Premature menopause or early menopause: Long-term health consequences
Shuster LT, Rhodes DJ, Gostout BS, Grossardt BR, Rocca WA. Premature menopause or early menopause: Long-term health consequences. Maturitas 2009, 65: 161-166. PMID: 19733988, PMCID: PMC2815011, DOI: 10.1016/j.maturitas.2009.08.003.Peer-Reviewed Original ResearchConceptsPremature menopauseEarly menopauseAdverse outcomesEstrogen treatmentHealth consequencesLong-term health consequencesMayo Clinic Cohort StudyOnset of menopauseTime of menopauseCohort studyMedian ageOverall mortalityEstrogen deficiencyNatural menopauseCardiovascular diseaseLong-term consequencesCurrent evidenceMenopausePsychiatric diseasesNeurological diseasesHormonal mechanismsDiseaseWomenOutcomesEarly ageIncreased cardiovascular mortality after early bilateral oophorectomy
Rivera CM, Grossardt BR, Rhodes DJ, Brown RD, Roger VL, Melton LJ, Rocca WA. Increased cardiovascular mortality after early bilateral oophorectomy. Menopause The Journal Of The North American Menopause Society 2009, 16: 15-23. PMID: 19034050, PMCID: PMC2755630, DOI: 10.1097/gme.0b013e31818888f7.Peer-Reviewed Original ResearchConceptsAge 45 yearsBilateral oophorectomyReferent womenCardiovascular diseaseUnilateral oophorectomyCardiovascular mortalityEstrogen treatmentEarly bilateral oophorectomyOnset of menopauseOophorectomy cohortCardiac mortalityOlmsted CountyCohort studyCerebrovascular causesOophorectomyAge strataMortalityDiseaseWomenMenopauseEstrogenTreatmentSame populationYearsCohort