Parathyroid hormone and lipopolysaccharide induce murine osteoblast-like cells to secrete a cytokine indistinguishable from granulocyte-macrophage colony-stimulating factor.
Horowitz M, Coleman D, Flood P, Kupper T, Jilka R. Parathyroid hormone and lipopolysaccharide induce murine osteoblast-like cells to secrete a cytokine indistinguishable from granulocyte-macrophage colony-stimulating factor. Journal Of Clinical Investigation 1989, 83: 149-157. PMID: 2642917, PMCID: PMC303655, DOI: 10.1172/jci113852.Peer-Reviewed Original ResearchConceptsParathyroid hormoneGranulocyte-macrophage colony-stimulating factorColony-stimulating factorOsteoclast activityDose of PTHGM-CSFNumber of osteoclastsSecretion of cytokinesBone active agentsUnknown cytokinesSpecific cytokinesCytokinesCulture resultsPrimary murine osteoblastsActive inductionLipopolysaccharideSecretion of collagenSecretionSerological techniquesNew boneMurine osteoblastsHormone