2022
Magnetic Susceptibility Source Separation Solely from Gradient Echo Data: Histological Validation
Dimov AV, Gillen KM, Nguyen TD, Kang J, Sharma R, Pitt D, Gauthier SA, Wang Y. Magnetic Susceptibility Source Separation Solely from Gradient Echo Data: Histological Validation. Tomography 2022, 8: 1544-1551. PMID: 35736875, PMCID: PMC9228115, DOI: 10.3390/tomography8030127.Peer-Reviewed Original ResearchHumansImage Interpretation, Computer-AssistedIronMagnetic Resonance ImagingMultiple SclerosisWhite Matter
2014
Quantitative susceptibility mapping (QSM) of white matter multiple sclerosis lesions: Interpreting positive susceptibility and the presence of iron
Wisnieff C, Ramanan S, Olesik J, Gauthier S, Wang Y, Pitt D. Quantitative susceptibility mapping (QSM) of white matter multiple sclerosis lesions: Interpreting positive susceptibility and the presence of iron. Magnetic Resonance In Medicine 2014, 74: 564-570. PMID: 25137340, PMCID: PMC4333139, DOI: 10.1002/mrm.25420.Peer-Reviewed Original ResearchMeSH KeywordsAgedBiomarkersFemaleHumansImage EnhancementImage Interpretation, Computer-AssistedIronMagnetic Resonance ImagingMagnetic Resonance SpectroscopyMaleMolecular ImagingMultiple SclerosisReproducibility of ResultsSensitivity and SpecificityWhite MatterConceptsMultiple sclerosisQuantitative susceptibility mappingIron depositionMS brain tissueMicroglia/macrophagesWhite matter multiple sclerosis lesionsPresence of myelinMultiple sclerosis lesionsSubstantial iron depositionChronic inflammationMS lesionsSclerosis lesionsLesionsBrain tissueMyelinMicroglia
2012
Detecting cortical lesions in multiple sclerosis at 7 T using white matter signal attenuation
Bluestein KT, Pitt D, Sammet S, Zachariah CR, Nagaraj U, Knopp MV, Schmalbrock P. Detecting cortical lesions in multiple sclerosis at 7 T using white matter signal attenuation. Magnetic Resonance Imaging 2012, 30: 907-915. PMID: 22578928, PMCID: PMC3402634, DOI: 10.1016/j.mri.2012.03.006.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedAged, 80 and overAlgorithmsCerebral CortexFemaleHumansImage EnhancementImage Interpretation, Computer-AssistedMagnetic Resonance ImagingMaleMiddle AgedMultiple SclerosisNerve Fibers, MyelinatedReproducibility of ResultsSensitivity and SpecificitySubtraction TechniqueYoung Adult
2011
T1 and proton density at 7 T in patients with multiple sclerosis: an initial study
Bluestein KT, Pitt D, Knopp MV, Schmalbrock P. T1 and proton density at 7 T in patients with multiple sclerosis: an initial study. Magnetic Resonance Imaging 2011, 30: 19-25. PMID: 21937183, PMCID: PMC3375320, DOI: 10.1016/j.mri.2011.07.018.Peer-Reviewed Original ResearchMeSH KeywordsAdultAlgorithmsBrainFemaleHumansImage EnhancementImage Interpretation, Computer-AssistedMagnetic Resonance ImagingMaleMiddle AgedMultiple SclerosisNerve Fibers, MyelinatedProtonsReproducibility of ResultsSensitivity and SpecificityConceptsCortical lesionsMultiple sclerosisWhite matterGray matterHealthy control subjectsWhite matter lesionsNormal-appearing tissueMS patientsMagnetic resonance sequencesMatter lesionsControl subjectsCerebrospinal fluidMS researchLesionsPatientsMR imagingUltrahigh-field MR imagingField MR imagingSclerosisProton densityResonance sequencesTissue responseTurbo fieldMagnetic resonanceInitial study