2015
Fast Biological Modeling for Voxel-based Heavy Ion Treatment Planning Using the Mechanistic Repair-Misrepair-Fixation Model and Nuclear Fragment Spectra
Kamp F, Cabal G, Mairani A, Parodi K, Wilkens JJ, Carlson DJ. Fast Biological Modeling for Voxel-based Heavy Ion Treatment Planning Using the Mechanistic Repair-Misrepair-Fixation Model and Nuclear Fragment Spectra. International Journal Of Radiation Oncology • Biology • Physics 2015, 93: 557-568. PMID: 26460998, DOI: 10.1016/j.ijrobp.2015.07.2264.Peer-Reviewed Original ResearchConceptsRelative biological effectivenessCarbon ion therapyCarbon ionsIon therapyHeavy ion treatment planningMonte Carlo code FLUKAPrimary carbon ionsCarbon ion energyRadiation therapy beamsRBE valuesCarbon ion treatment plansRelevant RBE valuesRMF predictionsHeavy ionsIon energyDouble-strand break (DSB) yieldsRMF modelEnergy spectrumTherapy beamsSecondary fragmentsMonte Carlo damage simulationNuclear fragmentsBiological optimizationBiological effectivenessRBE predictions
2014
Predicting the Relative Biological Effectiveness of Carbon Ion Radiation Therapy Beams Using the Mechanistic Repair-Misrepair-Fixation (RMF) Model and Nuclear Fragment Spectra
Kamp F, Cabal G, Mairani A, Parodi K, Wilkens J, Carlson D. Predicting the Relative Biological Effectiveness of Carbon Ion Radiation Therapy Beams Using the Mechanistic Repair-Misrepair-Fixation (RMF) Model and Nuclear Fragment Spectra. International Journal Of Radiation Oncology • Biology • Physics 2014, 90: s849. DOI: 10.1016/j.ijrobp.2014.05.2434.Peer-Reviewed Original Research