Featured Publications
A novel MGP mutation in a consanguineous family: Review of the clinical and molecular characteristics of Keutel syndrome
Hur DJ, Raymond GV, Kahler SG, Riegert‐Johnson D, Cohen BA, Boyadjiev SA. A novel MGP mutation in a consanguineous family: Review of the clinical and molecular characteristics of Keutel syndrome. American Journal Of Medical Genetics Part A 2005, 135A: 36-40. PMID: 15810001, DOI: 10.1002/ajmg.a.30680.Peer-Reviewed Original ResearchConceptsKeutel syndromeMatrix Gla protein geneOptic nerve atrophyRare autosomal recessive conditionMid-dermal elastolysisFunction mutationsBone morphogenetic protein-2Autosomal recessive conditionConsanguineous Arab familyAbnormal cartilage calcificationNerve atrophyAbnormal calcificationCardinal featuresCalcification inhibitorsWhite matterClinical phenotypeTypical manifestationsRecessive conditionSoft tissueExtracellular matrix proteinsAffected individualsCartilage calcificationProtein 2Consanguineous familyConsensus donor splice siteFrequency of Coronary Artery Disease in Patients Undergoing Peripheral Artery Disease Surgery
Hur DJ, Kizilgul M, Aung WW, Roussillon KC, Keeley EC. Frequency of Coronary Artery Disease in Patients Undergoing Peripheral Artery Disease Surgery. The American Journal Of Cardiology 2012, 110: 736-740. PMID: 22633203, PMCID: PMC3418448, DOI: 10.1016/j.amjcard.2012.04.059.Peer-Reviewed Original ResearchConceptsCoronary artery diseasePeripheral arterial diseaseConcomitant coronary artery diseasePreoperative coronary angiographyCarotid artery diseaseArtery diseaseCoronary angiographyCase seriesCoronary arteryObstructive coronary artery diseaseSevere carotid artery diseaseEpicardial coronary arteriesSimilar risk factorsAngiographic evidenceDisease surgeryPeripheral revascularizationArterial diseaseDiameter narrowingRisk factorsHigh prevalencePatientsSurgeryAngiographyDiseasePrevalenceSerial Native T1 Mapping to Monitor Cardiac Response to Treatment in Light-Chain Amyloidosis
Hur DJ, Dicks DL, Huber S, Mojibian HR, Meadows JL, Seropian SE, Baldassarre LA. Serial Native T1 Mapping to Monitor Cardiac Response to Treatment in Light-Chain Amyloidosis. Circulation Cardiovascular Imaging 2016, 9: e004770. PMID: 27682238, DOI: 10.1161/circimaging.116.004770.Peer-Reviewed Original ResearchMultimodality Imaging Involving Magnetic Resonance Facilitates Giant Symptomatic Myxoma Resection
Hur DJ, Prescher LM, Meadows JL, Pfau SE, Homer RJ, Tellides G, Yun JJ. Multimodality Imaging Involving Magnetic Resonance Facilitates Giant Symptomatic Myxoma Resection. Ann Thorac Surg 2019, 107: e15-e17. PMID: 30558736, DOI: 10.1016/j.athoracsur.2018.05.083.Peer-Reviewed Case Reports and Technical NotesNon-invasive Multimodality Cardiovascular Imaging of the Right Heart and Pulmonary Circulation in Pulmonary Hypertension
Hur DJ, Sugeng L. Non-invasive Multimodality Cardiovascular Imaging of the Right Heart and Pulmonary Circulation in Pulmonary Hypertension. Frontiers In Cardiovascular Medicine 2019, 6: 24. PMID: 30931315, PMCID: PMC6427926, DOI: 10.3389/fcvm.2019.00024.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsMean pulmonary arterial pressureRight heart catheterizationPulmonary hypertensionRight ventricleEvaluation of PHMultimodality cardiovascular imagingPulmonary arterial pressurePulmonary arterial vasculatureNon-invasive imaging methodMillimeters of mercuryHeart catheterizationArterial pressurePrognostic riskRight heartNon-invasive imagingPatient survivalRV structurePulmonary circulationSeverity stratificationEarly initiationArterial vasculatureFunctional assessmentMortality rateRH dysfunctionTreatment managementAn assessment of transesophageal echocardiography studies rated as rarely appropriate tests for infective endocarditis at an academic medical center
Amuchastegui T, Hur DJ, Fillipon N, Eder MD, Bonomo JA, Kim Y, McNamara RL, Malinis M, Sugeng L. An assessment of transesophageal echocardiography studies rated as rarely appropriate tests for infective endocarditis at an academic medical center. Echocardiography 2019, 36: 2070-2077. PMID: 31705577, DOI: 10.1111/echo.14525.Peer-Reviewed Original ResearchConceptsAppropriate use criteriaTransesophageal echocardiographyAcademic medical centerInfective endocarditisMedical CenterTertiary academic medical centerComplex infectious processTransesophageal echocardiography studyRetrospective chart reviewInfectious disease specialistsElectronic medical chartsTEE findingsChart reviewRetrospective cohortDuke criteriaMedical chartsDisease specialistsEchocardiography studyRetrospective studyPhysical examinationEndocardial involvementID specialistsBlood culturesInfectious processTEE useMultimodality Imaging of the Right Heart
