2023
Risk factors for suicide among veterans living with and without HIV: a nested case-control study
Smith A, Goulet J, Vlahov D, Justice A, Womack J. Risk factors for suicide among veterans living with and without HIV: a nested case-control study. AIDS And Behavior 2023, 28: 115-124. PMID: 37751112, PMCID: PMC11289766, DOI: 10.1007/s10461-023-04164-3.Peer-Reviewed Original ResearchHIV-specific risk factorsVeterans Aging Cohort StudyCase-control studyRisk factorsRisk of suicideAging Cohort StudyDiagnosis of HIVMost risk factorsUse of benzodiazepinesConditional logistic regressionMental health treatmentSubstance use disordersPrevious suicide attemptsCohort studyHIV statusRates of suicideHigh prevalenceGeneral populationUse disordersHealth treatmentAffective disordersHIVSuicide attemptsLogistic regressionPWH
2013
Opioid Receptor Polymorphism A118G Associated with Clinical Severity in a Drug Overdose Population
Manini A, Jacobs M, Vlahov D, Hurd Y. Opioid Receptor Polymorphism A118G Associated with Clinical Severity in a Drug Overdose Population. Journal Of Medical Toxicology 2013, 9: 148-154. PMID: 23318993, PMCID: PMC3648633, DOI: 10.1007/s13181-012-0286-3.Peer-Reviewed Original ResearchMeSH KeywordsAdultAlternative SplicingAmino Acid SubstitutionBenzodiazepinesCohort StudiesDrug OverdoseFemaleFollow-Up StudiesGenetic Association StudiesGenetic Predisposition to DiseaseHeart ArrestHumansMaleNarcoticsPilot ProjectsPolymorphism, Single NucleotideProspective StudiesReceptors, Opioid, muRespiratory InsufficiencySeverity of Illness IndexSympathomimeticsUnited StatesConceptsAcute drug overdoseG variant alleleClinical severityVariant allelesEmergency departmentDrug overdoseSingle nucleotide polymorphismsConsecutive adult ED patientsHuman mu-opioid receptor geneReceptor single nucleotide polymorphismsWorse clinical severityAdult ED patientsObservational cohort studyUrban teaching hospitalMu-opioid receptor geneAbove single nucleotide polymorphismsCohort studyED patientsRespiratory arrestCardiac arrestClinical variablesAcute drugSevere outcomesTeaching hospitalBlood samples
2005
Haplotype analysis of the SDF-1 (CXCL12) gene in a longitudinal HIV-1/AIDS cohort study
Modi W, Scott K, Goedert J, Vlahov D, Buchbinder S, Detels R, Donfield S, O'Brien S, Winkler C. Haplotype analysis of the SDF-1 (CXCL12) gene in a longitudinal HIV-1/AIDS cohort study. Genes & Immunity 2005, 6: 691-698. PMID: 16177829, DOI: 10.1038/sj.gene.6364258.Peer-Reviewed Original ResearchMeSH KeywordsAcquired Immunodeficiency SyndromeAdolescentAdultAllelesBlack or African AmericanChemokine CXCL12Chemokines, CXCChildCohort StudiesDisease ProgressionFemaleGene FrequencyHaplotypesHIV InfectionsHIV-1HumansLongitudinal StudiesMaleOdds RatioPolymorphism, Single NucleotideRisk FactorsSurvival AnalysisUnited StatesWhite PeopleConceptsSDF-1 geneCohort studySingle nucleotide polymorphismsAfrican AmericansOnly natural ligandSingle disease outcomesX4 HIV-1HIV-1 infectionAIDS Cohort StudyRisk of infectionMACS cohortDisease outcomeHIV-1Epidemiological studiesSDF-1Significant associationChemokine genesInfectionRs1801157Natural ligandProgressionHaplotype analysisCommon haplotypeCXCR4Cohort496: Urban Neighborhood Socioeconomic Status and Incidence of Depression in a Population-Based Cohort Study
Galea S, Ahern J, Vlahov D. 496: Urban Neighborhood Socioeconomic Status and Incidence of Depression in a Population-Based Cohort Study. American Journal Of Epidemiology 2005, 161: s124-s124. DOI: 10.1093/aje/161.supplement_1.s124c.Peer-Reviewed Original ResearchThe relationship between non‐injection drug use behaviors on progression to AIDS and death in a cohort of HIV seropositive women in the era of highly active antiretroviral therapy use
