2011
Acute destruction of the synaptic ribbon reveals a role for the ribbon in vesicle priming
Snellman J, Mehta B, Babai N, Bartoletti TM, Akmentin W, Francis A, Matthews G, Thoreson W, Zenisek D. Acute destruction of the synaptic ribbon reveals a role for the ribbon in vesicle priming. Nature Neuroscience 2011, 14: 1135-1141. PMID: 21785435, PMCID: PMC3171202, DOI: 10.1038/nn.2870.Peer-Reviewed Original ResearchMeSH KeywordsAlcohol OxidoreductasesAnimalsBiophysicsCo-Repressor ProteinsDNA-Binding ProteinsElectric StimulationExcitatory Postsynaptic PotentialsExocytosisIn Vitro TechniquesLightMiceMice, Inbred C57BLMicroscopy, Electron, TransmissionPatch-Clamp TechniquesPeptidesPhosphoproteinsProtein BindingRetinaRetinal Bipolar CellsSynapsesSynaptic VesiclesTime FactorsUrodela
2010
Real-time visualization of complexin during single exocytic events
An SJ, Grabner CP, Zenisek D. Real-time visualization of complexin during single exocytic events. Nature Neuroscience 2010, 13: 577-583. PMID: 20383135, PMCID: PMC2860691, DOI: 10.1038/nn.2532.Peer-Reviewed Original ResearchMeSH KeywordsAdaptor Proteins, Vesicular TransportAnimalsDopamineExocytosisGene Expression RegulationGreen Fluorescent ProteinsHumansMicroscopy, ConfocalNerve Tissue ProteinsNeuropeptide YPC12 CellsPhotobleachingProtein BindingPyridinium CompoundsQuaternary Ammonium CompoundsRatsRNA InterferenceSNARE ProteinsTissue Plasminogen ActivatorTransfection
2009
Imaging Exocytosis in Retinal Bipolar Cells with TIRF Microscopy
Joselevitch C, Zenisek D. Imaging Exocytosis in Retinal Bipolar Cells with TIRF Microscopy. Journal Of Visualized Experiments 2009, 1305. PMID: 19513018, PMCID: PMC2794884, DOI: 10.3791/1305.Peer-Reviewed Original ResearchConceptsRetinal bipolar cellsBipolar cellsSynaptic vesiclesTotal internal reflectance fluorescence microscopyLarge axon terminalsBipolar cell terminalsPatch pipette solutionTIRF microscopyImaging ExocytosisGlutamatergic vesiclesAxon terminalsGoldfish retinaSynaptic releaseSynaptic terminalsPipette solutionCell membraneCell terminalsFluorescence microscopyVesiclesRinger's solutionExocytosisCellsIndex substanceActive zoneEndocytosis
2005
Recent progress towards understanding the synaptic ribbon
Prescott ED, Zenisek D. Recent progress towards understanding the synaptic ribbon. Current Opinion In Neurobiology 2005, 15: 431-436. PMID: 16023852, DOI: 10.1016/j.conb.2005.07.005.Peer-Reviewed Original Research