1996
A Combined Cytogenetic and Molecular Approach for Diagnosing Delayed Puberty
Hon Fong Louie Mark, Bayleran J, Seifer D, Meyers-Seifer C. A Combined Cytogenetic and Molecular Approach for Diagnosing Delayed Puberty. Clinical Pediatrics 1996, 35: 62-66. PMID: 8775477, DOI: 10.1177/000992289603500202.Peer-Reviewed Original ResearchConceptsLaparoscopic bilateral gonadectomyRisk of neoplasiaPeripheral blood leukocytesCell linesBilateral gonadectomyPolymerase chain reactionIntact short armsBlood leukocytesDelayed pubertyConventional cytogenetic studiesSubpopulation of cellsShort statureY chromosome materialChromosomal analysisChain reactionPubertyPhenotypic femalesCytogenetic studiesPresent reportCombined CytogeneticSitu hybridizationMolecular analysisUnequivocal evidenceCells
1992
Flow cytometric analysis of deoxyribonucleic acid in human granulosa cells as a function of chronological age and ovulation induction regimen
Seifer DB, Honig J, Penzias AS, Lavy G, Nadkarni PM, Jones EE, DeCherney AH, Flynn SD. Flow cytometric analysis of deoxyribonucleic acid in human granulosa cells as a function of chronological age and ovulation induction regimen. The Journal Of Clinical Endocrinology & Metabolism 1992, 75: 636-640. PMID: 1639962, DOI: 10.1210/jcem.75.2.1639962.Peer-Reviewed Original ResearchConceptsHuman menopausal gonadotropinOvulation induction regimenGreater proliferative indexInduction regimenLeuprolide acetateProliferative indexGranulosa cellsGroup IGroup IIGroup IIIAmpules of hMGFunction of ageFlow cytometryDay of hCGProspective cohort studyGroup of patientsHuman granulosa cellsChronological ageMenopausal gonadotropinCohort studyOvulation inductionSerum FSHSignificant independent influenceOutcome measuresWomen's age