2001
Initial Plasma HIV-1 RNA Levels and Progression to AIDS in Women and Men
Sterling T, Vlahov D, Astemborski J, Hoover D, Margolick J, Quinn T. Initial Plasma HIV-1 RNA Levels and Progression to AIDS in Women and Men. New England Journal Of Medicine 2001, 344: 720-725. PMID: 11236775, DOI: 10.1056/nejm200103083441003.Peer-Reviewed Original ResearchMeSH KeywordsAcquired Immunodeficiency SyndromeAdultAnti-HIV AgentsCD4 Lymphocyte CountDisease ProgressionDisease-Free SurvivalEligibility DeterminationFemaleHIV AntibodiesHIV InfectionsHIV-1HumansLongitudinal StudiesMalePractice Guidelines as TopicRegression AnalysisReverse Transcriptase Polymerase Chain ReactionRiskRNA, ViralSex FactorsViral LoadConceptsInitial viral loadMedian initial viral loadHIV-1 RNAViral loadLymphocyte countHuman immunodeficiency virus type 1 (HIV-1) infectionPlasma HIV-1 RNA levelsHIV-1 RNA levelsHIV-1 RNA copiesFemale injection drug usersVirus type 1 infectionHIV-1 seroconversionMedian initial CD4Risk of progressionHIV-1 infectionType 1 infectionInjection drug usersLikelihood of progressionRate of progressionAntiretroviral therapyInitial CD4Hazard ratioAntiretroviral treatmentTreatment guidelinesImmunodeficiency syndrome
1995
Changes in Markers of Disease Progression in HIV-1 Seroconverters
Galai N, Vlahov D, Margolick J, Chen K, Graham N, Munoz A. Changes in Markers of Disease Progression in HIV-1 Seroconverters. JAIDS Journal Of Acquired Immune Deficiency Syndromes 1995, 8: 66-82. PMID: 8548349, DOI: 10.1097/00042560-199501000-00011.Peer-Reviewed Original ResearchConceptsHomosexual menDrug usersDisease progressionRisk groupsHuman immunodeficiency virus (HIV) disease progressionHIV-1 seroconversionHIV-1 seroconvertersT lymphocyte subsetsImmune deficiency syndromeWhite homosexual menCD8 percentagesTotal lymphocytesHIV infectionSimilar CD4HIV seroconvertersDeficiency syndromeInitial courseSeroconversionCD4Long incubation periodSeroconvertersMenCohortInfectionSimilar rates