Human regulatory T cells and their role in autoimmune disease
Baecher‐Allan C, Hafler DA. Human regulatory T cells and their role in autoimmune disease. Immunological Reviews 2006, 212: 203-216. PMID: 16903916, DOI: 10.1111/j.0105-2896.2006.00417.x.Peer-Reviewed Original ResearchConceptsRegulatory T cellsAutoimmune diseasesSelf-reactive cellsT cellsHealthy individualsHuman natural regulatory T cellsSelf-reactive T cellsNatural regulatory T cellsHuman regulatory T cellsPathologic T cellsReduced inhibitory functionSpecific autoimmune diseasesT cell populationsMature T cellsT cell maturationNon-responsive stateRegulatory cellsNatural CD4Peripheral circulationImmune systemPatientsDiseaseInhibitory functionNumber of mechanismsCellsOR.9. Il-10 Plays a Contrasting Role in Suppression By Functionally Distinct, Dr+ and Dr− Human Natural Regulatory T-Cells
Baecher-Allan C, Ashley C, Hafler D. OR.9. Il-10 Plays a Contrasting Role in Suppression By Functionally Distinct, Dr+ and Dr− Human Natural Regulatory T-Cells. Clinical Immunology 2006, 119: s7. DOI: 10.1016/j.clim.2006.04.011.Peer-Reviewed Original Research