2006
Immunocytochemical evidence for the presence and location of the neurotrophin–Trk receptor family in adult human preovulatory ovarian follicles
Seifer DB, Feng B, Shelden RM. Immunocytochemical evidence for the presence and location of the neurotrophin–Trk receptor family in adult human preovulatory ovarian follicles. American Journal Of Obstetrics And Gynecology 2006, 194: 1129-1134. PMID: 16580310, DOI: 10.1016/j.ajog.2005.12.022.Peer-Reviewed Original ResearchConceptsHuman preovulatory folliclesTrk A receptorCumulus granulosa cellsTrk CTrk BPreovulatory folliclesOvarian folliclesGranulosa cellsFertilization/intracytoplasmic sperm injectionUnfertilized oocytesHuman ovarian folliclesA receptorsAbsence of neurotrophinsIntracytoplasmic sperm injectionPreovulatory ovarian folliclesRespective receptor proteinsReceptor proteinNT-4/5NT-3Prospective studyNeurotrophin receptorSperm injectionNeurotrophinsHuman unfertilized oocytesParacrine function
2002
Brain-Derived Neurotrophic Factor: A Novel Human Ovarian Follicular Protein
Seifer DB, Feng B, Shelden RM, Chen S, Dreyfus CF. Brain-Derived Neurotrophic Factor: A Novel Human Ovarian Follicular Protein. The Journal Of Clinical Endocrinology & Metabolism 2002, 87: 655-659. PMID: 11836300, DOI: 10.1210/jcem.87.2.8213.Peer-Reviewed Original ResearchConceptsBrain-derived neurotrophic factorOocyte maturationSecretion of BDNFSource of BDNFNervous systemRelease of BDNFSoluble polypeptide growth factorsHuman ovarian folliclesHuman follicular fluidCumulus granulosa cellsMammalian nervous systemFollicular proteinsBDNF receptorOocyte retrievalBDNF proteinTrk BNeurotrophic factorPolypeptide growth factorsHuman ovaryMural granulosaFollicular fluidMouse oocyte maturationOvarian folliclesGranulosa cellsEndocrine tissues