2024
A Survey of Patient Experience During Molecular Breast Imaging
Hruska C, Gray L, Jenkins S, Block E, Hunt K, Conners A, Zingula S, O'Connor M, Rhodes D. A Survey of Patient Experience During Molecular Breast Imaging. Journal Of Nuclear Medicine Technology 2024, 52: jnmt.123.266856. PMID: 38839120, PMCID: PMC11149590, DOI: 10.2967/jnmt.123.266856.Peer-Reviewed Original ResearchPatient experiencePersonal history of breast cancerDense breastsSurvey of patient experienceHistory of breast cancerPositive patient experienceAssociated with respondents' ageImprove patient experienceSoliciting patient feedbackPatient comfort levelMammographically dense breastsPatient feedbackStudy consentMolecular breast imagingNeck discomfortRespondents' agePersonal historyMammographyComfort levelSource of discomfortBreast compressionBreast cancerEvaluating patientsInfluence willingnessRespondents
2023
Breast Cancer Mode of Detection in a Population-Based Cohort
Basappa S, Finney Rutten L, Hruska C, Olson J, Jacobson D, Rhodes D. Breast Cancer Mode of Detection in a Population-Based Cohort. Mayo Clinic Proceedings 2023, 98: 278-289. PMID: 36737116, PMCID: PMC9907001, DOI: 10.1016/j.mayocp.2022.10.010.Peer-Reviewed Original ResearchConceptsPopulation-based cohortBreast cancerAdvanced cancerBreast densityRetrospective medical record reviewDense breastsPositive lymph nodesFirst-time diagnosisRochester Epidemiology ProjectMedical record reviewStage of diseaseLarger tumor sizeWomen age 40High-grade tumorsMultiple logistic regressionYears of ageLymph nodesRecord reviewTumor characteristicsTumor sizeCancer characteristicsCancer modeAge 40Clinical attentionCancer
2021
Background Parenchymal Uptake on Molecular Breast Imaging and Breast Cancer Risk: A Cohort Study.
Hruska CB, Geske JR, Conners AL, Whaley DH, Rhodes DJ, O'Connor MK, Carter RE, Scott CG, Vachon CM. Background Parenchymal Uptake on Molecular Breast Imaging and Breast Cancer Risk: A Cohort Study. American Journal Of Roentgenology 2021, 216: 1193-1204. PMID: 32755210, PMCID: PMC8640999, DOI: 10.2214/ajr.20.23854.Peer-Reviewed Original ResearchConceptsBackground parenchymal uptakeMolecular breast imagingPostmenopausal womenBreast cancer riskAbsolute riskBreast cancerCohort studyDiscriminatory accuracyDense breastsRisk factorsParenchymal uptakeCancer riskRisk scoreFuture breast cancer diagnosisGreater breast cancer riskBreast cancer risk factorsCox proportional hazards modelGail risk scoreBreast cancer eventsIndependent risk factorSubset of womenCancer risk factorsCase-control studyProportional hazards modelBreast cancer diagnosisComparison of Universal Genetic Testing vs Guideline-Directed Targeted Testing for Patients With Hereditary Cancer Syndrome
Samadder N, Riegert-Johnson D, Boardman L, Rhodes D, Wick M, Okuno S, Kunze K, Golafshar M, Uson P, Mountjoy L, Ertz-Archambault N, Patel N, Rodriguez E, Lizaola-Mayo B, Lehrer M, Thorpe C, Yu N, Esplin E, Nussbaum R, Sharp R, Azevedo C, Klint M, Hager M, Macklin-Mantia S, Bryce A, Bekaii-Saab T, Sekulic A, Stewart A. Comparison of Universal Genetic Testing vs Guideline-Directed Targeted Testing for Patients With Hereditary Cancer Syndrome. JAMA Oncology 2021, 7: 230-237. PMID: 33126242, PMCID: PMC7600058, DOI: 10.1001/jamaoncol.2020.6252.Peer-Reviewed Original ResearchConceptsPrevalence of pathogenic germline variantsFamily variant testingPathogenic germline variantsSolid tumor cancersHigh-penetrance cancer susceptibility genesFamily history of cancerMayo Clinic Cancer CenterRisk-reducing interventionsUniversal genetic testingMultigene panel testingHigh-penetrance variantsHistory of cancerClinic Cancer CenterUniversal testing approachGermline variantsGuideline-directed approachYounger age of diagnosisTumor cancersCancer susceptibility genesClinically actionable findingsTargeted testingCancer screeningAge of diagnosisGermline testingVariant testing
2020
Comment on “Radiation Doses and Risks in Breast Screening”
Conners A, Ellis R, Fazzio R, Hruska C, Hunt K, O’Connor M, Rhodes D, Shermis R. Comment on “Radiation Doses and Risks in Breast Screening”. Journal Of Breast Imaging 2020, 2: 519-520. PMID: 38424854, DOI: 10.1093/jbi/wbaa074.Peer-Reviewed Original ResearchEvaluation of Germline Genetic Testing Criteria in a Hospital-Based Series of Women With Breast Cancer.
