1998
Diversification of Subtype E Human Immunodeficiency Virus Type 1 env in Heterosexual Seroconverters from Northern Thailand
Wang Z, Lyles C, Beyrer C, Celentano D, Vlahov D, Natpratan C, Markham R, Khamboonruang C, Nelson K, Yu X. Diversification of Subtype E Human Immunodeficiency Virus Type 1 env in Heterosexual Seroconverters from Northern Thailand. The Journal Of Infectious Diseases 1998, 178: 1507-1511. PMID: 9780276, DOI: 10.1086/314441.Peer-Reviewed Original ResearchConceptsHIV-1 infectionAsymptomatic HIV-1-infected subjectsHIV-1 subtype EHIV-1-infected subjectsHuman Immunodeficiency Virus Type 1 EnvSubtype E HIVC2-V3 regionHuman immunodeficiency virusHIV vaccine developmentInjection drug usersE HIVRecent seroconvertersImmunodeficiency virusSubtype ESeroconvertersHIV-1Drug usersVaccine developmentMolecular epidemiologyEnv sequencesInfectionEnvNorthern ThailandHIVBaltimoreInfection with Dual-Tropic Human Immunodeficiency Virus Type 1 Variants Associated with Rapid Total T Cell Decline and Disease Progression in Injection Drug Users
Yu X, Wang Z, Vlahov D, Markham R, Farzadegan H, Margolick J. Infection with Dual-Tropic Human Immunodeficiency Virus Type 1 Variants Associated with Rapid Total T Cell Decline and Disease Progression in Injection Drug Users. The Journal Of Infectious Diseases 1998, 178: 388-396. PMID: 9697718, DOI: 10.1086/515646.Peer-Reviewed Original ResearchMeSH KeywordsAdultAmino Acid SequenceCD4 Lymphocyte CountCD4-Positive T-LymphocytesCD8-Positive T-LymphocytesCell LineCells, CulturedDisease ProgressionFemaleGenetic VariationHIV Envelope Protein gp120HIV SeropositivityHIV-1HumansMaleMolecular Sequence DataPeptide FragmentsSequence Homology, Amino AcidSubstance Abuse, IntravenousT-LymphocytesTime FactorsConceptsInjection drug usersSI variantsDisease progressionHuman immunodeficiency virus type 1 variantsDrug usersHuman immunodeficiency virus type 1Immunodeficiency virus type 1HIV-1 transmissionT cell levelsSlow disease progressionT-cell declineDual-tropic virusesType 1 variantsSyncytium-inducing (SI) variantsVirus type 1T cell linesDual tropicNSI variantsSlow progressorsRapid progressionNSI phenotypeT cellsCell declineInitial infectionType 1
1996
Evidence for HIV Type 1 Strains of U.S. Intravenous Drug Users as Founders of AIDS Epidemic among Intravenous Drug Users in Northern Europe
Lukashov V, Kuiken C, Vlahov D, Coutinho R, Goudsmit J. Evidence for HIV Type 1 Strains of U.S. Intravenous Drug Users as Founders of AIDS Epidemic among Intravenous Drug Users in Northern Europe. AIDS Research And Human Retroviruses 1996, 12: 1179-1183. PMID: 8844022, DOI: 10.1089/aid.1996.12.1179.Peer-Reviewed Original ResearchMeSH KeywordsAcquired Immunodeficiency SyndromeEuropeHIV Envelope Protein gp120HIV-1HumansMaleMolecular Sequence DataSequence AnalysisSubstance Abuse, IntravenousUnited StatesConceptsIntravenous drug usersHomosexual menDrug usersV3 sequencesEuropean intravenous drug usersHIV Type 1 StrainsAIDS epidemicHIV-1 epidemicGp120 V3 loopSignature pattern analysisType 1 strainsRisk groupsV3 loopEpidemiological linkMenEpidemicVirusUnited StatesSuggestive evidencePresent suggestive evidenceHigh levelsNucleotide substitutionsEuropean origin