2019
Siponimod Chips Away at Progressive MS
Longbrake EE, Hafler DA. Siponimod Chips Away at Progressive MS. Cell 2019, 179: 1440. PMID: 31951523, PMCID: PMC8023412, DOI: 10.1016/j.cell.2019.11.034.Peer-Reviewed Original ResearchMeSH KeywordsAzetidinesBenzyl CompoundsClinical Trials as TopicHumansMultiple SclerosisUnited StatesUnited States Food and Drug AdministrationConceptsProgressive multiple sclerosisGadolinium-enhancing MRI lesionsInflammatory disease activityImmunomodulatory medicationsDisability progressionDisease activityMRI lesionsProgressive MSNeurologic disabilityPMS patientsMultiple sclerosisSiponimodMedicationsSclerosisPatientsLesionsBedsideProgression
2012
Unraveling the autoimmune translational research process layer by layer
Blumberg RS, Dittel B, Hafler D, von Herrath M, Nestle FO. Unraveling the autoimmune translational research process layer by layer. Nature Medicine 2012, 18: 35-41. PMID: 22227670, PMCID: PMC4592149, DOI: 10.1038/nm.2632.Peer-Reviewed Original ResearchMeSH KeywordsAutoimmune DiseasesDrug ApprovalGenome-Wide Association StudyHumansTranslational Research, BiomedicalUnited StatesUnited States Food and Drug Administration