Yadav S, Hu C, Hart SN, Boddicker N, Polley EC, Na J, Gnanaolivu R, Lee KY, Lindstrom T, Armasu S, Fitz-Gibbon P, Ghosh K, Stan DL, Pruthi S, Neal L, Sandhu N, Rhodes DJ, Klassen C, Peethambaram PP, Haddad TC, Olson JE, Hoskin TL, Goetz MP, Domchek SM, Boughey JC, Ruddy KJ, Couch FJ. Evaluation of Germline Genetic Testing Criteria in a Hospital-Based Series of Women With Breast Cancer. Journal Of Clinical Oncology : Official Journal Of The American Society Of Clinical Oncology 2020, 38: 1409-1418. PMID: 32125938, PMCID: PMC7193748, DOI: 10.1200/JCO.19.02190.Peer-Reviewed Original ResearchEffect of a 12-Week Pilates Pelvic Floor-Strengthening Program on Short-Term Measures of Stress Urinary Incontinence in Women: A Pilot Study
Hein JT, Rieck TM, Dunfee HA, Johnson DP, Ferguson JA, Rhodes DJ. Effect of a 12-Week Pilates Pelvic Floor-Strengthening Program on Short-Term Measures of Stress Urinary Incontinence in Women: A Pilot Study. Journal Of Alternative And Complementary Medicine 2020, 26: 158-161. PMID: 31916840, PMCID: PMC7044776, DOI: 10.1089/acm.2019.0330.Peer-Reviewed Original ResearchSupplemental screening in the dense breast: does molecular breast imaging have a role?
Rhodes DJ. Supplemental screening in the dense breast: does molecular breast imaging have a role? Menopause The Journal Of The North American Menopause Society 2020, 27: 110-112. PMID: 31880677, DOI: 10.1097/gme.0000000000001471.Peer-Reviewed Original Research
2019
Behavioral and psychological impact of returning breast density results to Latinas: study protocol for a randomized clinical trial
Patel BK, Ridgeway JL, Ghosh K, Rhodes DJ, Borah B, Jenkins S, Suman VJ, Norman A, Jewett M, Singh D, Vachon CM, Radecki Breitkopf C. Behavioral and psychological impact of returning breast density results to Latinas: study protocol for a randomized clinical trial. Trials 2019, 20: 744. PMID: 31852492, PMCID: PMC6921571, DOI: 10.1186/s13063-019-3939-6.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedAnxietyBreast DensityBreast NeoplasmsEarly Detection of CancerFemaleHealth CommunicationHealth Knowledge, Attitudes, PracticeHealth LiteracyHispanic or LatinoHumansMammographyMass ScreeningMiddle AgedPatient CompliancePatient Education as TopicQualitative ResearchRandomized Controlled Trials as TopicConceptsRandomized clinical trialsMammographic breast densityLimited resource settingsClinical trialsHealth literacyBreast densityWHO Trial Registration Data SetLatina womenTrial Registration Data SetLimited health literacyLow health literacyBreast cancer riskCancer risk communicationPsychological outcomesMeasurement time pointsDiagnostic delayCancer mortalityBackgroundBreast cancerCommon cancerMammogram resultsStudy protocolCommunity clinicsBreast cancerMammography screeningCancer riskBreast Density Awareness, Knowledge, and Attitudes Among US Women: National Survey Results Across 5 Years
Rhodes DJ, Jenkins SM, Hruska CB, Vachon CM, Breitkopf CR. Breast Density Awareness, Knowledge, and Attitudes Among US Women: National Survey Results Across 5 Years. Journal Of The American College Of Radiology 2019, 17: 391-404. PMID: 31756308, DOI: 10.1016/j.jacr.2019.11.003.Peer-Reviewed Original ResearchMolecular Breast Imaging in Patients with Suspicious Calcifications
