D. Dissociation of ketamine effects on rule acquisition and rule implementation: possible relevance to NMDA receptor contributions to executive cognitive functions. Biological Psychiatry 2000, 47: 137-143. PMID: 10664830, PMCID: PMC10060085, DOI: 10.1016/s0006-3223(99)00097-9.Peer-Reviewed Original ResearchMeSH KeywordsAdultAnesthetics, DissociativeArousalCognition DisordersFemaleHumansKetamineLearningMaleNeuropsychological TestsPsychomotor PerformanceReceptors, N-Methyl-D-AspartateConceptsExecutive cognitive functionSecond test dayPerseverative errorsWCST performanceCognitive functionTest daySecond studyExecutive componentTask repetitionAltered perceptionWCSTNMDA antagonist ketamineNegative symptomsFrontal cortexRule acquisitionTest changesFirst studySingle repetitionKetamine effectsRepetitionTotal errorDistractibilityReceptor contributionNMDA receptor contributionRecall
1999
Interactive effects of subanesthetic ketamine and haloperidol in healthy humans
Krystal J, D’Souza D, Karper L, Bennett A, Abi-Dargham A, Abi-Saab D, Cassello K, Bowers Jr. M, Vegso S, Heninger G, Charney D, Bowers M. Interactive effects of subanesthetic ketamine and haloperidol in healthy humans. Psychopharmacology 1999, 145: 193-204. PMID: 10463321, DOI: 10.1007/s002130051049.Peer-Reviewed Original Research
1998
The NMDA Antagonist Model for Schizophrenia: Promise and Pitfalls
Abi-Saab W, D'Souza D, Moghaddam B, Krystal J. The NMDA Antagonist Model for Schizophrenia: Promise and Pitfalls. Pharmacopsychiatry 1998, 31: 104-109. PMID: 9754841, DOI: 10.1055/s-2007-979354.Peer-Reviewed Original ResearchAnesthetics, DissociativeExcitatory Amino Acid AntagonistsHumansKetamineReceptors, N-Methyl-D-AspartateSchizophrenia