2004
Slow Adaptation in Fast-Spiking Neurons of Visual Cortex
Descalzo V, Nowak L, Brumberg J, McCormick D, Sanchez-Vives M. Slow Adaptation in Fast-Spiking Neurons of Visual Cortex. Journal Of Neurophysiology 2004, 93: 1111-1118. PMID: 15385594, DOI: 10.1152/jn.00658.2004.Peer-Reviewed Original ResearchConceptsFS neuronsSpike frequency adaptationSlower time courseShort-duration action potentialsTime courseNeuron's functional propertiesPostadaptation periodSlow afterhyperpolarizationCortical slicesNeuron dischargeAfferent inputInhibitory interneuronsVisual cortexAction potentialsNeuronsSlow adaptationPrevious studiesAfterhyperpolarizationInterneuronsExcitabilityCortexDischarge
2003
Electrophysiological Classes of Cat Primary Visual Cortical Neurons In Vivo as Revealed by Quantitative Analyses
Nowak L, Azouz R, Sanchez-Vives M, Gray C, McCormick D. Electrophysiological Classes of Cat Primary Visual Cortical Neurons In Vivo as Revealed by Quantitative Analyses. Journal Of Neurophysiology 2003, 89: 1541-1566. PMID: 12626627, DOI: 10.1152/jn.00580.2002.Peer-Reviewed Original ResearchConceptsAction potentialsElectrophysiological classesCortical neuronsIntrinsic burstingPrimary visual cortical neuronsShort-duration action potentialsCortical neuronal functionSpiny stellate cellsRegular spikingSpiny stellate neuronsVisual cortical neuronsFrequency adaptationCat area 17High-frequency burstsSpike frequency adaptationCH neuronsTonic trainsNonpyramidal cellsIB neuronsRS neuronsStellate neuronsPyramidal cellsArea 17FS neuronsStellate cells
2000
Cellular Mechanisms of Long-Lasting Adaptation in Visual Cortical Neurons In Vitro
Sanchez-Vives M, Nowak L, McCormick D. Cellular Mechanisms of Long-Lasting Adaptation in Visual Cortical Neurons In Vitro. Journal Of Neuroscience 2000, 20: 4286-4299. PMID: 10818164, PMCID: PMC6772630, DOI: 10.1523/jneurosci.20-11-04286.2000.Peer-Reviewed Original ResearchConceptsSpike frequency adaptationSlow afterhyperpolarizationCortical neuronsFerret primary visual cortexProlonged dischargeCellular mechanismsVisual cortical neuronsPrimary visual cortexSlow spike frequency adaptationIntracellular recordingsIntracellular injectionRightward shiftAfterhyperpolarizationVisual cortexReversal potentialContrast adaptationNeuronsDischarge frequencyMembrane conductanceVivoVisual systemBlockadeCortexImportant role
1997
Physiological properties of inhibitory interneurons in cat striate cortex.