Hunt K, Hruska C, Johnson M, Conners A, O’connor M, Rhodes D, Basappa S, Wahner-Roedler D. Molecular Breast Imaging in Patients with Suspicious Calcifications. Journal Of Breast Imaging 2019, 1: 303-309. PMID: 38424809, DOI: 10.1093/jbi/wbz054.Peer-Reviewed Original ResearchMolecular breast imagingSuspicious calcificationsNegative predictive valueTelluride gamma cameraPredictive valueMedian pathologic sizeInvasive ductal cancerOccult breast cancerInjection of TcAreas of calcificationBreast imagingNuclear medicine techniquesPrebiopsy settingGamma cameraBiopsy findingsDuctal cancerPathologic sizeIncidental lesionsDuctal carcinomaInvasive cancerAdditional biopsiesBreast cancerStereotactic biopsyBiopsyMolecular breastDose Reduction in Molecular Breast Imaging With a New Image-Processing Algorithm.
Tao AT, Hruska CB, Conners AL, Hunt KN, Swanson TN, Tran TD, Manduca A, Borges L, Maidment ADA, Lake D, Johnson MP, Carter RE, Rhodes DJ, O'Connor MK. Dose Reduction in Molecular Breast Imaging With a New Image-Processing Algorithm. American Journal Of Roentgenology 2019, 214: 185-193. PMID: 31593516, DOI: 10.2214/ajr.19.21582.Peer-Reviewed Original ResearchImpact of short-term low-dose tamoxifen on molecular breast imaging background parenchymal uptake: a pilot study
Hruska CB, Hunt KN, Conners AL, Geske JR, Brandt KR, Degnim AC, Vachon CM, O’Connor M, Rhodes DJ. Impact of short-term low-dose tamoxifen on molecular breast imaging background parenchymal uptake: a pilot study. Breast Cancer Research 2019, 21: 38. PMID: 30850011, PMCID: PMC6408779, DOI: 10.1186/s13058-019-1120-5.Peer-Reviewed Original ResearchConceptsLow-dose tamoxifenMolecular breast imagingBackground parenchymal uptakeOral tamoxifenParenchymal uptakeBreast cancer risk reductionBreast cancer risk factorsEffectiveness of tamoxifenCancer risk factorsCancer risk reductionBreast cancer historyShort-term interventionMean ageCancer historyRisk factorsBreast fibroglandular tissueTamoxifenMolecular breastAverage countStudy participantsSubcutaneous fatPilot studyWomenT-testInterventionClassification of Background Parenchymal Uptake on Molecular Breast Imaging Using a Convolutional Neural Network
Carter RE, Attia ZI, Geske JR, Conners AL, Whaley DH, Hunt KN, O’Connor M, Rhodes DJ, Hruska CB. Classification of Background Parenchymal Uptake on Molecular Breast Imaging Using a Convolutional Neural Network. JCO Clinical Cancer Informatics 2019, 3: 1-11. PMID: 30807208, PMCID: PMC6446086, DOI: 10.1200/cci.18.00133.Peer-Reviewed Original ResearchConceptsConvolutional neural networkNeural networkDeep learning modelsImage convolutionLearning modelModel performanceBackground parenchymal uptakeTesting dataComputer algorithmAlgorithmExpert radiologistsNetworkDirect matchingDirect matchAccuracyImagesClassificationResearch purposesPerformanceBreast imagingConvolutionEncodingMatchingModelingTrainingMolecular breast imaging detected invasive lobular carcinoma in dense breasts: A case report
Samreen N, Hunt KN, Hruska CB, Rhodes DJ. Molecular breast imaging detected invasive lobular carcinoma in dense breasts: A case report. Clinical Case Reports 2019, 7: 442-444. PMID: 30899468, PMCID: PMC6406216, DOI: 10.1002/ccr3.1945.Peer-Reviewed Original Research
2018
NCCN Guidelines Insights: Small Cell Lung Cancer, Version 2.2018.
