The Preliminary Analysis of Circulating Human Papillomavirus DNA in a Phase III Trial of Concurrent Chemoradiation (CRT) with Intensity Modulated Proton Therapy (IMPT) vs. IMRT in Oropharyngeal Squamous Cell Carcinoma (OPSCC)
Wang L, Zhang Y, Ausat N, Hernandez M, Rosenthal D, Garden A, Ferrarotto R, Gunn G, Fuller C, Phan J, Morrison W, Lee A, Moreno A, Gross N, Spiotto M, Frank S. The Preliminary Analysis of Circulating Human Papillomavirus DNA in a Phase III Trial of Concurrent Chemoradiation (CRT) with Intensity Modulated Proton Therapy (IMPT) vs. IMRT in Oropharyngeal Squamous Cell Carcinoma (OPSCC). International Journal Of Radiation Oncology • Biology • Physics 2024, 120: s123-s124. DOI: 10.1016/j.ijrobp.2024.07.223.Peer-Reviewed Original ResearchOropharyngeal squamous cell carcinomaIntensity modulated proton therapyDNA scoreConcurrent chemoradiationTreatment failureNode dissectionInduction chemotherapyHuman papillomavirusHPV+ oropharyngeal squamous cell carcinomaHigh risk of treatment failurePhase III randomized trialRisk of treatment failureMulticenter phase III randomized trialPost-induction chemotherapyTreatment de-escalationHuman papillomavirus DNALymph node dissectionPhase III trialsSquamous cell carcinomaPotential of TFAJCC-7RT doseTumor controlTreatment toxicityPost-RTA prospective cohort study on stereotactic radiotherapy in the management of dural recurrence of olfactory neuroblastoma
Goodman C, DeMonte F, Nguyen T, Garden A, Wang C, Wang X, Diao K, Lee A, Reddy J, Moreno A, Spiotto M, Fuller C, Rosenthal D, Ferrarotto R, Raza S, Su S, Warner A, Hanna E, Phan J. A prospective cohort study on stereotactic radiotherapy in the management of dural recurrence of olfactory neuroblastoma. Head & Neck 2024 PMID: 39073252, DOI: 10.1002/hed.27887.Peer-Reviewed Original ResearchStereotactic body radiotherapyOlfactory neuroblastomaOutcomes of stereotactic body radiotherapyTreated with stereotactic body radiotherapyTwo-year local controlHigher local control rateONB patientsPatient-reported quality of lifeLocal control rateProspective cohort studyPatient-reported qualityBrain radionecrosisStereotactic radiotherapyMedian doseTumor controlDural lesionsProspective registryRadiographic progressionControl rateMinimal toxicityCohort studyLocal controlQuality of lifePatientsRecurrence