Kapadia F, Cook J, Cohen M, Sohler N, Kovacs A, Greenblatt R, Choudhary I, Vlahov D. The relationship between non‐injection drug use behaviors on progression to AIDS and death in a cohort of HIV seropositive women in the era of highly active antiretroviral therapy use. Addiction 2005, 100: 990-1002. PMID: 15955015, PMCID: PMC3128378, DOI: 10.1111/j.1360-0443.2005.01098.x.Peer-Reviewed Original ResearchConceptsNon-injection drug useWomen's Interagency HIV StudyHIV progressionMultivariate analysisActive antiretroviral therapy (HAART) eraActive antiretroviral therapy (HAART) useMultivariate Cox proportional hazardsAntiretroviral therapy eraAntiretroviral therapy useFormer usersHIV-seropositive womenProspective cohort studyCells/Cox proportional hazardsDrug use behaviorsUse of stimulantsCause deathHAART initiationHAART utilizationTherapy eraCause mortalityHAART useSeropositive womenAIDS eventsCohort study
2004
Neighborhood characteristics, trauma, and the risk of post-traumatic stress disorder in New York City
Ahern J, Galea S, Tracy M, Vlahov D. Neighborhood characteristics, trauma, and the risk of post-traumatic stress disorder in New York City. Annals Of Epidemiology 2004, 14: 623. DOI: 10.1016/j.annepidem.2004.07.085.Peer-Reviewed Original ResearchRisk of PTSDPost-traumatic stress disorderStress disorderPopulation cohort studyNeighborhood characteristicsCohort studyNew York CityTraumatic event exposureNew York City residentsNeighborhood of residenceMultivariable modelRecurrent traumaTraumatic event experiencesNeighborhood violenceMental healthYork CityDisordersMultiple studiesIndividual-level factorsEvent exposureIndividual-level characteristicsRiskOngoing stressorsLow incomeSocial supportIncrease in Sexual Risk Behavior Associated with Immunologic Response to Highly Active Antiretroviral Therapy among HIV-Infected Injection Drug Users
Tun W, Gange S, Vlahov D, Strathdee S, Celentano D. Increase in Sexual Risk Behavior Associated with Immunologic Response to Highly Active Antiretroviral Therapy among HIV-Infected Injection Drug Users. Clinical Infectious Diseases 2004, 38: 1167-1174. PMID: 15095224, DOI: 10.1086/383033.Peer-Reviewed Original ResearchConceptsInjection drug usersActive antiretroviral therapyHAART initiationCell countAntiretroviral therapyDrug usersSexual intercourseRisk reduction counselingHuman immunodeficiency virusLarge cohort studyDrug injection behaviorInjection of drugsUnprotected sexual intercourseSemiannual visitsReduction counselingCohort studyHIV infectionHIV serostatusImmunodeficiency virusImmunologic responseNeedle sharingBlood samplesSurvival analysisRisk behaviorsCD4
2003
Variability in the Incidence of Human Immunodeficiency Virus, Hepatitis B Virus, and Hepatitis C Virus Infection among Young Injecting Drug Users in New York City
Des Jarlais D, Diaz T, Perlis T, Vlahov D, Maslow C, Latka M, Rockwell R, Edwards V, Friedman S, Monterroso E, Williams I, Garfein R. Variability in the Incidence of Human Immunodeficiency Virus, Hepatitis B Virus, and Hepatitis C Virus Infection among Young Injecting Drug Users in New York City. American Journal Of Epidemiology 2003, 157: 467-471. PMID: 12615611, DOI: 10.1093/aje/kwf222.Peer-Reviewed Original ResearchConceptsHepatitis B virusHuman immunodeficiency virusHepatitis C virusImmunodeficiency virusB virusDrug usersHepatitis C virus infectionC virus infectionInjecting Drug UsersHigh HIV seroprevalenceHigh rateHBV incidenceHCV incidenceHCV transmissionCohort studyHIV seroprevalenceHIV incidenceHIV transmissionYoung Injecting Drug UsersC virusVirus infectionNew York CityIncidenceVirusYork CitySocial Circumstances of Initiation of Injection Drug Use and Early Shooting Gallery Attendance: Implications for HIV Intervention Among Adolescent and Young Adult Injection Drug Users
