1997
Glomerular epithelial cell products stimulate mesangial cell proliferation in culture
Budde K, Neumayer H, Salant D, Cybulsky A, Coleman D, Sterzel R. Glomerular epithelial cell products stimulate mesangial cell proliferation in culture. Kidney International 1997, 52: 733-741. PMID: 9291194, DOI: 10.1038/ki.1997.389.Peer-Reviewed Original ResearchConceptsGlomerular epithelial cellsMC growth factorsMesangial cellsGlomerular diseaseGrowth factorMesangial cell proliferationEpithelial cell productsQuiescent rat mesangial cellsRat mesangial cellsIL-6IL-4IL-5TNF-alphaIL-2Glomerular cell typesIL-1GM-CSFTGF betaSoluble factorsProliferative activityCell productsCompetitive binding assaysEpithelial cellsMitogenic activityCell proliferation
1990
Rat Tracheal Epithelial Cells Produce Granulocyte/Macrophage Colony-stimulating Factor
Smith S, Lee D, Lacy J, Coleman D. Rat Tracheal Epithelial Cells Produce Granulocyte/Macrophage Colony-stimulating Factor. American Journal Of Respiratory Cell And Molecular Biology 1990, 2: 59-68. PMID: 2407273, DOI: 10.1165/ajrcmb/2.1.59.Peer-Reviewed Original ResearchAnimalsAntibodiesCells, CulturedChromatography, High Pressure LiquidColony-Stimulating FactorsCulture MediaDNA ProbesEpithelial CellsEpitheliumGranulocyte-Macrophage Colony-Stimulating FactorGrowth SubstancesLipopolysaccharidesMaleMolecular WeightNucleic Acid HybridizationRatsRats, Inbred F344TracheaTranscription, Genetic
1989
Recombinant granulocyte-macrophage colony-stimulating factor increases adenylate cyclase activity in murine peritoneal macrophages.
Coleman D, Liu J, Bartiss A. Recombinant granulocyte-macrophage colony-stimulating factor increases adenylate cyclase activity in murine peritoneal macrophages. The Journal Of Immunology 1989, 143: 4134-40. PMID: 2687376, DOI: 10.4049/jimmunol.143.12.4134.Peer-Reviewed Original ResearchRat mesangial cells produce granulocyte-macrophage colony-stimulating factor
Budde K, Coleman D, Lacy J, Sterzel R. Rat mesangial cells produce granulocyte-macrophage colony-stimulating factor. American Journal Of Physiology 1989, 257: f1065-f1078. PMID: 2690641, DOI: 10.1152/ajprenal.1989.257.6.f1065.Peer-Reviewed Original ResearchConceptsRat mesangial cellsGranulocyte-macrophage colony-stimulating factorCultured rat mesangial cellsMesangial cellsColony-stimulating factorGM-CSFMC-CMGlomerular mesangial cellsPeritoneal MPsEffector cellsIL-2Inflammatory processGlomerular diseaseInterleukin-2T cellsT lymphocytesInterleukin-4Murine GM-CSFRenal glomeruliSerum-free conditionsSoluble factorsProliferative activitySpecific cDNA probesGM-CSF mRNA transcriptsPresent findingsParathyroid hormone and lipopolysaccharide induce murine osteoblast-like cells to secrete a cytokine indistinguishable from granulocyte-macrophage colony-stimulating factor.
Horowitz M, Coleman D, Flood P, Kupper T, Jilka R. Parathyroid hormone and lipopolysaccharide induce murine osteoblast-like cells to secrete a cytokine indistinguishable from granulocyte-macrophage colony-stimulating factor. Journal Of Clinical Investigation 1989, 83: 149-157. PMID: 2642917, PMCID: PMC303655, DOI: 10.1172/jci113852.Peer-Reviewed Original ResearchConceptsParathyroid hormoneGranulocyte-macrophage colony-stimulating factorColony-stimulating factorOsteoclast activityDose of PTHGM-CSFNumber of osteoclastsSecretion of cytokinesBone active agentsUnknown cytokinesSpecific cytokinesCytokinesCulture resultsPrimary murine osteoblastsActive inductionLipopolysaccharideSecretion of collagenSecretionSerological techniquesNew boneMurine osteoblastsHormone
1988
Keratinocyte Derived T-Cell Growth Factor (KTGF) Is Identical to Granulocyte Macrophage Colony Stimulating Factor (GM-CSF)
Kupper T, Lee F, Coleman D, Chodakewitz J, Flood P, Horowitz M. Keratinocyte Derived T-Cell Growth Factor (KTGF) Is Identical to Granulocyte Macrophage Colony Stimulating Factor (GM-CSF). Journal Of Investigative Dermatology 1988, 91: 185-188. PMID: 3294304, DOI: 10.1111/1523-1747.ep12464470.Peer-Reviewed Original ResearchConceptsS1 nuclease analysisCell linesMurine T cell lineVariety of biochemicalsGrowth factorMurine GM-CSF cDNAGM-CSFNuclease analysisCultured neonatal keratinocytesGM-CSF cDNARecombinant murine GM-CSFMurine GM-CSFKeratinocyte cell lineT-cell activating propertiesT cell growth factorMacrophage-colony stimulating factorT cell linesGranulocyte macrophage-colony stimulating factorImmunochemical criteriaHigh specific activityProliferationSpecific activityColony-Stimulating FactorHT-2 cellsPam 212Granulocyte-macrophage colony-stimulating factor enhances selective effector functions of tissue-derived macrophages.
Coleman D, Chodakewitz J, Bartiss A, Mellors J. Granulocyte-macrophage colony-stimulating factor enhances selective effector functions of tissue-derived macrophages. Blood 1988, 72: 573-8. PMID: 3042043, DOI: 10.1182/blood.v72.2.573.bloodjournal722573.Peer-Reviewed Original ResearchConceptsFc-dependent phagocytosisAnti-Toxoplasma activityGranulocyte-macrophage colony-stimulating factorGM-CSFColony-stimulating factorTissue-derived macrophagesRecombinant GM-CSFClass II major histocompatibility antigensMacrophage oxidative metabolismMajor histocompatibility antigensSite of exposureGM-CSF antibodyMurine recombinant GM-CSFThioglycollate-elicited cellsPhorbol myristate acetateNeutrophil functionHistocompatibility antigensEffector functionsVariety of cellsFunctional capacityMacrophage functionThioglycollate-elicited macrophagesResident macrophagesPeritoneal macrophagesStimulatory effect