Cost-effectiveness of nonsteroidal anti-inflammatory drugs and opioids in the treatment of knee osteoarthritis in older patients with multiple comorbidities
Katz JN, Smith SR, Collins JE, Solomon DH, Jordan JM, Hunter DJ, Suter LG, Yelin E, Paltiel AD, Losina E. Cost-effectiveness of nonsteroidal anti-inflammatory drugs and opioids in the treatment of knee osteoarthritis in older patients with multiple comorbidities. Osteoarthritis And Cartilage 2015, 24: 409-418. PMID: 26525846, PMCID: PMC4761310, DOI: 10.1016/j.joca.2015.10.006.Peer-Reviewed Original ResearchAgedAged, 80 and overAnalgesics, OpioidAnti-Inflammatory Agents, Non-SteroidalCelecoxibComorbidityCost-Benefit AnalysisDrug CostsDrug Therapy, CombinationFemaleHealth Services ResearchHumansIbuprofenMaleMiddle AgedNaproxenNonprescription DrugsOsteoarthritis, KneePainPain MeasurementProton Pump InhibitorsQuality-Adjusted Life YearsSensitivity and SpecificityTramadolTreatment OutcomeUnited States