1997
Glomerular epithelial cell products stimulate mesangial cell proliferation in culture
Budde K, Neumayer H, Salant D, Cybulsky A, Coleman D, Sterzel R. Glomerular epithelial cell products stimulate mesangial cell proliferation in culture. Kidney International 1997, 52: 733-741. PMID: 9291194, DOI: 10.1038/ki.1997.389.Peer-Reviewed Original ResearchConceptsGlomerular epithelial cellsMC growth factorsMesangial cellsGlomerular diseaseGrowth factorMesangial cell proliferationEpithelial cell productsQuiescent rat mesangial cellsRat mesangial cellsIL-6IL-4IL-5TNF-alphaIL-2Glomerular cell typesIL-1GM-CSFTGF betaSoluble factorsProliferative activityCell productsCompetitive binding assaysEpithelial cellsMitogenic activityCell proliferation
1989
Rat mesangial cells produce granulocyte-macrophage colony-stimulating factor
Budde K, Coleman D, Lacy J, Sterzel R. Rat mesangial cells produce granulocyte-macrophage colony-stimulating factor. American Journal Of Physiology 1989, 257: f1065-f1078. PMID: 2690641, DOI: 10.1152/ajprenal.1989.257.6.f1065.Peer-Reviewed Original ResearchConceptsRat mesangial cellsGranulocyte-macrophage colony-stimulating factorCultured rat mesangial cellsMesangial cellsColony-stimulating factorGM-CSFMC-CMGlomerular mesangial cellsPeritoneal MPsEffector cellsIL-2Inflammatory processGlomerular diseaseInterleukin-2T cellsT lymphocytesInterleukin-4Murine GM-CSFRenal glomeruliSerum-free conditionsSoluble factorsProliferative activitySpecific cDNA probesGM-CSF mRNA transcriptsPresent findings
1987
Stimulation of macrophage H2O2 release by resident thymocytes: Effect of a soluble factor distinct from interferon-γ
Mellors J, Bartiss A, Coleman D. Stimulation of macrophage H2O2 release by resident thymocytes: Effect of a soluble factor distinct from interferon-γ. Cellular Immunology 1987, 110: 391-399. PMID: 3121188, DOI: 10.1016/0008-8749(87)90131-6.Peer-Reviewed Original ResearchConceptsT cellsResident thymocytesAntigen-specific immune responsesSoluble factorsMacrophage microbicidal mechanismsRespiratory burst capacityLow molecular weight soluble factorMacrophage oxidative metabolismNonactivated T cellsMacrophage H2O2 releaseActivated T cellsMacrophage effector functionsEnzyme-linked immunosorbentReceptor-mediated phagocytosisImmune responseIFN-gammaEffector functionsToxoplasma gondiiControl macrophagesRespiratory burstMicrobicidal mechanismsPeritoneal macrophagesInterferon activityMacrophagesBurst capacity