Fuller C, Vlahov D, Latkin C, Ompad D, Celentano D, Strathdee S. Social Circumstances of Initiation of Injection Drug Use and Early Shooting Gallery Attendance: Implications for HIV Intervention Among Adolescent and Young Adult Injection Drug Users. JAIDS Journal Of Acquired Immune Deficiency Syndromes 2003, 32: 86. PMID: 12514419, DOI: 10.1097/00126334-200301010-00013.Peer-Reviewed Original ResearchConceptsInjection drug usersNew injection drug usersOlder injection drug usersYoung adult injection drug usersDrug usersHigh-risk injection drug usersStreet-recruited injection drug usersAdult injection drug usersYoung injection drug usersGallery attendanceProspective cohort studyInjection drug useMultiple logistic regressionHigh-risk practicesCohort studyMedian ageHIV incidenceHIV prevalenceInnovative intervention strategiesHIV interventionsDrug useLogistic regressionHIVBaseline dataMost participants
2002
Does Bleach Disinfection of Syringes Protect Against Hepatitis C Infection Among Young Adult Injection Drug Users?
Kapadia F, Vlahov D, Jarlais D, Strathdee S, Ouellet L, Kerndt P, E E, Williams I, Garfein R. Does Bleach Disinfection of Syringes Protect Against Hepatitis C Infection Among Young Adult Injection Drug Users? Epidemiology 2002, 13: 738-741. PMID: 12410020, DOI: 10.1097/00001648-200211000-00023.Peer-Reviewed Original ResearchConceptsInjection drug usersAnti-HCV seroconversionHepatitis C virusDrug usersOdds ratioBleach useYoung adult injection drug usersSeronegative injection drug usersMajor public health problemAdult injection drug usersBleach disinfectionHepatitis C infectionProspective cohort studyCase-control studyConditional logistic regressionPublic health problemCessation of injectionsC infectionHCV infectionCohort studyC virusProtective effectHealth problemsSeroconversionLogistic regressionSex-Specific Differences in Circumstances of Initiation into Injecting-Drug Use Among Young Adult Latinos in Harlem, New York City
Diaz T, Vlahov D, Edwards V, Conover S, Monterroso E. Sex-Specific Differences in Circumstances of Initiation into Injecting-Drug Use Among Young Adult Latinos in Harlem, New York City. AIDS And Behavior 2002, 6: 117-122. DOI: 10.1023/a:1015441030030.Peer-Reviewed Original ResearchInjecting Drug UsersInjecting-drug useCircumstances of initiationSexual partnersDrug useFirst injection episodeInjecting Drug UseRecent risk behaviorsCohort studyHIV infectionYoung adult LatinosMedian numberSex-specific differencesUnprotected sexPrevention programsAdult LatinosRisk behaviorsNew York CityHIVMore womenWomenBaseline dataStandardized faceMenInjection episodesHighly active antiretroviral treatment does not increase sexual risk behaviour among French HIV infected injecting drug users
Bouhnik A, Moatti J, Vlahov D, Gallais H, Dellamonica P, Obadia Y. Highly active antiretroviral treatment does not increase sexual risk behaviour among French HIV infected injecting drug users. Journal Of Epidemiology & Community Health 2002, 56: 349. PMID: 11964431, PMCID: PMC1732133, DOI: 10.1136/jech.56.5.349.Peer-Reviewed Original ResearchConceptsSexual risk behaviorsAntiretroviral treatmentDrug usersRisk behaviorsPrescription of HAARTActive antiretroviral therapyProportion of patientsActive antiretroviral treatmentUnprotected sexual intercourseFrench HIVAntiretroviral therapyClinical improvementCohort studyTreatment-NaiveHIV transmissionAIDS careHAARTHIV riskHigh-risk activitiesHospital departmentsSexual riskHIVSexual intercourseMultivariate modelLongitudinal analysisHigh-risk behaviors associated with transition from illicit non-injection to injection drug use among adolescent and young adult drug users: a case-control study
