Autologous granulosa cell coculture demonstrates zygote suppression of granulosa cell steroidogenesis**Presented in part at the 51st Annual Meeting of the American Society for Reproductive Medicine. Seattle, Washington, October 7 to 12, 1995.††Supported in part by Physician Scientist Award (AG00566 [D.B.S.] and R01HD31894 [A.L.S.]) from the National Institutes of Health, National Institute on Aging, Bethesda, Maryland.
Seifer D, Freeman M, Gardiner A, Hill G, Schneyer A, Vanderhyden B. Autologous granulosa cell coculture demonstrates zygote suppression of granulosa cell steroidogenesis**Presented in part at the 51st Annual Meeting of the American Society for Reproductive Medicine. Seattle, Washington, October 7 to 12, 1995.††Supported in part by Physician Scientist Award (AG00566 [D.B.S.] and R01HD31894 [A.L.S.]) from the National Institutes of Health, National Institute on Aging, Bethesda, Maryland. Fertility And Sterility 1996, 66: 425-429. PMID: 8751742, DOI: 10.1016/s0015-0282(16)58513-6.Peer-Reviewed Original ResearchConceptsLuteinized granulosa cellsGranulosa cellsStandard IVF-ET treatment cycleIVF-ET treatment cyclesTwo-pronuclear embryosGranulosa cell steroidogenesisTwo-pronuclear zygotesNational InstituteVitro Fertilization UnitProduction of E2Steroid hormone productionPituitary desensitizationOvarian stimulationFollicular aspiratesCell steroidogenesisFertilization unitTreatment cyclesHormone productionCell coculturesReproductive medicineP productionAmerican SocietyAcademic research environmentE2Human embryosSerum inhibin levels are lower in ectopic than intrauterine spontaneously conceived pregnancies*†*Presented in part at the 42nd Annual Meeting of the Society for Gynecological Investigation, Chicago, Illinois, March 15 to 18, 1995.†Supported in part by Physician Scientist Award from National Institutes of Health, National Institute on Aging grant AG00566 (D.B.S.) and HD29164 (G.M.L.M., A.L.S.).
Seifer D, Lambert-Messerlian G, Canick J, Frishman G, Schneyer A. Serum inhibin levels are lower in ectopic than intrauterine spontaneously conceived pregnancies*†*Presented in part at the 42nd Annual Meeting of the Society for Gynecological Investigation, Chicago, Illinois, March 15 to 18, 1995.†Supported in part by Physician Scientist Award from National Institutes of Health, National Institute on Aging grant AG00566 (D.B.S.) and HD29164 (G.M.L.M., A.L.S.). Fertility And Sterility 1996, 65: 667-669. PMID: 8774307, DOI: 10.1016/s0015-0282(16)58174-6.Peer-Reviewed Original ResearchConceptsIntrauterine pregnancySerum inhibin concentrationsDimeric inhibinInhibin concentrationsTotal inhibinMaternal serumSerum samplesDimeric inhibin concentrationSingle intrauterine pregnancySerum inhibin levelsCase-control studyAcademic clinical practiceNational InstituteAlpha-inhibin subunitGynecological InvestigationInhibin levelsSonographic evidenceGestational ageInhibin subunitsWeek 8MAIN OUTCOMEClinical practiceInhibinEctopicWomen