1999
Cell-associated infectious HIV-1 viral load as a predictor of clinical progression and survival among HIV-1 infected injection drug users and homosexual men
Lyles C, Graham N, Astemborski J, Vlahov D, Margolick J, Saah A, Farzadegan H. Cell-associated infectious HIV-1 viral load as a predictor of clinical progression and survival among HIV-1 infected injection drug users and homosexual men. European Journal Of Epidemiology 1999, 15: 99-108. PMID: 10204638, DOI: 10.1023/a:1007556327269.Peer-Reviewed Original ResearchMeSH KeywordsAcquired Immunodeficiency SyndromeAdultAIDS-Related Opportunistic InfectionsBacterial InfectionsCause of DeathCD4 Lymphocyte CountCohort StudiesConfidence IntervalsDisease ProgressionFemaleFollow-Up StudiesHIV InfectionsHIV-1Homosexuality, MaleHumansImmunocompromised HostLeukocytes, MononuclearMalePredictive Value of TestsProportional Hazards ModelsRisk FactorsSubstance Abuse, IntravenousSurvival AnalysisSurvival RateViral LoadViremiaConceptsHIV-1 viral loadViral loadHomosexual menRisk groupsHIV-1Relative hazardDrug usersPeripheral blood mononuclear cellsMicroculture techniqueBlood mononuclear cellsInjection drug usersHIV-1 progressionInitial CD4Clinical progressionMononuclear cellsNegative culturesPredictive valueSurvival analysisBacterial infectionsTotal participantsAIDSProgressionInfectious unitsCells/Death
1995
Clinical characteristics and prognostic value of acute retroviral syndrome among injecting drug users
Dorrucci M, Rezza G, Vlahov D, Pezzotti P, Sinicco A, Nicolosi A, Lazzarin A, Galai N, Gafà S, Pristerà R. Clinical characteristics and prognostic value of acute retroviral syndrome among injecting drug users. AIDS 1995, 9: 597-604. PMID: 7662199, DOI: 10.1097/00002030-199506000-00011.Peer-Reviewed Original ResearchConceptsAcute retroviral syndromeHIV infectionHIV seroconvertersRelative hazardDrug usersFirst positive HIV testYear of seroconversionPositive HIV testRate of CD4Kaplan-Meier estimatesCumulative AIDS incidenceAsymptomatic seroconvertersHIV seroconversionClinical characteristicsHIV testClinical progressionPrognostic valueProspective studyClinical centersSeroconvertersCell declineSeroconversionCell countSyndromeNatural history
1994
Direct Comparison of the Relationship Between Clinical Outcome and Change in CD4+ Lymphocytes in Human Immunodeficiency Virus—Positive Homosexual Men and Injecting Drug Users
Margolick J, Muñoz A, Vlahov D, Astemborski J, Solomon L, He X, Nelson K, Saah A. Direct Comparison of the Relationship Between Clinical Outcome and Change in CD4+ Lymphocytes in Human Immunodeficiency Virus—Positive Homosexual Men and Injecting Drug Users. JAMA Internal Medicine 1994, 154: 869-875. PMID: 7908795, DOI: 10.1001/archinte.1994.00420080065006.Peer-Reviewed Original ResearchConceptsHuman immunodeficiency virus-positive homosexual menLymphocyte countHomosexual menImmunodeficiency syndromeDrug usersRate of declineStudy entryClinical outcomesHuman immunodeficiency virus (HIV) infectionDevelopment of thrushMore frequent developmentImmunodeficiency virus infectionT cell subsetsInjecting Drug UsersProgression of diseaseRisk group membershipLower absolute numbersLymphocyte numbersClinical progressionClinical symptomsInitial levelDisease progressionVirus infectionStudy groupCD4