Fuller C, Vlahov D, Ompad D, Shah N, Arria A, Strathdee S. High-risk behaviors associated with transition from illicit non-injection to injection drug use among adolescent and young adult drug users: a case-control study. Drug And Alcohol Dependence 2002, 66: 189-198. PMID: 11906806, DOI: 10.1016/s0376-8716(01)00200-9.Peer-Reviewed Original ResearchConceptsInjection drug usersInjection drug useAge-matched case-control analysisDrug usersDrug useBlood-borne infectionsAge-matched personsCase-control studyConditional logistic regressionCase-control analysisHigh-risk behaviorsNon-injection heroinCharacteristics of personsHIV seroprevalenceCohort studyInjection useAdult drug usersLogistic regressionPrevention effortsSame calendar timeYoung adult drug usersCalendar timePrior yearAfrican AmericansBaselineRisk factors and cumulative incidence of anaemia among HIV-infected injection drug users
Semba R, Shah N, Vlahov D. Risk factors and cumulative incidence of anaemia among HIV-infected injection drug users. International Journal Of STD & AIDS 2002, 13: 119-123. PMID: 11839167, DOI: 10.1258/0956462021924758.Peer-Reviewed Original ResearchConceptsInjection drug usersCumulative incidenceRisk factorsDrug usersMycobacterium avium complex infectionHigher body mass indexBody mass indexLongitudinal cohort studyZidovudine useCohort studyLymphocyte countOral thrushMass indexComplex infectionFemale genderHigh riskLower riskAnemiaMicrocytic anemiaIncidenceWeight lossCells/Marijuana useRiskCD4
2001
Effects of CCR5-Delta32, CCR2-64I, and SDF-1 3'A alleles on HIV-1 disease progression: An international meta-analysis of individual-patient data.
Ioannidis J, Rosenberg P, Goedert J, Ashton L, Benfield T, Buchbinder S, Coutinho R, Eugen-Olsen J, Gallart T, Katzenstein T, Kostrikis L, Kuipers H, Louie L, Mallal S, Margolick J, Martinez O, Meyer L, Michael N, Operskalski E, Pantaleo G, Rizzardi G, Schuitemaker H, Sheppard H, Stewart G, Theodorou I, Ullum H, Vicenzi E, Vlahov D, Wilkinson D, Workman C, Zagury J, O'Brien T. Effects of CCR5-Delta32, CCR2-64I, and SDF-1 3'A alleles on HIV-1 disease progression: An international meta-analysis of individual-patient data. Annals Of Internal Medicine 2001, 135: 782-95. PMID: 11694103, DOI: 10.7326/0003-4819-135-9-200111060-00008.Peer-Reviewed Original ResearchConceptsHIV-1 infectionCCR2-64I alleleHIV-1 RNA levelsHIV-1 disease progressionDevelopment of AIDSIndividual patient dataCCR5-Delta32Decreased riskDisease progressionProtective effectLower HIV-1 RNA levelsRNA levelsProspective cohort studyCase-control studyClear protective effectStrong protective effectChemokine receptor genesRandom-effects modelCCR2-64ICohort studyStudy entryCertain chemokinesAIDSInfectionProgressionTime to initiating highly active antiretroviral therapy among HIV-infected injection drug users
Celentano D, Galai N, Sethi A, Shah N, Strathdee S, Vlahov D, Gallant J. Time to initiating highly active antiretroviral therapy among HIV-infected injection drug users. AIDS 2001, 15: 1707-1715. PMID: 11546947, DOI: 10.1097/00002030-200109070-00015.Peer-Reviewed Original ResearchConceptsInjection drug usersActive antiretroviral therapyAntiretroviral therapyDrug usersCell countLow health care accessNon-HAART regimensAntiretroviral therapy useDual combination therapyProportional hazards regressionMain outcome measuresMore treatment optionsHealth care accessNon-drug usersHAART regimenLow CD4HAART useHIV careCohort studyStudy clinicTherapy useSelf-reported initiationHazards regressionMethadone treatmentTreatment eligibilitySexual Orientation and HIV Infection Prevalence among Young Latino Injection Drug Users in Harlem
