2019
Molecular Breast Imaging in Patients with Suspicious Calcifications
Hunt K, Hruska C, Johnson M, Conners A, O’connor M, Rhodes D, Basappa S, Wahner-Roedler D. Molecular Breast Imaging in Patients with Suspicious Calcifications. Journal Of Breast Imaging 2019, 1: 303-309. PMID: 38424809, DOI: 10.1093/jbi/wbz054.Peer-Reviewed Original ResearchMolecular breast imagingSuspicious calcificationsNegative predictive valueTelluride gamma cameraPredictive valueMedian pathologic sizeInvasive ductal cancerOccult breast cancerInjection of TcAreas of calcificationBreast imagingNuclear medicine techniquesPrebiopsy settingGamma cameraBiopsy findingsDuctal cancerPathologic sizeIncidental lesionsDuctal carcinomaInvasive cancerAdditional biopsiesBreast cancerStereotactic biopsyBiopsyMolecular breast
2015
Diagnostic workup and costs of a single supplemental molecular breast imaging screen of mammographically dense breasts.
Hruska CB, Conners AL, Jones KN, O'Connor MK, Moriarty JP, Boughey JC, Rhodes DJ. Diagnostic workup and costs of a single supplemental molecular breast imaging screen of mammographically dense breasts. American Journal Of Roentgenology 2015, 204: 1345-53. PMID: 26001247, PMCID: PMC5036572, DOI: 10.2214/ajr.14.13306.Peer-Reviewed Original ResearchConceptsBenign biopsy rateDiagnostic workupBiopsy rateDense breastsAdditional diagnostic workupCancer detection rateMammography of womenBreast imaging examinationsPositive predictive valueDual-head gamma cameraImaging examinationsPredictive valueMolecular breastBiopsyPatientsWorkupBreastScreening mammographyCancerWomenMammographyMalignancyReference standardGamma cameraDetection rate
2012
Proof of concept for low‐dose molecular breast imaging with a dual‐head CZT gamma camera. Part II. Evaluation in patients
Hruska CB, Weinmann AL, Skjerseth C, Wagenaar EM, Conners AL, Tortorelli CL, Maxwell RW, Rhodes DJ, O'Connor MK. Proof of concept for low‐dose molecular breast imaging with a dual‐head CZT gamma camera. Part II. Evaluation in patients. Medical Physics 2012, 39: 3476-3483. PMID: 22755727, PMCID: PMC3376157, DOI: 10.1118/1.4719959.Peer-Reviewed Original ResearchConceptsMolecular breast imagingMBq TcDiagnostic accuracyIntrareader agreementMedian lesion sizeLesion detectionPatient studiesEffective radiation doseTelluride gamma cameraSimilar diagnostic accuracyAdequate lesion detectionAdjunct screening techniqueGamma cameraAdministered dosesCount densityClinical careSeparate cohortLesion sizeMBq injectionMolecular breastLow dosesPatientsDense breastsBreast lesionsDoses
2008
Molecular breast imaging: use of a dual-head dedicated gamma camera to detect small breast tumors.
Hruska CB, Phillips SW, Whaley DH, Rhodes DJ, O'Connor MK. Molecular breast imaging: use of a dual-head dedicated gamma camera to detect small breast tumors. American Journal Of Roentgenology 2008, 191: 1805-15. PMID: 19020253, PMCID: PMC3885170, DOI: 10.2214/ajr.07.3693.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedAged, 80 and overBreast NeoplasmsEquipment DesignEquipment Failure AnalysisFemaleGamma CamerasHumansImage EnhancementMiddle AgedMolecular Probe TechniquesRadionuclide ImagingRadiopharmaceuticalsReproducibility of ResultsSensitivity and SpecificitySingle-Blind MethodTechnetium Tc 99m SestamibiConceptsMolecular breast imagingMolecular breastBI-RADS category 4Breast imagingMBq of technetiumSmall breast tumorsTelluride gamma cameraGamma cameraSubcentimeter lesionsUptake scoreAdditional cancersBlinded reviewDetection of cancerBreast tumorsLesionsSmall lesionsBreastPatientsBreast lesionsBlinded readersCancerOblique viewCategory 4Mediolateral oblique viewTumors
2007
Molecular breast imaging: advances and limitations of a scintimammographic technique in patients with small breast tumors
O'Connor M, Phillips S, Hruska C, Rhodes D, Collins D. Molecular breast imaging: advances and limitations of a scintimammographic technique in patients with small breast tumors. Clinical Imaging 2007, 31: 295. DOI: 10.1016/j.clinimag.2007.04.010.Peer-Reviewed Original ResearchMolecular breast imagingSmall breast tumorsBreast tumorsEvidence of cancerFalse-positive scansLarger patient populationMalignant breast tumorsStandard mammographic viewsMBq technetiumOccult tumorsPatient populationMalignant tumorsPatientsTumorsBreast tissueSubjective discomfortBiopsySurgeryMammographic viewsGamma cameraBreast imagingBreast thicknessPreliminary studyRegular detectionView gamma cameraMolecular Breast Imaging: Advantages and Limitations of a Scintimammographic Technique in Patients with Small Breast Tumors
O'Connor MK, Phillips SW, Hruska CB, Rhodes DJ, Collins DA. Molecular Breast Imaging: Advantages and Limitations of a Scintimammographic Technique in Patients with Small Breast Tumors. The Breast Journal 2007, 13: 3-11. PMID: 17214787, DOI: 10.1111/j.1524-4741.2006.00356.x.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultAgedAged, 80 and overBreast NeoplasmsCarcinoma, Ductal, BreastCarcinoma, Intraductal, NoninfiltratingCarcinoma, LobularCarcinoma, PapillaryFemaleHumansMammographyMiddle AgedPredictive Value of TestsRadionuclide ImagingSensitivity and SpecificityTechnetium Tc 99m SestamibiUltrasonographyConceptsMolecular breast imagingSmall breast tumorsBreast tumorsEvidence of cancerFalse-positive scansLarger patient populationMalignant breast tumorsStandard mammographic viewsMBq TcOccult tumorsPatient populationMalignant tumorsPositive scansPatientsTumorsBreast tissueSubjective discomfortBiopsySurgeryMammographic viewsGamma cameraBreast imagingBreast thicknessPreliminary studyRegular detection
2005
Molecular Breast Imaging: A New Technique Using Technetium Tc 99m Scintimammography to Detect Small Tumors of the Breast
Rhodes DJ, O'Connor MK, Phillips SW, Smith RL, Collins DA. Molecular Breast Imaging: A New Technique Using Technetium Tc 99m Scintimammography to Detect Small Tumors of the Breast. Mayo Clinic Proceedings 2005, 80: 24-30. DOI: 10.4065/80.1.24.Peer-Reviewed Original ResearchConceptsMolecular breast imagingMalignant lesionsTechnetium TcBreast parenchymaEvidence of cancerTrue-negative scansFalse-positive scansSensitivity of mammographyTelluride gamma cameraMagnetic resonance imagingTrue positive casesMalignant breast lesionsGamma cameraFat necrosisFalse-positive resultsSmall cancersAdditional lesionsDetection of lesionsSmall tumorsPatientsBenign fibroadenomasLesionsResonance imagingBreast contralateralSurgery