Kalemkerian GP, Loo BW, Akerley W, Attia A, Bassetti M, Boumber Y, Decker R, Dobelbower MC, Dowlati A, Downey RJ, Florsheim C, Ganti AKP, Grecula JC, Gubens MA, Hann CL, Hayman JA, Heist RS, Koczywas M, Merritt RE, Mohindra N, Molina J, Moran CA, Morgensztern D, Pokharel S, Portnoy DC, Rhodes D, Rusthoven C, Sands J, Santana-Davila R, Williams CC, Hoffmann KG, Hughes M. NCCN Guidelines Insights: Small Cell Lung Cancer, Version 2.2018. Journal Of The National Comprehensive Cancer Network : JNCCN 2018, 16: 1171-1182. PMID: 30323087, DOI: 10.6004/jnccn.2018.0079.Peer-Reviewed Original ResearchQuantitative background parenchymal uptake on molecular breast imaging and breast cancer risk: a case-control study
Hruska CB, Geske JR, Swanson TN, Mammel AN, Lake DS, Manduca A, Conners AL, Whaley DH, Scott CG, Carter RE, Rhodes DJ, O’Connor M, Vachon CM. Quantitative background parenchymal uptake on molecular breast imaging and breast cancer risk: a case-control study. Breast Cancer Research 2018, 20: 46. PMID: 29871661, PMCID: PMC5989426, DOI: 10.1186/s13058-018-0973-3.Peer-Reviewed Original ResearchBest Practices in Molecular Breast Imaging: A Guide for Technologists
Swanson T, Tran TD, Ellingson L, O’Connor M, Rhodes DJ, Hunt KN, Conners A, Hruska CB. Best Practices in Molecular Breast Imaging: A Guide for Technologists. Journal Of Nuclear Medicine Technology 2018, 46: 3-11. PMID: 29438007, DOI: 10.2967/jnmt.117.204263.Peer-Reviewed Original Research
2017
Long-term outcomes and predictors of failure after surgery for stage IV apical pelvic organ prolapse
Linder BJ, El-Nashar SA, Mukwege AA, Weaver AL, McGree ME, Rhodes DJ, Gebhart JB, Klingele CJ, Occhino JA, Trabuco EC. Long-term outcomes and predictors of failure after surgery for stage IV apical pelvic organ prolapse. International Urogynecology Journal 2017, 29: 803-810. PMID: 28921036, DOI: 10.1007/s00192-017-3482-5.Peer-Reviewed Original ResearchConceptsUterosacral ligament suspensionApical pelvic organ prolapsePelvic organ prolapseProlapse recurrencePrior hysterectomyProlapse symptomsOrgan prolapseCox proportional hazards modelRecurrent prolapse symptomsMethodsThe medical recordsKaplan-Meier methodType of surgeryLong-term outcomesPredictors of failureApical prolapse repairProportional hazards modelConclusionsYounger agePrimary outcomeSurgical retreatmentApical prolapseProlapse repairExcellent survivalMedical recordsSurgical techniqueSurvival timePatient Acceptance of Half-dose Vs. Half-time Molecular Breast Imaging
Swanson TN, Tran TD, Hruska CB, Solberg CM, Rhodes DJ, Hunt KN, Conners AL, O'Connor MK. Patient Acceptance of Half-dose Vs. Half-time Molecular Breast Imaging. Journal Of Medical Imaging And Radiation Sciences 2017, 49: 39-43. PMID: 30479286, DOI: 10.1016/j.jmir.2017.08.003.Peer-Reviewed Original ResearchConceptsMolecular breast imagingExact testFisher's exact testDuration of examinationBreast imagingPatients' opinionsPatient acceptanceDose reductionExamination comfortMost womenPatient comfortFemale volunteersRadiation doseExamination typesDoseExamination preferencesImagingPatientsGroupNumber of strategiesSurvey responsesVolunteersWomen