Diaz T, Vlahov D, Greenberg B, Cuevas Y, Garfein R. Sexual Orientation and HIV Infection Prevalence among Young Latino Injection Drug Users in Harlem. Journal Of Women's Health 2001, 10: 371-380. PMID: 11445028, DOI: 10.1089/152460901750269698.Peer-Reviewed Original ResearchConceptsInjection drug usersHIV infection prevalenceHIV infectionUnprotected sexHomosexual menDrug usersOlder injection drug usersHeterosexual menInfection prevalenceHIV infection ratesCohort studyHepatitis BAntibody testingWhole cohortSexual transmissionHigh prevalenceHigh riskOlder menHeterosexual womenLarger sample sizeDrug useInfection rateMultivariate analysisNew York CityYoung womenMortality, CD4 Cell Count Decline, and Depressive Symptoms Among HIV-Seropositive Women: Longitudinal Analysis From the HIV Epidemiology Research Study
Ickovics J, Hamburger M, Vlahov D, Schoenbaum E, Schuman P, Boland R, Moore J, Group F. Mortality, CD4 Cell Count Decline, and Depressive Symptoms Among HIV-Seropositive Women: Longitudinal Analysis From the HIV Epidemiology Research Study. JAMA 2001, 285: 1466-1474. PMID: 11255423, DOI: 10.1001/jama.285.11.1466.Peer-Reviewed Original ResearchConceptsHuman immunodeficiency virusChronic depressive symptomsCD4 cell countHIV-seropositive womenTreatment of depressionDepressive symptomsCell countDisease progressionBaseline CD4 cell countCD4 cell count declineHIV Epidemiologic Research StudyCell count declineCD4 lymphocyte countBaseline viral loadEpidemiologic Studies Depression ScaleHIV disease progressionHIV Epidemiology Research StudyLongitudinal cohort studyEpidemiologic research studiesImpact of depressionAcademic medical centerSelf-reported CenterCohort studyLymphocyte countCount decline
2000
The prevalence of homelessness among injection drug users with and without HIV infection
Song J, Safaeian M, Strathdee S, Vlahov D, Celentano D. The prevalence of homelessness among injection drug users with and without HIV infection. Journal Of Urban Health 2000, 77: 678-687. PMID: 11194310, PMCID: PMC3456762, DOI: 10.1007/bf02344031.Peer-Reviewed Original ResearchConceptsHuman immunodeficiency virusInjection drug usersInjection drug useIndependent predictorsDrug usersDrug useActive injection drug useLongitudinal cohort studyCross-sectional studyHIV/AIDSCross-sectional investigationHIV seroconversionCohort studyHIV seroprevalenceHIV infectionPrevalence of homelessnessImmunodeficiency virusMale sexLogistic regressionPrevalenceParticipantsMore experiencePredictorsSeroconversionSerostatusInfluence of CCR5 promoter haplotypes on AIDS progression in African–Americans
An P, Martin M, Nelson G, Carrington M, Smith M, Gong K, Vlahov D, O'Brien S, Winkler C. Influence of CCR5 promoter haplotypes on AIDS progression in African–Americans. AIDS 2000, 14: 2117-2122. PMID: 11061652, DOI: 10.1097/00002030-200009290-00007.Peer-Reviewed Original ResearchConceptsCCR5 promoter haplotypesAIDS progressionSurvival analysisAfrican AmericansNatural history cohort studyPromoter haplotypesRate of progressionPromoter variantsCohort studyCCR5 alleleRapid progressionCaucasian cohortProgressionCaucasiansComplete linkage disequilibriumCCR2AIDSUnidentified polymorphismsRacial groupsLinkage disequilibriumSeroconvertersCCR5CohortHaplotypes