1992
Interleukin-6: An autocrine regulator of mesangial cell growth
Coleman D, Ruef C. Interleukin-6: An autocrine regulator of mesangial cell growth. Kidney International 1992, 41: 604-606. PMID: 1573836, DOI: 10.1038/ki.1992.91.Peer-Reviewed Original ResearchConceptsInterleukin-6Transgenic miceVivo studiesTransgenic mouse modelMesangial cell growthIL-6 geneGranulocyte-macrophage colonyIgG1 plasmacytosisCytokine productionImmune cellsMesangioproliferative glomerulonephritisInterleukin-1Autocrine regulatorMouse modelGlomerular cellsCell culture modelProliferative effectTarget cellsTissue distributionImmunoglobulin heavy chain enhancerChain enhancerTissue cellsCulture modelMiceNontransformed cell types
1988
Granulocyte-Macrophage Colony-Stimulating Factor Enhances Selective Effector Functions of Tissue-Derived Macrophages
Coleman D, Chodakewitz J, Bartiss A, Mellors J. Granulocyte-Macrophage Colony-Stimulating Factor Enhances Selective Effector Functions of Tissue-Derived Macrophages. Blood 1988, 72: 573-578. DOI: 10.1182/blood.v72.2.573.573.Peer-Reviewed Original ResearchFc-dependent phagocytosisAnti-Toxoplasma activityGM-CSFTissue-derived macrophagesRecombinant GM-CSFClass II major histocompatibility antigensGranulocyte-macrophage colony-stimulating factorMacrophage oxidative metabolismMajor histocompatibility antigensSite of exposureGM-CSF antibodyColony-stimulating factorMurine recombinant GM-CSFThioglycollate-elicited cellsGranulocyte-macrophage colonyPhorbol myristate acetateNeutrophil functionHistocompatibility antigensEffector functionsVariety of cellsFunctional capacityMacrophage functionThioglycollate-elicited macrophagesResident macrophagesPeritoneal macrophages