2020
Improving the Safety of Major Resection for Hepatobiliary Malignancy: Portal Vein Embolization and Recent Innovations in Liver Regeneration Strategies
Madoff DC, Odisio BC, Schadde E, Gaba RC, Bennink RJ, van Gulik TM, Guiu B. Improving the Safety of Major Resection for Hepatobiliary Malignancy: Portal Vein Embolization and Recent Innovations in Liver Regeneration Strategies. Current Oncology Reports 2020, 22: 59. PMID: 32415401, DOI: 10.1007/s11912-020-00922-x.Peer-Reviewed Original ResearchConceptsPortal vein embolizationFuture liver remnantFLR hypertrophyMajor hepatectomyVein embolizationHepatobiliary malignanciesCT volumetryAppropriate surgical candidatesExtent of resectionPortal vein ligationRadiation lobectomyVenous deprivationMajor resectionPerformance statusSurgical candidatesComplication rateLiver diseaseVein ligationLiver partitionLiver remnantTumor typesPhysiological imagingResectionEmbolizationMalignancy
2011
The Ipsilateral Approach for Right PVE with or Without Segment 4
Madoff D. The Ipsilateral Approach for Right PVE with or Without Segment 4. 2011, 151-158. DOI: 10.1007/978-1-84882-122-4_17.Peer-Reviewed Original ResearchPortal vein embolizationFuture liver remnantIpsilateral approachSmall future liver remnantRight portal vein embolizationContralateral liver hypertrophyMajor liver resectionStandard of careMajor hepatectomyLiver resectionVein embolizationSubsequent resectionLiver remnantLiver hypertrophyPortal systemResectionSegment 4Operator preferenceEmbolizationPatientsHypertrophyHepatectomyLiverCareComplications of Portal Vein Embolization
Kodama Y, Shaw C, Madoff D. Complications of Portal Vein Embolization. 2011, 159-168. DOI: 10.1007/978-1-84882-122-4_18.Peer-Reviewed Original ResearchPortal vein embolizationVein embolizationStrict patient selectionManagement of complicationsMajor hepatectomyAdverse eventsClinical presentationPatient selectionPotential complicationsEmbolization proceduresClinical successComplicationsEmbolizationHepatectomyComplex proceduresAccess approachMorbidityEtiologyMortality
2008
Preoperative Portal Vein Embolization
Madoff D. Preoperative Portal Vein Embolization. 2008, 316-334. DOI: 10.1017/cbo9780511722226.029.Peer-Reviewed Original ResearchPreoperative portal vein embolizationFuture liver remnantPortal vein embolizationSmall remnant liverFunctional liver massVein embolizationLiver failureRemnant liverLiver massExtensive liver surgeryNon-embolized segmentsNormal underlying liverPerioperative liver failureMajor liver resectionExtended hospital stayFatal liver failureChronic liver diseaseMajor technical complicationsMetastatic liver tumorsStandard of careHepatobiliary centersHospital stayMajor hepatectomyPerioperative morbidityCurative hepatectomyIs embolization of segment 4 portal veins before extended right hepatectomy justified?
Kishi Y, Madoff DC, Abdalla EK, Palavecino M, Ribero D, Chun YS, Vauthey JN. Is embolization of segment 4 portal veins before extended right hepatectomy justified? Surgery 2008, 144: 744-751. PMID: 19081016, PMCID: PMC5901738, DOI: 10.1016/j.surg.2008.05.015.Peer-Reviewed Original ResearchConceptsPreoperative portal vein embolizationPortal vein embolizationPortal veinHypertrophy rateVein embolizationRight portal vein embolizationExtended right hepatectomyLiver remnant volumeMajor hepatectomyRight hepatectomyCurative hepatectomySubsequent resectionClinical outcomesRemnant volumeEmbolizationComplicationsPatientsAbsolute increaseHepatectomyUninjured liverSignificant differencesVeinSegment 2Volume gainResection
2007
Systemic Chemotherapy and Two-Stage Hepatectomy for Extensive Bilateral Colorectal Liver Metastases: Perioperative Safety and Survival
Chun YS, Vauthey JN, Ribero D, Donadon M, Mullen JT, Eng C, Madoff DC, Chang DZ, Ho L, Kopetz S, Wei SH, Curley SA, Abdalla EK. Systemic Chemotherapy and Two-Stage Hepatectomy for Extensive Bilateral Colorectal Liver Metastases: Perioperative Safety and Survival. Journal Of Gastrointestinal Surgery 2007, 11: 1498-1505. PMID: 17849166, DOI: 10.1007/s11605-007-0272-2.Peer-Reviewed Original ResearchConceptsBilateral colorectal liver metastasesColorectal liver metastasesPreoperative portal vein embolizationTwo-stage hepatectomyGroup IGroup IISystemic chemotherapyLiver metastasesSurvival rateDisease-free survival ratesBackgroundTwo-stage hepatectomyDay postoperative mortalityOne-stage hepatectomyPreoperative systemic chemotherapyGroup II patientsMedian hospital stayOutcomes of patientsPortal vein embolizationTreatment of patientsSecond-stage hepatectomyPostoperative mortalityAggressive surgeryBilateral diseaseHospital stayMajor hepatectomyPortal vein embolization before major hepatectomy and its effects on regeneration, resectability and outcome
Ribero D, Abdalla EK, Madoff DC, Donadon M, Loyer EM, Vauthey J. Portal vein embolization before major hepatectomy and its effects on regeneration, resectability and outcome. British Journal Of Surgery 2007, 94: 1386-1394. PMID: 17583900, DOI: 10.1002/bjs.5836.Peer-Reviewed Original ResearchConceptsPortal vein embolizationHepatic dysfunctionStandardized FLRVein embolizationMortality rateFuture liver remnant volumePostoperative hepatic dysfunctionLiver-related complicationsLiver remnant volumeDegree of hypertrophyHospital stayMajor hepatectomyPostoperative complicationsHepatic resectionLiver resectionRemnant volumePrognostic informationPatientsComplicationsDysfunctionVolumetric evaluationResectionEmbolizationOutcomesCent