2021
Background Parenchymal Uptake on Molecular Breast Imaging and Breast Cancer Risk: A Cohort Study.
Hruska CB, Geske JR, Conners AL, Whaley DH, Rhodes DJ, O'Connor MK, Carter RE, Scott CG, Vachon CM. Background Parenchymal Uptake on Molecular Breast Imaging and Breast Cancer Risk: A Cohort Study. American Journal Of Roentgenology 2021, 216: 1193-1204. PMID: 32755210, PMCID: PMC8640999, DOI: 10.2214/ajr.20.23854.Peer-Reviewed Original ResearchConceptsBackground parenchymal uptakeMolecular breast imagingPostmenopausal womenBreast cancer riskAbsolute riskBreast cancerCohort studyDiscriminatory accuracyDense breastsRisk factorsParenchymal uptakeCancer riskRisk scoreFuture breast cancer diagnosisGreater breast cancer riskBreast cancer risk factorsCox proportional hazards modelGail risk scoreBreast cancer eventsIndependent risk factorSubset of womenCancer risk factorsCase-control studyProportional hazards modelBreast cancer diagnosisComparison of Universal Genetic Testing vs Guideline-Directed Targeted Testing for Patients With Hereditary Cancer Syndrome
Samadder N, Riegert-Johnson D, Boardman L, Rhodes D, Wick M, Okuno S, Kunze K, Golafshar M, Uson P, Mountjoy L, Ertz-Archambault N, Patel N, Rodriguez E, Lizaola-Mayo B, Lehrer M, Thorpe C, Yu N, Esplin E, Nussbaum R, Sharp R, Azevedo C, Klint M, Hager M, Macklin-Mantia S, Bryce A, Bekaii-Saab T, Sekulic A, Stewart A. Comparison of Universal Genetic Testing vs Guideline-Directed Targeted Testing for Patients With Hereditary Cancer Syndrome. JAMA Oncology 2021, 7: 230-237. PMID: 33126242, PMCID: PMC7600058, DOI: 10.1001/jamaoncol.2020.6252.Peer-Reviewed Original ResearchConceptsPrevalence of pathogenic germline variantsFamily variant testingPathogenic germline variantsSolid tumor cancersHigh-penetrance cancer susceptibility genesFamily history of cancerMayo Clinic Cancer CenterRisk-reducing interventionsUniversal genetic testingMultigene panel testingHigh-penetrance variantsHistory of cancerClinic Cancer CenterUniversal testing approachGermline variantsGuideline-directed approachYounger age of diagnosisTumor cancersCancer susceptibility genesClinically actionable findingsTargeted testingCancer screeningAge of diagnosisGermline testingVariant testing
2015
Effect of Menstrual Cycle Phase on Background Parenchymal Uptake at Molecular Breast Imaging
Hruska CB, Conners AL, Vachon CM, O'Connor MK, Shuster LT, Bartley AC, Rhodes DJ. Effect of Menstrual Cycle Phase on Background Parenchymal Uptake at Molecular Breast Imaging. Academic Radiology 2015, 22: 1147-1156. PMID: 26112057, PMCID: PMC4532620, DOI: 10.1016/j.acra.2015.04.003.Peer-Reviewed Original ResearchMeSH KeywordsAdultBreastBreast DensityChromatography, LiquidCohort StudiesEstradiolEstroneFemaleFollicle Stimulating HormoneFollicular PhaseHumansLuteal PhaseMammographyMiddle AgedMolecular ImagingPremenopauseProgesteroneProspective StudiesRadiopharmaceuticalsSex Hormone-Binding GlobulinTandem Mass SpectrometryTechnetium Tc 99m SestamibiTestosteroneConceptsBackground parenchymal uptakeMolecular breast imagingMenstrual cycle phaseLuteal phaseMenstrual cycleNondense breastsFollicular phaseHormone levelsParenchymal uptakeDense breastsExogenous hormone useRegular menstrual cyclesLevels of TCCycle phaseNormal fibroglandular tissuePremenopausal volunteersPremenopausal womenHormone useSpearman correlation coefficientBreast imagingStudy radiologistsMammographic densityBreastFibroglandular tissueWomen
2011
Adherence to Preventive Recommendations: Experience of a Cohort Presenting for Executive Health Care
Shippee ND, Mullan RJ, Nabhan M, Kermott CA, Hagen PT, Rhodes DJ, Montori VM, Murad MH. Adherence to Preventive Recommendations: Experience of a Cohort Presenting for Executive Health Care. Population Health Management 2011, 15: 65-70. PMID: 22092188, DOI: 10.1089/pop.2011.0029.Peer-Reviewed Original ResearchConceptsCancer screeningPreventive servicesOptimal adherence ratesColorectal cancer screeningCervical cancer screeningHealth careMultivariate logistic regressionPredictors of adherencePneumococcal vaccinationTetanus immunizationAdherence ratesPreventive recommendationsHealth behaviorsQuality improvement processDisease preventionLogistic regressionSocioeconomic statusAdherenceImmunizationUse concernsCareUsual barriersScreeningPatientsPresenting
2009
Increased cardiovascular mortality after early bilateral oophorectomy
Rivera CM, Grossardt BR, Rhodes DJ, Brown RD, Roger VL, Melton LJ, Rocca WA. Increased cardiovascular mortality after early bilateral oophorectomy. Menopause The Journal Of The North American Menopause Society 2009, 16: 15-23. PMID: 19034050, PMCID: PMC2755630, DOI: 10.1097/gme.0b013e31818888f7.Peer-Reviewed Original ResearchConceptsAge 45 yearsBilateral oophorectomyReferent womenCardiovascular diseaseUnilateral oophorectomyCardiovascular mortalityEstrogen treatmentEarly bilateral oophorectomyOnset of menopauseOophorectomy cohortCardiac mortalityOlmsted CountyCohort studyCerebrovascular causesOophorectomyAge strataMortalityDiseaseWomenMenopauseEstrogenTreatmentSame populationYearsCohort