2022
Effect of Early vs Standard Approach to Tracheostomy on Functional Outcome at 6 Months Among Patients With Severe Stroke Receiving Mechanical Ventilation
Bösel J, Niesen WD, Salih F, Morris NA, Ragland JT, Gough B, Schneider H, Neumann JO, Hwang DY, Kantamneni P, James ML, Freeman WD, Rajajee V, Rao CV, Nair D, Benner L, Meis J, Klose C, Kieser M, Suarez JI, Schönenberger S, Seder DB, Ramadan A, Claassen J, Mayer S, Peled H, Christianson T, May T, Riker R, Asgarpur G, Stetefeld H, Kluge S. Effect of Early vs Standard Approach to Tracheostomy on Functional Outcome at 6 Months Among Patients With Severe Stroke Receiving Mechanical Ventilation. JAMA 2022, 327: 1899-1909. PMID: 35506515, PMCID: PMC9069344, DOI: 10.1001/jama.2022.4798.Peer-Reviewed Original ResearchConceptsEarly tracheostomy groupEarly tracheostomyMechanical ventilationSevere strokeFunctional outcomeStandard tracheostomyTracheostomy groupPrimary outcomeControl groupProlonged invasive mechanical ventilationModified Rankin Scale scoreSevere disabilityInvasive mechanical ventilationSerious adverse eventsRankin Scale scoreAirway protective reflexesRate of survivalInvasive ventilationAdverse eventsHemorrhagic strokeWide confidence intervalsAvailable followProtective reflexesCare centerClinical trials
2020
US Practitioner Attitudes Toward Tracheostomy Timing, Benefits, Risks, and Techniques for Severe Stroke Patients: A National Survey and National Inpatient Sample Analysis
Zhao CW, Hwang DY. US Practitioner Attitudes Toward Tracheostomy Timing, Benefits, Risks, and Techniques for Severe Stroke Patients: A National Survey and National Inpatient Sample Analysis. Neurocritical Care 2020, 34: 669-673. PMID: 33094469, DOI: 10.1007/s12028-020-01127-7.Peer-Reviewed Original Research
2019
Gap Analysis Regarding Prognostication in Neurocritical Care: A Joint Statement from the German Neurocritical Care Society and the Neurocritical Care Society
Wartenberg KE, Hwang DY, Haeusler K, Muehlschlegel S, Sakowitz OW, Madžar D, Hamer HM, Rabinstein AA, Greer DM, Hemphill JC, Meixensberger J, Varelas PN. Gap Analysis Regarding Prognostication in Neurocritical Care: A Joint Statement from the German Neurocritical Care Society and the Neurocritical Care Society. Neurocritical Care 2019, 31: 231-244. PMID: 31368059, PMCID: PMC6757096, DOI: 10.1007/s12028-019-00769-6.Peer-Reviewed Original ResearchConceptsNeurocritical Care SocietyNeurocritical carePrognostic modelNeurocritical care conditionsNumerous prognostic modelsEvidence-based guidelinesCurrent prognostic modelsMost prognostic modelsProcess of prognosticationMedical comorbiditiesMost patientsNeurocritical illnessCare parametersClinical studiesCare conditionsMethodsAs partPrognosticationRoutine partQualitative gap analysisCareFuture studiesSignificant gapJoint statementAbsence of integrationGuidelines
2016
Timing of Percutaneous Endoscopic Gastrostomy for Acute Ischemic Stroke
George BP, Kelly AG, Albert GP, Hwang DY, Holloway RG. Timing of Percutaneous Endoscopic Gastrostomy for Acute Ischemic Stroke. Stroke 2016, 48: 420-427. PMID: 27965430, DOI: 10.1161/strokeaha.116.015119.Peer-Reviewed Original ResearchConceptsAcute ischemic strokeTime-limited trialsNasogastric feedingIschemic strokePEG placementPercutaneous endoscopic gastrostomy (PEG) tube placementEndoscopic gastrostomy tube placementEarly PEG placementSurgical feeding tubeDay of admissionHigh-volume hospitalsPercutaneous endoscopic gastrostomyRetrospective observational studyIschemic stroke admissionsGastrostomy tube placementEffect of patientMultivariable regression analysisAdult age groupsOlder adult age groupsPEG recipientsEarly PEGEndoscopic gastrostomyStroke admissionsMedian timePEG tube