2007
The Effect of Antiretroviral Therapy on Secondary Transmission of HIV among Men Who Have Sex with Men
McCormick AW, Walensky RP, Lipsitch M, Losina E, Hsu H, Weinstein MC, Paltiel AD, Freedberg KA, Seage GR. The Effect of Antiretroviral Therapy on Secondary Transmission of HIV among Men Who Have Sex with Men. Clinical Infectious Diseases 2007, 44: 1115-1122. PMID: 17366461, PMCID: PMC2365722, DOI: 10.1086/512816.Peer-Reviewed Original ResearchConceptsAntiretroviral therapyCohort of individualsHuman immunodeficiency virus RNA loadEffect of ARTImpact of ARTFurther HIV transmissionUnprotected insertive anal intercourseHIV RNA levelsVirus RNA loadCohort of menSecondary transmissionYears of infectionInsertive anal intercourseRisk reduction interventionsHIV diseaseHIV infectionUntreated cohortHIV transmissionRNA loadVirologic courseSecondary casesAnal intercourseSecondary infectionHIVEffective HIV
2006
Expanded HIV screening in the United States: effect on clinical outcomes, HIV transmission, and costs.
Paltiel AD, Walensky RP, Schackman BR, Seage GR, Mercincavage LM, Weinstein MC, Freedberg KA. Expanded HIV screening in the United States: effect on clinical outcomes, HIV transmission, and costs. Annals Of Internal Medicine 2006, 145: 797-806. PMID: 17146064, DOI: 10.7326/0003-4819-145-11-200612050-00004.Peer-Reviewed Original ResearchConceptsCost-effectiveness ratioDollars/QALYHIV prevalenceAnnual incidenceHIV infectionRoutine HIVAntiretroviral therapyIncremental cost-effectiveness ratioModerate HIV prevalenceUndetected HIV infectionVoluntary HIV screeningUndiagnosed HIV infectionRapid HIV testingHIV patient careHIV transmission riskOne-time screeningQuality-adjusted survivalLifetime medical costsServices Utilization SurveySecondary transmissionBase-case analysisCost-effectiveness analysisHIV screeningObservational cohortHIV testing