Posada-Martinez E, Ortiz-Leon X, Sugeng L, Hur D. Multimodality Imaging of the Right Heart. Clinical Cases In Cardiology 2020, 43-70. DOI: 10.1007/978-3-030-38662-7_3.ChaptersRight ventricleExtent of diseaseInvasive treatment optionQuality of lifePeriprocedural planningPatient selectionRight heartCardiac statusPathophysiologic impactTricuspid valveTreatment optionsPulmonary circulationMultimodality imagingRight sideVentricleTissue characterizationHeartMorbidityPrognosisMortalityDisease#WhyCMR | Social Media | May 1 - 24, 2021
Daryani YP, Hur DJ. #WhyCMR | Social Media | May 1 - 24, 2021. SCMR Newsletter 2021, 6: 5.Commentaries, Editorials and LettersMultimodality Imaging in the Diagnosis of Prosthetic Valve Endocarditis: A Brief Review
Eder MD, Upadhyaya K, Park J, Ringer M, Malinis M, Young BD, Sugeng L, Hur DJ. Multimodality Imaging in the Diagnosis of Prosthetic Valve Endocarditis: A Brief Review. Frontiers In Cardiovascular Medicine 2021, 8: 750573. PMID: 34988125, PMCID: PMC8720921, DOI: 10.3389/fcvm.2021.750573.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsCardiac magnetic resonance imagingInfective endocarditisF-fluorodeoxyglucose positron emission tomographyProsthetic valve endocarditisHigh mortality rateMagnetic resonance imagingPositron emission tomographyValve endocarditisDuke criteriaLeukocyte scintigraphyStandard workupTreatable conditionEchocardiographic dataTomographic angiographyModality strategiesMortality rateResonance imagingEmission tomographyEndocarditisDiagnostic accuracyFurther studiesFormal guidelinesWorkupClinical vignettesDiagnosisAre Cardiology Fellows Receiving Enough Basic Level I Cardiovascular Computed Tomography Education During their General Fellowship Training? Insights from a Needs Assessment Survey at an Academic Medical Center
Hur DJ, Meadows JL, Baldassarre LA, Mojibian HR, Villines TC, Windish DM. Are cardiology fellows receiving enough basic level I cardiovascular computed tomography education during their general fellowship training? Insights from a needs assessment survey at an academic medical center. J Cardiovasc Comput Tomogr 2022, 16: 186-188. PMID: 34600865, DOI: 10.1016/j.jcct.2021.09.005.Peer-Reviewed Original ResearchFrom a priori to evidence and advocacy: The evolving paradigm of CCT competency for structural heart disease
Hur DJ, Wang DD, Choi AD. From a priori to evidence and advocacy: The evolving paradigm of CCT competency for structural heart disease. Journal Of Cardiovascular Computed Tomography 2022, 16: 412-414. PMID: 35618636, DOI: 10.1016/j.jcct.2022.05.001.Commentaries, Editorials and LettersIntegration of three‐dimensional echocardiography into the modern‐day echo laboratory
Hur DJ, Sugeng L. Integration of three-dimensional echocardiography into the modern-day echo laboratory. Echocardiography 2022, 39: 985-1000. PMID: 33305429, DOI: 10.1111/echo.14958.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsContemporary cardiovascular computed tomography (CCT) training: Serial surveys of the international CCT community by the Fellow and Resident Leaders of the Society of Cardiovascular Computed Tomography (SCCT) Committee (FiRST) and SCCT Future Leaders Program (FLP)
Madan N, Hur D, Gannon M, Gupta S, Weir-McCall J, Johns C, Kumar A, Nagpal P, Fentanes E, Lee J, Choi A, Ferencik M, Maroules C, Villines T, Nicol E. Contemporary cardiovascular computed tomography (CCT) training: Serial surveys of the international CCT community by the Fellow and Resident Leaders of the Society of Cardiovascular Computed Tomography (SCCT) Committee (FiRST) and SCCT Future Leaders Program (FLP). Journal Of Cardiovascular Computed Tomography 2023, 17: 226-230. PMID: 37015851, DOI: 10.1016/j.jcct.2023.03.006.Peer-Reviewed Original ResearchHigh- versus low-gradient aortic stenosis: Is our evaluation limited by aorto-mitral angle on cardiovascular CT?