Azouz R, Gray C, Nowak L, McCormick D. Physiological properties of inhibitory interneurons in cat striate cortex. Cerebral Cortex 1997, 7: 534-545. PMID: 9276178, DOI: 10.1093/cercor/7.6.534.Peer-Reviewed Original ResearchConceptsBrief action potentialsReceptive field propertiesReceptive field typesSpike frequency adaptationSimple receptive fieldsAxonal arborizationIntracellular recordingsInhibitory interneuronsBasket cellsSpontaneous activityStriate cortexLayers IIAction potentialsFiring patternsResponsive cellsVisual stimulationFrequency adaptationDirection preferenceInterneuronsHigh rateReceptive fieldsCortexCatsCellsSpike trains
1995
Electrophysiological and pharmacological properties of interneurons in the cat dorsal lateral geniculate nucleus
Pape H, McCormick D. Electrophysiological and pharmacological properties of interneurons in the cat dorsal lateral geniculate nucleus. Neuroscience 1995, 68: 1105-1125. PMID: 8544986, DOI: 10.1016/0306-4522(95)00205-w.Peer-Reviewed Original ResearchMeSH KeywordsAction PotentialsAnimalsCatsElectric StimulationElectrophysiologyExcitatory Amino Acid AgonistsExcitatory Amino Acid AntagonistsGABA-A Receptor AgonistsGABA-A Receptor AntagonistsGABA-B Receptor AgonistsGABA-B Receptor AntagonistsGamma-Aminobutyric AcidGeniculate BodiesIn Vitro TechniquesInterneuronsPatch-Clamp TechniquesThalamusConceptsDorsal lateral geniculate nucleusCat dorsal lateral geniculate nucleusLateral geniculate nucleusAction potentialsGeniculate nucleusGABAB receptor agonist baclofenGABAA receptor agonist muscimolSpontaneous action potential activityPharmacological propertiesStrong spike frequency adaptationSmall slow depolarizationSubpopulation of interneuronsReceptor agonist baclofenSpontaneous spike activityAction potential dischargeDorsal lateral geniculateReceptor agonist muscimolApplication of serotoninAction potential activityApplication of acetylcholineChloride equilibrium potentialHigh-frequency trainsSpike frequency adaptationUnique electrophysiological characteristicsAgonist baclofen
1994
Developmental changes in electrophysiological properties of LGNd neurons during reorganization of retinogeniculate connections
Ramoa A, McCormick D. Developmental changes in electrophysiological properties of LGNd neurons during reorganization of retinogeniculate connections. Journal Of Neuroscience 1994, 14: 2089-2097. PMID: 8158259, PMCID: PMC6577110, DOI: 10.1523/jneurosci.14-04-02089.1994.Peer-Reviewed Original ResearchConceptsLGNd neuronsImmature neuronsAction potentialsElectrophysiological propertiesLittle spike frequency adaptationDependent action potentialsAction potential activityEarly postnatal lifeWhole-cell recordingsEarly postnatal developmentPatch-clamp techniqueSpike frequency adaptationHigh input resistanceDorsal LGNImmature synapsesCritical developmental periodRetinogeniculate connectionsMembrane potentialPostnatal weekIntracellular injectionPostnatal lifePostnatal developmentNeuronsInput resistanceFrequency adaptation
1993
Neurotransmitter Control of Neocortical Neuronal Activity and Excitability
McCormick D, Wang Z, Huguenard J. Neurotransmitter Control of Neocortical Neuronal Activity and Excitability. Cerebral Cortex 1993, 3: 387-398. PMID: 7903176, DOI: 10.1093/cercor/3.5.387.Peer-Reviewed Original ResearchConceptsActivation of muscarinicMetabotropic receptorsPyramidal cellsLayers II/IIISingle spike activityGlutamate metabotropic receptorsDuration of EPSPsAction potential generationSpike frequency adaptationCurrent IAHPGABAergic neuronsCortical neuronsGABAA receptorsNMDA receptorsH2-histaminergicNeurotransmitter systemsNeurons resultsSerotoninergic receptorsCortical circuitsNeuronal activityNeurotransmitter controlNeuronal circuitsNeocortical neuronal activityAlpha 1Functional activation
1989
Convergence and divergence of neurotransmitter action in human cerebral cortex.
McCormick D, Williamson A. Convergence and divergence of neurotransmitter action in human cerebral cortex. Proceedings Of The National Academy Of Sciences Of The United States Of America 1989, 86: 8098-8102. PMID: 2573061, PMCID: PMC298222, DOI: 10.1073/pnas.86.20.8098.Peer-Reviewed Original ResearchConceptsHuman cerebral cortexPostsynaptic actionsCerebral cortexPutative neurotransmittersMuscarinic receptor agonistApplication of acetylcholineCortical pyramidal cellsGamma-aminobutyric acidDistinct potassium currentsSpecific anatomical connectionsSpike frequency adaptationPostsynaptic receptorsReceptor agonistPyramidal cellsNeurotransmitter systemsM-currentNeuronal firingNeurotransmitter actionPotassium currentCortical activityAnatomical connectionsSerotoninNeurotransmittersNorepinephrineAcetylcholine