1996
Effect of Mycobacterium tuberculosis on HIV replication. Role of immune activation.
Goletti D, Weissman D, Jackson R, Graham N, Vlahov D, Klein R, Munsiff S, Ortona L, Cauda R, Fauci A. Effect of Mycobacterium tuberculosis on HIV replication. Role of immune activation. The Journal Of Immunology 1996, 157: 1271-8. PMID: 8757635, DOI: 10.4049/jimmunol.157.3.1271.Peer-Reviewed Original ResearchConceptsHIV replicationMTB diseaseMycobacterium tuberculosisLymph node mononuclear cellsViral replicationCellular activationProtein derivative positivityPlasma viral loadAg-specific activationT cell-depleted lymphocytesPPD-negative donorsHIV diseaseHIV infectionAcute phaseViral loadImmune activationMononuclear cellsPPD positivityHealthy donorsHIV epidemicT cellsPrimary PBMCsHIV infection modelEpidemiology dataHIV
1995
Identification of Human Immunodeficiency Virus Primary Isolates Resistant to Interferon-α and Correlation of Prevalence to Disease Progression
Kiinzi M, Farzadegan H, Margolick J, Vlahov D, Pitha P. Identification of Human Immunodeficiency Virus Primary Isolates Resistant to Interferon-α and Correlation of Prevalence to Disease Progression. The Journal Of Infectious Diseases 1995, 171: 822-828. PMID: 7706808, DOI: 10.1093/infdis/171.4.822.Peer-Reviewed Original ResearchConceptsCD4 cell numbersHIV infectionIFN-alphaLow CD4 cell numbersSerum IFN-alpha levelsHuman immunodeficiency virusIFN-alpha levelsEndogenous IFN-alphaAbsence of AIDSCourse of infectionCell numberCorrelation of prevalenceIFN-alpha 2Immunodeficiency virusDisease progressionPrimary isolatesCell tropismResistant variantsAlpha 2InfectionAIDSPrevalenceFavor survivalSequential analysisIsolates