See C, Kim Y, Park J, Wang Y, Reinhardt S, Shkolnik E, Faridi K, Lombo B, Bellumkonda L, McNamara R, Sugeng L, Hur D. High- versus low-gradient aortic stenosis: Is our evaluation limited by aorto-mitral angle on cardiovascular CT? International Journal Of Cardiology 2024, 409: 132174. PMID: 38754590, DOI: 10.1016/j.ijcard.2024.132174.Peer-Reviewed Original ResearchNormal-flow low-gradientAortic valve areaTranscatheter AV replacementParadoxical low-flow low-gradientCardiovascular CTTransthoracic echocardiogramCalcium scoreAS patientsDiagnosis of severe ASLow-gradient aortic stenosisHG-AS patientsLG-AS patientsLow-flow low-gradientAorto-mitral angleAortic valve (AV) stenosisLG-ASPLFLG-ASAV replacementSevere ASConsecutive patientsAortic stenosisValve areaAS phenotypeClinical managementEchocardiogram
2024
Ischemia-Guided Management Using Cardiac SPECT: Reconciling Real-World Evidence in a Post-ISCHEMIA Trial World
Villines T, Hur D. Ischemia-Guided Management Using Cardiac SPECT: Reconciling Real-World Evidence in a Post-ISCHEMIA Trial World. Circulation Cardiovascular Imaging 2024, 17: e017377. PMID: 39247948, PMCID: PMC11408079, DOI: 10.1161/circimaging.124.017377.Peer-Reviewed Original ResearchIntimomedial tears of the aorta heal by smooth muscle cell-mediated fibrosis without atherosclerosis
Hassab A, Hur D, Vallabhajosyula P, Tellides G, Assi R. Intimomedial tears of the aorta heal by smooth muscle cell-mediated fibrosis without atherosclerosis. JCI Insight 2024, 9: e172437. PMID: 38592807, PMCID: PMC11141924, DOI: 10.1172/jci.insight.172437.Peer-Reviewed Original ResearchConceptsDepartment of SurgerySmooth muscle cellsCellular response to injuryResponse to injuryImmunofluorescence confocal microscopyVessel wall repairPrimary lesionAscending aortaConduit functionAneurysmal diseaseDense fibrosisRadiological signsMural hematomaTear progressionMuscle cellsNon-hemorrhagicErythrocyte extravasationWall repairAortaTear completionInduce atherosclerosisHealed lesionsScattered leukocytesMinimal injuryConclusionThese findingsFactors associated with reporting left ventricular ejection fraction with 3D echocardiography in real‐world practice
Faridi K, Zhu Z, Shah N, Crandall I, McNamara R, Flueckiger P, Bachand K, Lombo B, Hur D, Agarwal V, Reinhardt S, Velazquez E, Sugeng L. Factors associated with reporting left ventricular ejection fraction with 3D echocardiography in real‐world practice. Echocardiography 2024, 41: e15774. PMID: 38329886, DOI: 10.1111/echo.15774.Peer-Reviewed Original ResearchConceptsTransthoracic echocardiogramVentricular ejection fractionOutpatient transthoracic echocardiogramsReal-world practiceEjection fractionLeft ventricular ejection fractionAssess left ventricular ejection fractionInpatient transthoracic echocardiogramsMultivariate logistic regressionLVEFHospitalized patientsMedical CenterSonographersClinical settingLogistic regressionUltrasound machineChemotherapyContrast enhancement agentsPortable studiesNegative association
2023
Variation in Reader-Reported Severity of Paradoxical Low-Flow Low-Gradient Aortic Stenosis
Shah N, Sugeng L, Zhang Z, Wang K, McNamara R, Agarwal V, Hur D, Lombo B, Bellumkonda L, Mankbadi M, Basem Dajani A, Forrest J, Krumholz H, Reinhardt S, Velazquez E, Faridi K. Variation in Reader-Reported Severity of Paradoxical Low-Flow Low-Gradient Aortic Stenosis. Journal Of The American Society Of Echocardiography 2023, 37: 466-467. PMID: 37995937, DOI: 10.1016/j.echo.2023.11.014.Peer-Reviewed Original Research
2022
International practice patterns of coronary artery calcium scanning prior to coronary CT angiography
Franklin J, Brown A, Choi A, Hur D, Villines T. International practice patterns of coronary artery calcium scanning prior to coronary CT angiography. Journal Of Cardiovascular Computed Tomography 2022, 17: 62-63. PMID: 36526574, DOI: 10.1016/j.jcct.2022.12.001.Peer-Reviewed Original ResearchTricuspid and mitral remodelling in atrial fibrillation: a three-dimensional echocardiographic study
Ortiz-Leon XA, Posada-Martinez EL, Trejo-Paredes MC, Ivey-Miranda JB, Pereira J, Crandall I, DaSilva P, Bouman E, Brooks A, Gerardi C, Houle H, Hur DJ, Lin BA, McNamara RL, Lombo-Lievano B, Akar JG, Arias-Godinez JA, Sugeng L. Tricuspid and mitral remodelling in atrial fibrillation: a three-dimensional echocardiographic study. European Heart Journal - Cardiovascular Imaging 2022, 23: 944-955. PMID: 35243501, DOI: 10.1093/ehjci/jeac045.Peer-Reviewed Original ResearchConceptsAtrial fibrillationMitral annulusVentricular functionLV functionSinus rhythmThree-dimensional echocardiographic studyImpact of AFNon-valvular atrial fibrillationNormal left ventricular functionTricuspid annulus dilationLV systolic dysfunctionNormal LV functionLeft ventricular functionAbnormal ventricular functionMA dilationTA dilationSystolic dysfunctionFunctional regurgitationAtrial enlargementEchocardiographic studyTransoesophageal echocardiographyAF groupAnnulus dilationAtrioventricular valvePatients